Regulon of MetJ in Vibrio vulnificus CMCP6

Properties
Regulator type:	Transcription factor
TF locus tag:	VV1_1362
Regulator family:	MetJ
Regulation mode:	repressor
Biological process:	Methionine metabolism; Methionine biosynthesis
Effector:	S-adenosylmethionine
Regulog:	MetJ - Vibrionales
Statistics of regulated genes:
- Genes	17
- Operons	12
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 218 sites [see more]

Member of regulog collections

By taxonomy - Vibrionales
By trascription factor - MetJ
By TF family - MetJ
By effector - S-adenosylmethionine
By pathway - Methionine metabolism
By pathway - Methionine biosynthesis

Regulated operons
	Locus Tag	Name	Function
Position: -51 Score: 5.6 Sequence: ATAGGTTT-(0)-AGATGTAT Position: -43 Score: 8 Sequence: AGATGTAT-(0)-AGACGTCT Locus tag: VV1_2772 Name: metA Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
	VV1_2772	metA	Homoserine O-succinyltransferase (EC 2.3.1.46)
Position: -222 Score: 6.8 Sequence: GGAAGTAT-(0)-AGATGGCT Locus tag: VV1_1173 Name: btuB Funciton: TonB-dependent outer membrane transporter for vitamin B12
	VV1_1173	btuB	TonB-dependent outer membrane transporter for vitamin B12
Position: -135 Score: 8.1 Sequence: AGACATAT-(0)-AGACGTCT Position: -127 Score: 7.4 Sequence: AGACGTCT-(0)-AGAAGTGT Position: -119 Score: 6.6 Sequence: AGAAGTGT-(0)-TGACGTCT Locus tag: VV1_1364 Name: metB Funciton: Cystathionine gamma-synthase (EC 2.5.1.48) Locus tag: VV1_1365 Name: metL Funciton: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
	VV1_1364	metB	Cystathionine gamma-synthase (EC 2.5.1.48)
	VV1_1365	metL	Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
Position: -122 Score: 7 Sequence: GAACGTTT-(0)-AGACGTCT Position: -114 Score: 7.1 Sequence: AGACGTCT-(0)-AGACGTAA Position: -106 Score: 6.1 Sequence: AGACGTAA-(0)-AAATATCT Locus tag: VV1_0292 Name: metN Funciton: Methionine ABC transporter ATP-binding protein Locus tag: VV1_0293 Name: metI Funciton: Methionine ABC transporter permease protein Locus tag: VV1_0294 Name: metQ Funciton: Methionine ABC transporter substrate-binding protein
	VV1_0292	metN	Methionine ABC transporter ATP-binding protein
	VV1_0293	metI	Methionine ABC transporter permease protein
	VV1_0294	metQ	Methionine ABC transporter substrate-binding protein
Position: -67 Score: 7.3 Sequence: AGACGTCT-(0)-AGACTCCT Locus tag: VV1_1423 Name: metH Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
	VV1_1423	metH	5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
Position: -108 Score: 6 Sequence: AGACGTCA-(0)-ACACTTCT Position: -100 Score: 6.9 Sequence: ACACTTCT-(0)-AGACGTCT Position: -92 Score: 7.7 Sequence: AGACGTCT-(0)-ATATGTCT Locus tag: VV1_1362 Name: metJ Funciton: S-adenosylmethionine-responsive transcriptional repressor MetJ
	VV1_1362	metJ	S-adenosylmethionine-responsive transcriptional repressor MetJ
Position: -181 Score: 5.6 Sequence: AGACATCC-(0)-AGACAGAT Locus tag: VV21534 Name: mtsA Funciton: Substrate-specific component MtsA of methionine-regulated ECF transporter Locus tag: VV21533 Name: mtsB Funciton: Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter Locus tag: VV21532 Name: mtsC Funciton: Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter
	VV21534	mtsA	Substrate-specific component MtsA of methionine-regulated ECF transporter
	VV21533	mtsB	Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter
	VV21532	mtsC	Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter
Position: -43 Score: 5.1 Sequence: GGTCATAT-(0)-GGATGTGT Locus tag: VV1_2808 Name: csd Funciton: Cysteine desulfurase (EC 2.8.1.7)
	VV1_2808	csd	Cysteine desulfurase (EC 2.8.1.7)
Position: -74 Score: 7.3 Sequence: GGACATAT-(0)-AGACGTCT Position: -66 Score: 7.3 Sequence: AGACGTCT-(0)-AAACGTCG Locus tag: VV1_1366 Name: metF Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
	VV1_1366	metF	5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Position: -98 Score: 7.2 Sequence: AGACGTCT-(0)-AGATGTAG Locus tag: VV1_1536 Name: metK Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
	VV1_1536	metK	S-adenosylmethionine synthetase (EC 2.5.1.6)
Position: -197 Score: 7.1 Sequence: AGATGTCT-(0)-GGATGGCT Position: -82 Score: 8 Sequence: AGACGTCT-(0)-AGATGTTT Locus tag: VV1_2218 Name: metR Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
	VV1_2218	metR	Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
Position: -255 Score: 7.5 Sequence: AAACATCT-(0)-AGACGTCT Position: -140 Score: 6.3 Sequence: AGCCATCC-(0)-AGACATCT Locus tag: VV1_2219 Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
	VV1_2219	metE	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of MetJ in Vibrio vulnificus CMCP6

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --