Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of MtaR in Streptococcus pneumoniae TIGR4

Properties
Regulator type: Transcription factor
TF locus tag: SP_0676
Regulator family: LysR
Regulation mode: repressor
Biological process: Methionine metabolism
Effector: Homocysteine
Regulog: MtaR - Streptococcaceae
Statistics of regulated genes:
- Genes 15
- Operons 7
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 72 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -93
Score: 6.2
Sequence: TATAGTTTGAAACTATA
Locus tag: SP_1525
Name: metB
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: SP_1524
Name: csd
Funciton: Cysteine desulfurase (EC 2.8.1.7)
SP_1525
metB
Cystathionine gamma-synthase (EC 2.5.1.48)
SP_1524
csd
Cysteine desulfurase (EC 2.8.1.7)
Position: -99
Score: 6.5
Sequence: TATAGTTTTAAACTATA
Locus tag: SP_0149
Name: metQ
Funciton: Methionine ABC transporter, substrate-binding protein
Locus tag: SP_0150
Name: hmrB
Funciton: N-acyl-L-amino acid amidohydrolase (EC 3.5.1.14)
Locus tag: SP_0151
Name: metN
Funciton: Methionine ABC transporter, ATP-binding protein
Locus tag: SP_0152
Name: metP
Funciton: Methionine ABC transporter, permease protein
SP_0149
metQ
Methionine ABC transporter, substrate-binding protein
SP_0150
hmrB
N-acyl-L-amino acid amidohydrolase (EC 3.5.1.14)
SP_0151
metN
Methionine ABC transporter, ATP-binding protein
SP_0152
metP
Methionine ABC transporter, permease protein
Position: -109
Score: 5.4
Sequence: TATAATTGAAAACTATA
Locus tag: SP_1576
Name: metA
Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
SP_1576
metA
Homoserine O-succinyltransferase (EC 2.3.1.46)
Position: -64
Score: 4.6
Sequence: TATAAGGTAAAACTATA
Locus tag: SP_0481
Name: COG1912
Funciton: Conserved hypothetical protein
Locus tag: SP_0482
Name: mtsA
Funciton: Substrate-specific component MtsA of methionine-regulated ECF transporter
Locus tag: SP_0483
Name: mtsB
Funciton: Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter
Locus tag: SP_0484
Name: mtsC
Funciton: Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter
SP_0481
COG1912
Conserved hypothetical protein
SP_0482
mtsA
Substrate-specific component MtsA of methionine-regulated ECF transporter
SP_0483
mtsB
Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter
SP_0484
mtsC
Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter
Position: -156
Score: 6.4
Sequence: TATAGTTTCAAACTATA
Locus tag: SP_1229
Name: fhs
Funciton: Formate--tetrahydrofolate ligase (EC 6.3.4.3)
SP_1229
fhs
Formate--tetrahydrofolate ligase (EC 6.3.4.3)
Position: -98
Score: 6.3
Sequence: TATAGTTTAAAGCTATA
Locus tag: SP_0825
Name: folD
Funciton: Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
SP_0825
folD
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
Position: -99
Score: 6.4
Sequence: TATAGTTTCAAACTATA
Locus tag: SP_0585
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Locus tag: SP_0586
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
SP_0585
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
SP_0586
metF
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
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