Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of MtaR in Streptococcus mutans UA159

Properties
Regulator type: Transcription factor
TF locus tag: SMU.1225
Regulator family: LysR
Regulation mode: repressor
Biological process: Methionine metabolism
Effector: Homocysteine
Regulog: MtaR - Streptococcaceae
Statistics of regulated genes:
- Genes 15
- Operons 7
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 72 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -100
Score: 6.1
Sequence: TATAGTTTTTAGCTATA
Locus tag: SMU.1941
Name: metQ
Funciton: Methionine ABC transporter, substrate-binding protein
Locus tag: SMU.1940c
Name: hmrB
Funciton: N-acyl-L-amino acid amidohydrolase (EC 3.5.1.14)
Locus tag: SMU.1939c
Name: metN
Funciton: Methionine ABC transporter, ATP-binding protein
Locus tag: SMU.1938c
Name: metP
Funciton: Methionine ABC transporter, permease protein
metQ
Methionine ABC transporter, substrate-binding protein
hmrB
N-acyl-L-amino acid amidohydrolase (EC 3.5.1.14)
metN
Methionine ABC transporter, ATP-binding protein
metP
Methionine ABC transporter, permease protein

Position: -110
Score: 5.4
Sequence: TATAGGTAATAACTATA
Locus tag: SMU.1936c
Name: COG1912
Funciton: Conserved hypothetical protein
Locus tag: SMU.1935c
Name: mtsA
Funciton: Substrate-specific component MtsA of methionine-regulated ECF transporter
Locus tag: SMU.1934c
Name: mtsB
Funciton: Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter
Locus tag: SMU.1933c
Name: mtsC
Funciton: Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter
COG1912
Conserved hypothetical protein
mtsA
Substrate-specific component MtsA of methionine-regulated ECF transporter
mtsB
Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter
mtsC
Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter

Position: -102
Score: 5.3
Sequence: TATAGTTGGAACCTATA
Position: -68
Score: 5.2
Sequence: TATATTTGATAACTATA
Locus tag: SMU.1466
Name: metA
Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
metA
Homoserine O-succinyltransferase (EC 2.3.1.46)

Position: -93
Score: 4.6
Sequence: TATAATATTTAAATATA
Locus tag: SMU.572
Name: folD
Funciton: Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
folD
Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)

Position: -66
Score: 6.3
Sequence: TATAGTTTATAACTATA
Locus tag: SMU.1173
Name: metY
Funciton: O-acetylhomoserine sulfhydrylase (EC 2.5.1.49)
Locus tag: SMU.1172c
Name: COG1878
Funciton: Metal-dependent hydrolase (EC 3.-.-.-)
metY
O-acetylhomoserine sulfhydrylase (EC 2.5.1.49)
COG1878
Metal-dependent hydrolase (EC 3.-.-.-)

Position: -100
Score: 6.5
Sequence: TATAGTTTAAAACTATA
Locus tag: SMU.1487
Name: metE2
Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
metE2
Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)

Position: -186
Score: 5.6
Sequence: TATAGATGAAAACTATA
Position: -155
Score: 6.1
Sequence: TATAGCTTAAAACTATA
Locus tag: SMU.873
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Locus tag: SMU.874
Name: metH
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) / Homolog of homocysteine-binding domain
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
metH
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) / Homolog of homocysteine-binding domain
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD