Regulon of MtaR in Streptococcus mitis B6

Properties
Regulator type:	Transcription factor
TF locus tag:	smi_1461
Regulator family:	LysR
Regulation mode:	repressor
Biological process:	Methionine metabolism
Effector:	Homocysteine
Regulog:	MtaR - Streptococcaceae
Statistics of regulated genes:
- Genes	14
- Operons	6
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 72 sites [see more]

Member of regulog collections

By taxonomy - Streptococcaceae
By TF family - LysR
By effector - Homocysteine
By pathway - Methionine metabolism

Regulated operons
	Locus Tag	Name	Function
Position: -99 Score: 6.2 Sequence: TATAGCTTTAAACTATA Locus tag: smi_1944 Name: metQ Funciton: Methionine ABC transporter, substrate-binding protein Locus tag: smi_1943 Name: hmrB Funciton: N-acyl-L-amino acid amidohydrolase (EC 3.5.1.14) Locus tag: smi_1942 Name: metN Funciton: Methionine ABC transporter, ATP-binding protein Locus tag: smi_1941 Name: metP Funciton: Methionine ABC transporter, permease protein
	smi_1944	metQ	Methionine ABC transporter, substrate-binding protein
	smi_1943	hmrB	N-acyl-L-amino acid amidohydrolase (EC 3.5.1.14)
	smi_1942	metN	Methionine ABC transporter, ATP-binding protein
	smi_1941	metP	Methionine ABC transporter, permease protein
Position: -93 Score: 6.2 Sequence: TATAGTTTGAAACTATA Locus tag: smi_1508 Name: metB Funciton: Cystathionine gamma-synthase (EC 2.5.1.48) Locus tag: smi_1507 Name: csd Funciton: Cysteine desulfurase (EC 2.8.1.7)
	smi_1508	metB	Cystathionine gamma-synthase (EC 2.5.1.48)
	smi_1507	csd	Cysteine desulfurase (EC 2.8.1.7)
Position: -91 Score: 4.6 Sequence: TATAAGGTAAAACTATA Locus tag: smi_1812 Name: COG1912 Funciton: Conserved hypothetical protein Locus tag: smi_1811 Name: mtsA Funciton: Substrate-specific component MtsA of methionine-regulated ECF transporter Locus tag: smi_1810 Name: mtsB Funciton: Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter Locus tag: smi_1809 Name: mtsC Funciton: Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter
	smi_1812	COG1912	Conserved hypothetical protein
	smi_1811	mtsA	Substrate-specific component MtsA of methionine-regulated ECF transporter
	smi_1810	mtsB	Duplicated ATPase component MtsB of energizing module of methionine-regulated ECF transporter
	smi_1809	mtsC	Transmembrane component MtsC of energizing module of methionine-regulated ECF transporter
Position: -35 Score: 6.2 Sequence: TATAGTTTGAAACTATA Locus tag: smi_0869 Name: folD Funciton: Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
	smi_0869	folD	Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
Position: -157 Score: 6.4 Sequence: TATAGTTTCAAACTATA Locus tag: smi_1192 Name: fhs Funciton: Formate--tetrahydrofolate ligase (EC 6.3.4.3)
	smi_1192	fhs	Formate--tetrahydrofolate ligase (EC 6.3.4.3)
Position: -99 Score: 6.4 Sequence: TATAGTTTCAAACTATA Locus tag: smi_1600 Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) Locus tag: smi_1599 Name: metF Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
	smi_1600	metE	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
	smi_1599	metF	5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of MtaR in Streptococcus mitis B6

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --