Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of LiuR in Aeromonas salmonicida subsp. salmonicida A449

Properties
Regulator type: Transcription factor
TF locus tag: ASA_2160, ASA_1907
Regulator family: MerR
Regulation mode: repressor
Biological process: Branched-chain amino acid degradation
Effector:
Regulog: LiuR - Psychromonadaceae/Aeromonadales
Statistics of regulated genes:
- Genes 22
- Operons 7
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 20 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -89
Score: 5
Sequence: CCTTACCCAAACGTCAAC
Locus tag: ASA_2159
Name: ivdA
Funciton: 3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16)
ivdA
3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16)

Position: -60
Score: 5.8
Sequence: ATTGACGTTAACGTAAAC
Position: -54
Score: 4.6
Sequence: GTTAACGTAAACGTGATA
Locus tag: ASA_2041
Name: prpB
Funciton: Methylisocitrate lyase (EC 4.1.3.30)
Locus tag: ASA_2040
Name: prpC
Funciton: 2-methylcitrate synthase (EC 2.3.3.5)
Locus tag: ASA_2039
Name: prpD
Funciton: 2-methylcitrate dehydratase (EC 4.2.1.79)
prpB
Methylisocitrate lyase (EC 4.1.3.30)
prpC
2-methylcitrate synthase (EC 2.3.3.5)
prpD
2-methylcitrate dehydratase (EC 4.2.1.79)

Position: -158
Score: 6.2
Sequence: GTTTACGTTAGCGTAAAC
Position: -152
Score: 4.8
Sequence: GTTAGCGTAAACGTAAAT
Locus tag: ASA_1913
Name: ivdB
Funciton: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
Locus tag: ASA_1914
Name: ivdC
Funciton: Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
Locus tag: ASA_1915
Name: ivdD
Funciton: 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
Locus tag: ASA_1916
Name: ivdE
Funciton: Enoyl-CoA hydratase/isomerase family protein
Locus tag: ASA_1917
Name: ivdF
Funciton: 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
Locus tag: ASA_1918
Name: ivdG
Funciton: 3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)
ivdB
Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
ivdC
Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
ivdD
3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
ivdE
Enoyl-CoA hydratase/isomerase family protein
ivdF
3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
ivdG
3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)

Position: -86
Score: 6.3
Sequence: GTTTACGTAAACGTAAAG
Locus tag: ASA_1856
Name: etfB
Funciton: Electron transfer flavoprotein, beta subunit
Locus tag: ASA_1857
Name: etfA
Funciton: Electron transfer flavoprotein, alpha subunit
etfB
Electron transfer flavoprotein, beta subunit
etfA
Electron transfer flavoprotein, alpha subunit

Position: -58
Score: 6.3
Sequence: CTTTACGTTTACGTAAAC
Locus tag: ASA_1855
Name: etfD
Funciton: Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)
etfD
Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)

Position: -118
Score: 4.8
Sequence: ATTTACGTTTACGCTAAC
Position: -112
Score: 6.2
Sequence: GTTTACGCTAACGTAAAC
Locus tag: ASA_1912
Name: liuA
Funciton: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
Locus tag: ASA_1911
Name: liuB
Funciton: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
Locus tag: ASA_1910
Name: liuC
Funciton: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
Locus tag: ASA_1909
Name: liuD
Funciton: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
Locus tag: ASA_1908
Name: liuE
Funciton: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
Locus tag: ASA_1907
Name: liuR1
Funciton: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
Locus tag: ASA_1906
Name: null
Funciton: Periplasmic binding protein
Locus tag: ASA_1905
Name: null
Funciton: hypothetical protein
liuA
Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
liuB
Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
liuC
Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
liuD
Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
liuE
Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
liuR1
Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
Periplasmic binding protein
hypothetical protein

Position: -61
Score: 5
Sequence: GTTGACGTTTGGGTAAGG
Locus tag: ASA_2160
Name: liuR2
Funciton: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
liuR2
Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
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