Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Fur in Vibrio harveyi ATCC BAA-1116

Properties
Regulator type: Transcription factor
TF locus tag: VIBHAR_01339
Regulator family: FUR
Regulation mode: repressor (activator)
Biological process: Iron homeostasis
Effector: Iron ion, (Fe2+)
Regulog: Fur - Vibrionales
Statistics of regulated genes:
- Genes 94
- Operons 45
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 447 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -134
Score: 5.2
Sequence: AAATGATAATTATTGATATTT
Locus tag: VIBHAR_01762
Name: viuA
Funciton: Ferric aerobactin receptor, TonB-dependent
viuA
Ferric aerobactin receptor, TonB-dependent

Position: -154
Score: 5.3
Sequence: TATTGCTAATCATTATCAACT
Position: -109
Score: 5.6
Sequence: AAATAAGATCAATTATCAATT
Locus tag: VIBHAR_05245
Name: hutW
Funciton: Radical SAM family protein HutW, similar to coproporphyrinogen III oxidase, oxygen-independent, associated with heme uptake
Locus tag: VIBHAR_05246
Name: huvX
Funciton: Putative heme iron utilization protein
Locus tag: VIBHAR_05247
Name: hutZ
Funciton: Pyridoxamine 5'-phosphate oxidase-related putative heme iron utilization protein # hutZ
hutW
Radical SAM family protein HutW, similar to coproporphyrinogen III oxidase, oxygen-independent, associated with heme uptake
huvX
Putative heme iron utilization protein
hutZ
Pyridoxamine 5'-phosphate oxidase-related putative heme iron utilization protein # hutZ

Position: -69
Score: 4.6
Sequence: TATTGTAAATGATTATTGTTT
Position: -63
Score: 4.4
Sequence: AAATGATTATTGTTTGCAAAA
Locus tag: VIBHAR_02101
Name: vibF
Funciton: nonribosomal peptide synthetase VibF
vibF
nonribosomal peptide synthetase VibF

Position: -311
Score: 6
Sequence: AATTAATAATAATTCTCATTT
Position: -305
Score: 4.4
Sequence: TAATAATTCTCATTTTCAATA
Locus tag: VIBHAR_06129
Name: VCA0743
Funciton: uroporphyrinogen decarboxylase
VCA0743
uroporphyrinogen decarboxylase

Position: -57
Score: 5.5
Sequence: AGTTGATAATGATTTTCATTA
Position: -51
Score: 4.8
Sequence: TAATGATTTTCATTAACATTA
Locus tag: VIBHAR_00151
Name: sodA
Funciton: Manganese superoxide dismutase (EC 1.15.1.1)
sodA
Manganese superoxide dismutase (EC 1.15.1.1)

Position: -57
Score: 5.5
Sequence: TATTGAGATTTATTATCATCT
Locus tag: VIBHAR_00267
Name: COG3315
Funciton: O-Methyltransferase involved in polyketide biosynthesis
COG3315
O-Methyltransferase involved in polyketide biosynthesis

Position: -60
Score: 6
Sequence: TAATGATAATAATTCTCAATA
Locus tag: VIBHAR_03638
Name: VC0426
Funciton: Predicted membrane protein
VC0426
Predicted membrane protein

Position: -65
Score: 5.4
Sequence: AACTGAGAATCATTATTAATA
Locus tag: VIBHAR_00368
Name: COG2132
Funciton: Multicopper oxidase
COG2132
Multicopper oxidase

Position: -81
Score: 5.2
Sequence: GAATGATAGTAATTACCATTT
Locus tag: VIBHAR_05789
Name: hutA
Funciton: TonB-dependent heme and hemoglobin receptor HutA ; TonB-dependent hemin , ferrichrome receptor
hutA
TonB-dependent heme and hemoglobin receptor HutA ; TonB-dependent hemin , ferrichrome receptor

Position: -73
Score: 4.8
Sequence: AAATGAAAACAAGTCGCACTT
Position: -50
Score: 5.8
Sequence: AATTGATAATTAATTTCATTT
Locus tag: VIBHAR_05095
Name: VV20793
Funciton: Conserved hypothetical protein
Locus tag: VIBHAR_05094
Name: VV20794
Funciton: ABC transporter, ATP-binding protein
VV20793
Conserved hypothetical protein
VV20794
ABC transporter, ATP-binding protein

Position: -2
Score: 4.9
Sequence: AAATGAGAATTAGTTTCGTTA
Locus tag: VIBHAR_06301
Name: null
Funciton: hypothetical protein
Locus tag: VIBHAR_06300
Name: VV21338
Funciton: HTH-type transcription regulator, AraC-family
hypothetical protein
VV21338
HTH-type transcription regulator, AraC-family

Position: -111
Score: 5.1
Sequence: AAATGATAATTAATCCTATCA
Locus tag: VIBHAR_02109
Name: VV20830
Funciton: Non-ribosomal peptide synthetase modules, siderophore biosynthesis # vulnibactin-specific
VV20830
Non-ribosomal peptide synthetase modules, siderophore biosynthesis # vulnibactin-specific

Position: -197
Score: 4.6
Sequence: CAATGTAAATGGTTCTCAATT
Locus tag: VIBHAR_06272
Name: VV20568
Funciton: Cytochrome c oxidase polypeptide II (EC 1.9.3.1)
Locus tag: VIBHAR_06271
Name: VV20567
Funciton: Cytochrome c oxidase polypeptide I (EC 1.9.3.1)
Locus tag: VIBHAR_06270
Name: VV20566
Funciton: Cytochrome oxidase biogenesis protein Cox11-CtaG, copper delivery to Cox1
Locus tag: VIBHAR_06269
Name: VV20565
Funciton: Cytochrome c oxidase polypeptide III (EC 1.9.3.1)
VV20568
Cytochrome c oxidase polypeptide II (EC 1.9.3.1)
VV20567
Cytochrome c oxidase polypeptide I (EC 1.9.3.1)
VV20566
Cytochrome oxidase biogenesis protein Cox11-CtaG, copper delivery to Cox1
VV20565
Cytochrome c oxidase polypeptide III (EC 1.9.3.1)

Position: -58
Score: 5.3
Sequence: ACTTGATAATAATTATCGTTT
Locus tag: VIBHAR_02989
Name: PF10952
Funciton: Protein of unknown function (DUF2753)
PF10952
Protein of unknown function (DUF2753)

Position: -41
Score: 5.7
Sequence: AATTGATAATGATTTTCAATA
Position: -35
Score: 5
Sequence: TAATGATTTTCAATATCAATT
Locus tag: VIBHAR_03036
Name: null
Funciton: hypothetical protein
Locus tag: VIBHAR_03037
Name: PF00106
Funciton: Short chain dehydrogenase
hypothetical protein
PF00106
Short chain dehydrogenase

Position: -119
Score: 4.6
Sequence: TAATGCGAGTGATAATTATTA
Position: -113
Score: 5
Sequence: GAGTGATAATTATTATCAAAA
Position: -50
Score: 5.3
Sequence: AAATGAGAAGGGATCTCATTT
Locus tag: VIBHAR_01398
Name: VC0773
Funciton: Isochorismate synthase (EC 5.4.4.2) of siderophore biosynthesis # Vibriobactin-specific
Locus tag: VIBHAR_01399
Name: VC0772
Funciton: 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) # Vibriobactin-specific, VibE
VC0773
Isochorismate synthase (EC 5.4.4.2) of siderophore biosynthesis # Vibriobactin-specific
VC0772
2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) # Vibriobactin-specific, VibE

Position: -46
Score: 4.5
Sequence: TGATGTAAAGTATTCTCATTA
Locus tag: VIBHAR_02532
Name: COG2910
Funciton: Putative NADH-flavin reductase
COG2910
Putative NADH-flavin reductase

Position: -42
Score: 5.7
Sequence: TAATAATAATATTTATCATTA
Locus tag: VIBHAR_01363
Name: feoA
Funciton: Ferrous iron transport protein A
Locus tag: VIBHAR_01364
Name: feoB
Funciton: Ferrous iron transport protein B
Locus tag: VIBHAR_01365
Name: feoC
Funciton: Ferrous iron transport protein C
feoA
Ferrous iron transport protein A
feoB
Ferrous iron transport protein B
feoC
Ferrous iron transport protein C

Position: -48
Score: 5.6
Sequence: AAATGAGATTTATTACTATTT
Locus tag: VIBHAR_06299
Name: fhuA
Funciton: TonB-dependent outer membrane receptor for iron siderophores
Locus tag: VIBHAR_06298
Name: fhuD
Funciton: Ferrichrome-binding periplasmic protein precursor (TC 3.A.1.14.3)
Locus tag: VIBHAR_06297
Name: fhuB
Funciton: Ferrichrome transport system permease protein FhuB
fhuA
TonB-dependent outer membrane receptor for iron siderophores
fhuD
Ferrichrome-binding periplasmic protein precursor (TC 3.A.1.14.3)
fhuB
Ferrichrome transport system permease protein FhuB

Position: -95
Score: 5
Sequence: TATTGATATTACTTCTCAGTT
Locus tag: VIBHAR_06007
Name: fepB
Funciton: ABC-type Fe3+-siderophores transport systems, periplasmic component
Locus tag: VIBHAR_06008
Name: fepD
Funciton: ABC-type Fe3+-siderophore transport system, permease component
Locus tag: VIBHAR_06009
Name: fepD
Funciton: ABC-type Fe3+-siderophore transport system, permease component
Locus tag: VIBHAR_06010
Name: fepC
Funciton: ABC-type Fe3+-siderophores transport system, ATPase component
Locus tag: VIBHAR_06011
Name: fepA
Funciton: TonB-dependent ferric achromobactin receptor
fepB
ABC-type Fe3+-siderophores transport systems, periplasmic component
fepD
ABC-type Fe3+-siderophore transport system, permease component
fepD
ABC-type Fe3+-siderophore transport system, permease component
fepC
ABC-type Fe3+-siderophores transport system, ATPase component
fepA
TonB-dependent ferric achromobactin receptor

Position: -24
Score: 4.9
Sequence: TAATAGGACTTATTCTCAATT
Locus tag: VIBHAR_02349
Name: VV1_2646
Funciton: ABC-type multidrug transport system, ATPase and permease component
VV1_2646
ABC-type multidrug transport system, ATPase and permease component

Position: -51
Score: 5.5
Sequence: AAATAAGAATAATTAGCACTA
Locus tag: VIBHAR_02715
Name: irpA
Funciton: Iron-regulated protein A precursor
irpA
Iron-regulated protein A precursor

Position: -118
Score: 5.2
Sequence: AAATAAGAATTGATGTCATTT
Position: -46
Score: 5.9
Sequence: AATTGAGAATAGTTATCAATT
Locus tag: VIBHAR_02726
Name: nrfB
Funciton: Cytochrome c-type protein NrfB precursor
Locus tag: VIBHAR_02725
Name: nfrC
Funciton: Putative nitrite reductase, Fe-S protein (NrfC)
Locus tag: VIBHAR_02724
Name: nfrC
Funciton: Putative nitrite reductase, Fe-S protein (NrfC)
Locus tag: VIBHAR_02723
Name: nrfD
Funciton: Putative nitrate reductase, formate dependent (NrfD)
nrfB
Cytochrome c-type protein NrfB precursor
nfrC
Putative nitrite reductase, Fe-S protein (NrfC)
nfrC
Putative nitrite reductase, Fe-S protein (NrfC)
nrfD
Putative nitrate reductase, formate dependent (NrfD)

Position: -80
Score: 5.9
Sequence: AAATGATAATTGATCTCATTT
Locus tag: VIBHAR_05127
Name: ptrB
Funciton: Protease II (EC 3.4.21.83)
Locus tag: VIBHAR_05128
Name: hutR
Funciton: TonB-dependent heme receptor HutR
Locus tag: VIBHAR_05129
Name: null
Funciton: hypothetical protein
Locus tag: VIBHAR_05130
Name: null
Funciton: hypothetical protein
Locus tag: VIBHAR_05131
Name: VCA0065
Funciton: Hypothetical with regulatory P domain of a subtilisin-like proprotein convertase
Locus tag: VIBHAR_05132
Name: VCA0065
Funciton: Hypothetical with regulatory P domain of a subtilisin-like proprotein convertase
Locus tag: VIBHAR_05133
Name: VCA0066
Funciton: Hypothetical protein in cluster with HutR, VCA0066 homolog
Locus tag: VIBHAR_05134
Name: VCA0066
Funciton: Hypothetical protein in cluster with HutR, VCA0066 homolog
Locus tag: VIBHAR_05135
Name: VCA0067
Funciton: Hypothetical protein in cluster with HutR, VCA0067 homolog
ptrB
Protease II (EC 3.4.21.83)
hutR
TonB-dependent heme receptor HutR
hypothetical protein
hypothetical protein
VCA0065
Hypothetical with regulatory P domain of a subtilisin-like proprotein convertase
VCA0065
Hypothetical with regulatory P domain of a subtilisin-like proprotein convertase
VCA0066
Hypothetical protein in cluster with HutR, VCA0066 homolog
VCA0066
Hypothetical protein in cluster with HutR, VCA0066 homolog
VCA0067
Hypothetical protein in cluster with HutR, VCA0067 homolog

Position: -79
Score: 5.6
Sequence: AATTGATAATTGATCTTATTT
Position: -34
Score: 5.3
Sequence: AGTTGATAATGATTAGCAATA
Locus tag: VIBHAR_05244
Name: tonB-hmu
Funciton: Periplasmic protein TonB involved in hemin uptake
Locus tag: VIBHAR_05243
Name: exbB-hmu
Funciton: TonB system transport protein ExbB involved in hemin uptake
Locus tag: VIBHAR_05242
Name: exbD-hmu
Funciton: TonB system transport protein ExbD involved in hemin uptake
Locus tag: VIBHAR_05241
Name: hmuT
Funciton: Hemin ABC transporter, periplasmic hemin-binding protein
Locus tag: VIBHAR_05240
Name: hmuU
Funciton: Hemin ABC transporter, permease component
Locus tag: VIBHAR_05239
Name: hmuV
Funciton: Hemin ABC transporter, ATP-binding subunit
tonB-hmu
Periplasmic protein TonB involved in hemin uptake
exbB-hmu
TonB system transport protein ExbB involved in hemin uptake
exbD-hmu
TonB system transport protein ExbD involved in hemin uptake
hmuT
Hemin ABC transporter, periplasmic hemin-binding protein
hmuU
Hemin ABC transporter, permease component
hmuV
Hemin ABC transporter, ATP-binding subunit

Position: -191
Score: 5.9
Sequence: AAATGGTAATAATTCTCATTA
Position: -165
Score: 5.5
Sequence: AAGTGAGAATTATTCGCAATA
Locus tag: VIBHAR_01860
Name: ppaC
Funciton: Manganese-dependent inorganic pyrophosphatase (EC 3.6.1.1)
ppaC
Manganese-dependent inorganic pyrophosphatase (EC 3.6.1.1)

Position: 4
Score: 4.4
Sequence: GAAAGAGAATTGTTATCAAAA
Locus tag: VIBHAR_06920
Name: VIBHAR_06920
Funciton: Siderophore-interacting protein ViuB
VIBHAR_06920
Siderophore-interacting protein ViuB

Position: -81
Score: 5.1
Sequence: AATTAATAATCATTCTCAAAA
Locus tag: VIBHAR_03251
Name: null
Funciton: hypothetical protein
hypothetical protein

Position: 4
Score: 4.4
Sequence: GAAAGAGAATTGTTATCAAAA
Locus tag: VIBHAR_06920
Name: viuB
Funciton: Siderophore-interacting protein ViuB
viuB
Siderophore-interacting protein ViuB

Position: -31
Score: 4.7
Sequence: GCATGATAACGGATCTCATTA
Locus tag: VIBHAR_06135
Name: vctP
Funciton: iron(III) ABC transporter, periplasmic iron-compound-binding protein
Locus tag: VIBHAR_06134
Name: vctD
Funciton: Iron(III) ABC transporter, permease protein
Locus tag: VIBHAR_06133
Name: vctB
Funciton: Iron(III) ABC transporter, permease protein
Locus tag: VIBHAR_06132
Name: vctC
Funciton: Iron(III) ABC transporter, ATP-binding protein
vctP
iron(III) ABC transporter, periplasmic iron-compound-binding protein
vctD
Iron(III) ABC transporter, permease protein
vctB
Iron(III) ABC transporter, permease protein
vctC
Iron(III) ABC transporter, ATP-binding protein

Position: -320
Score: 5.1
Sequence: TGATAGGATTAATTATCATTT
Locus tag: VIBHAR_02108
Name: vctD
Funciton: Iron(III) ABC transporter, permease protein
Locus tag: VIBHAR_02107
Name: vctB
Funciton: Iron(III) ABC transporter, permease protein
vctD
Iron(III) ABC transporter, permease protein
vctB
Iron(III) ABC transporter, permease protein

Position: -80
Score: 5.4
Sequence: TAACGCTAATTATTCTCATTA
Locus tag: VIBHAR_03054
Name: COG3016
Funciton: Conserved hypothetical iron-regulated protein
COG3016
Conserved hypothetical iron-regulated protein

Position: -173
Score: 5.2
Sequence: AAATGGTAATTACTATCATTC
Locus tag: VIBHAR_05788
Name: VCA0575
Funciton: Transcriptional regulator, LysR family
VCA0575
Transcriptional regulator, LysR family

Position: -41
Score: 6.1
Sequence: TATTGATAATAATTATCATTA
Position: -38
Score: 4.5
Sequence: TGATAATAATTATCATTATCT
Locus tag: VIBHAR_00162
Name: VC1572
Funciton: hypothetical protein
Locus tag: VIBHAR_00163
Name: fumC
Funciton: Fumarate hydratase class II (EC 4.2.1.2)
VC1572
hypothetical protein
fumC
Fumarate hydratase class II (EC 4.2.1.2)

Position: -78
Score: 5.5
Sequence: AACTAAGAATTATTATTATTA
Locus tag: VIBHAR_00530
Name: VC0074
Funciton: conserved hypothetical protein
VC0074
conserved hypothetical protein

Position: -97
Score: 5.4
Sequence: AAATGGTAATAGTTGTCATTT
Locus tag: VIBHAR_06761
Name: fhuE
Funciton: Putative ferrichrome-iron receptor
Locus tag: VIBHAR_06760
Name: PF11932
Funciton: hypothetical protein
Locus tag: VIBHAR_06759
Name: exbB1
Funciton: Biopolymer transport protein ExbB-related protein
Locus tag: VIBHAR_06758
Name: exbB2
Funciton: TonB system transport protein ExbB2
Locus tag: VIBHAR_06757
Name: exbD2
Funciton: TonB system transport protein ExbD2
Locus tag: VIBHAR_06756
Name: tonB
Funciton: Periplasmic protein TonB
Locus tag: VIBHAR_06755
Name: VC1543
Funciton: TPR domain protein, putative component of TonB system
fhuE
Putative ferrichrome-iron receptor
PF11932
hypothetical protein
exbB1
Biopolymer transport protein ExbB-related protein
exbB2
TonB system transport protein ExbB2
exbD2
TonB system transport protein ExbD2
tonB
Periplasmic protein TonB
VC1543
TPR domain protein, putative component of TonB system

Position: -46
Score: 5
Sequence: TAATGATAATGATAATGATTA
Position: -40
Score: 5.7
Sequence: TAATGATAATGATTATCTTTT
Locus tag: VIBHAR_07043
Name: VV21178
Funciton: ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
VV21178
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component

Position: -41
Score: 5.3
Sequence: AACTGATAAACGTTATCATTA
Locus tag: VIBHAR_03435
Name: fbpA
Funciton: Ferric iron ABC transporter, iron-binding protein
Locus tag: VIBHAR_03434
Name: fbpB
Funciton: Ferric iron ABC transporter, permease protein
Locus tag: VIBHAR_03433
Name: fbpC
Funciton: Ferric iron ABC transporter, ATP-binding protein
fbpA
Ferric iron ABC transporter, iron-binding protein
fbpB
Ferric iron ABC transporter, permease protein
fbpC
Ferric iron ABC transporter, ATP-binding protein

Position: -62
Score: 5.5
Sequence: TATTGCGAATAATTCTCACTT
Position: -36
Score: 5.9
Sequence: TAATGAGAATTATTACCATTT
Locus tag: VIBHAR_01859
Name: PF11449
Funciton: Predicted manganese transporter, 11 TMS
PF11449
Predicted manganese transporter, 11 TMS

Position: -66
Score: 5.3
Sequence: AGGTGATATTGATTCTCATTT
Locus tag: VIBHAR_04897
Name: mntH
Funciton: Manganese transport protein MntH
mntH
Manganese transport protein MntH

Position: -93
Score: 4.6
Sequence: AATTGAGAACCATTTACATTG
Locus tag: VIBHAR_06273
Name: VCA1041
Funciton: Phosphomannomutase
VCA1041
Phosphomannomutase

Position: -2
Score: 5.3
Sequence: AAATGATAATAGTTATAATCT
Locus tag: VIBHAR_05136
Name: torS
Funciton: Methyl-accepting chemotaxis protein
torS
Methyl-accepting chemotaxis protein

Position: -29
Score: 5.2
Sequence: AAATATCAATAATTATCATTT
Locus tag: VIBHAR_01763
Name: VIBHAR_01763
Funciton: Iron(III) dicitrate transport system, periplasmic iron-binding protein FecB (TC 3.A.1.14.1)
Locus tag: VIBHAR_01766
Name: VIBHAR_01766
Funciton: Ferrichrome transport ATP-binding protein FhuC (TC 3.A.1.14.3)
Locus tag: VIBHAR_01767
Name: VIBHAR_01767
Funciton: hypothetical protein
VIBHAR_01763
Iron(III) dicitrate transport system, periplasmic iron-binding protein FecB (TC 3.A.1.14.1)
VIBHAR_01766
Ferrichrome transport ATP-binding protein FhuC (TC 3.A.1.14.3)
VIBHAR_01767
hypothetical protein

Position: -48
Score: 4.9
Sequence: AATTGATATACATTCTCTTTT
Locus tag: VIBHAR_06888
Name: null
Funciton: hypothetical protein
hypothetical protein

Position: -58
Score: 4.5
Sequence: TAACAAGAACGATTCTTGTTT
Locus tag: VIBHAR_00053
Name: bfd
Funciton: Bacterioferritin-associated ferredoxin
Locus tag: VIBHAR_00052
Name: bfr
Funciton: Bacterioferritin
bfd
Bacterioferritin-associated ferredoxin
bfr
Bacterioferritin
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