Regulon of Fur in Vibrio cholerae O1 biovar eltor str. N16961
| Regulator type: | Transcription factor |
| TF locus tag: | VC2106 |
| Regulator family: | FUR |
| Regulation mode: | repressor (activator) |
| Biological process: | Iron homeostasis |
| Effector: | Iron ion, (Fe2+) |
| Regulog: | Fur - Vibrionales |
| Statistics of regulated genes: | |
| - Genes | 63 |
| - Operons | 32 |
| Visualization: | |
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Allows to visualize regulon content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Vibrionales
- By trascription factor - FUR
- By TF family - FUR
- By effector - Iron ion, (Fe2+)
- By pathway - Iron homeostasis
| Locus Tag | Name | Function | |
|---|---|---|---|
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Position: -107
Score: 5.3 Sequence: TAATAATAGCAATTATCAATT
Locus tag: VCA0909
Name: hutW Funciton: Radical SAM family protein HutW, similar to coproporphyrinogen III oxidase, oxygen-independent, associated with heme uptake
Locus tag: VCA0908
Name: huvX Funciton: Putative heme iron utilization protein
Locus tag: VCA0907
Name: hutZ Funciton: Pyridoxamine 5'-phosphate oxidase-related putative heme iron utilization protein # hutZ |
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hutW
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Radical SAM family protein HutW, similar to coproporphyrinogen III oxidase, oxygen-independent, associated with heme uptake
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huvX
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Putative heme iron utilization protein
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hutZ
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Pyridoxamine 5'-phosphate oxidase-related putative heme iron utilization protein # hutZ
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Position: -23
Score: 4.4 Sequence: TGTTGAGATAAATTCTCAACA
Position: 10
Score: 4.9 Sequence: ATTTGAGATTCATTATCATCT
Locus tag: VC0091
Name: COG3315 Funciton: O-Methyltransferase involved in polyketide biosynthesis |
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COG3315
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O-Methyltransferase involved in polyketide biosynthesis
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Position: -93
Score: 5.9 Sequence: AATTGATAATGATTATTATTA
Position: -90
Score: 4.4 Sequence: TGATAATGATTATTATTAACT
Locus tag: VC2209
Name: vibF Funciton: nonribosomal peptide synthetase VibF |
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vibF
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nonribosomal peptide synthetase VibF
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Position: -37
Score: 6 Sequence: TAATGATATTAATTATCATTA
Locus tag: VC2694
Name: sodA Funciton: Manganese superoxide dismutase (EC 1.15.1.1) |
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sodA
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Manganese superoxide dismutase (EC 1.15.1.1)
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Position: -53
Score: 5.8 Sequence: ACATGATAATAATTATCAATT
Locus tag: VC1009
Name: PF10952 Funciton: Protein of unknown function (DUF2753) |
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PF10952
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Protein of unknown function (DUF2753)
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Position: -34
Score: 6 Sequence: AATTAAGAATAATTATCATTT
Locus tag: VC0475
Name: irgA Funciton: TonB-dependent receptor; Enterobactin receptor IrgA |
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irgA
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TonB-dependent receptor; Enterobactin receptor IrgA
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Position: -214
Score: 4.8 Sequence: AAATAAAAATGTTTTTCATTG
Position: -196
Score: 4.9 Sequence: TTGTAATATTGATTCTCATTT
Locus tag: VC0775
Name: vibH Funciton: Amide synthase component of siderophore synthetase # Vibriobactin-specific, VibH |
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vibH
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Amide synthase component of siderophore synthetase # Vibriobactin-specific, VibH
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Position: -60
Score: 5.7 Sequence: AAATGATAGCAATTATCATTA
Locus tag: VCA0576
Name: null Funciton: TonB-dependent heme and hemoglobin receptor HutA; TonB-dependent hemin , ferrichrome receptor |
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TonB-dependent heme and hemoglobin receptor HutA; TonB-dependent hemin , ferrichrome receptor
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Position: -167
Score: 6.1 Sequence: AAATGATAATTGTTATTATTT
Locus tag: VC0771
Name: VC0771 Funciton: Isochorismatase (EC 3.3.2.1) of siderophore biosynthesis # Vibriobactin-specific, VibB |
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VC0771
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Isochorismatase (EC 3.3.2.1) of siderophore biosynthesis # Vibriobactin-specific, VibB
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Position: -140
Score: 5.5 Sequence: TAATGATATACATTCTCATTT
Locus tag: VC2210
Name: viuB Funciton: Vibriobactin utilization protein ViuB |
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viuB
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Vibriobactin utilization protein ViuB
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Position: -114
Score: 4.7 Sequence: AAATGGAAATTGCTTGCATTT
Position: -91
Score: 5.7 Sequence: TAATAAAAACTATTCTCATTT
Locus tag: VC0773
Name: VC0773 Funciton: Isochorismate synthase (EC 5.4.4.2) of siderophore biosynthesis # Vibriobactin-specific
Locus tag: VC0772
Name: VC0772 Funciton: 2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) # Vibriobactin-specific, VibE |
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VC0773
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Isochorismate synthase (EC 5.4.4.2) of siderophore biosynthesis # Vibriobactin-specific
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VC0772
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2,3-dihydroxybenzoate-AMP ligase (EC 2.7.7.58) # Vibriobactin-specific, VibE
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Position: -46
Score: 5.1 Sequence: TAATAGTAATATTTCTTATTA
Locus tag: VC2078
Name: feoA Funciton: Ferrous iron transport protein A
Locus tag: VC2077
Name: feoB Funciton: Ferrous iron transport protein B
Locus tag: VC2076
Name: feoC Funciton: Ferrous iron transport protein C |
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feoA
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Ferrous iron transport protein A
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feoB
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Ferrous iron transport protein B
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feoC
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Ferrous iron transport protein C
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Position: -54
Score: 5.2 Sequence: AATTGAGAAAGATTCGCAATT
Position: -24
Score: 4.5 Sequence: TAATTAAGATAATTATCACTA
Locus tag: VC0200
Name: fhuA Funciton: TonB-dependent outer membrane receptor for iron siderophores
Locus tag: VC0201
Name: fhuC Funciton: Ferrichrome transport ATP-binding protein FhuC
Locus tag: VC0202
Name: fhuD Funciton: Ferrichrome-binding periplasmic protein precursor (TC 3.A.1.14.3)
Locus tag: VC0203
Name: fhuB Funciton: Ferrichrome transport system permease protein FhuB |
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fhuA
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TonB-dependent outer membrane receptor for iron siderophores
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fhuC
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Ferrichrome transport ATP-binding protein FhuC
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fhuD
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Ferrichrome-binding periplasmic protein precursor (TC 3.A.1.14.3)
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fhuB
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Ferrichrome transport system permease protein FhuB
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Position: -2
Score: 5.8 Sequence: AAATGATAATAATTTGCAATT
Locus tag: VC1264
Name: irpA Funciton: Iron-regulated protein A precursor |
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irpA
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Iron-regulated protein A precursor
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Position: -143
Score: 5.1 Sequence: AGTTGAGAACTATTCGCAATT
Locus tag: VC1687
Name: ppaC Funciton: Manganese-dependent inorganic pyrophosphatase (EC 3.6.1.1) |
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ppaC
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Manganese-dependent inorganic pyrophosphatase (EC 3.6.1.1)
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Position: 20
Score: 4.9 Sequence: AATTAATAATTATTCTCAAGG
Locus tag: VC0877
Name: null Funciton: hypothetical protein
Locus tag: VC0876
Name: null Funciton: conserved hypothetical protein |
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hypothetical protein
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conserved hypothetical protein
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Position: 28
Score: 4.9 Sequence: TAATGAGAATAAGTATCAAAA
Locus tag: VCA0227
Name: vctP Funciton: iron(III) ABC transporter, periplasmic iron-compound-binding protein
Locus tag: VCA0228
Name: vctD Funciton: Iron(III) ABC transporter, permease protein
Locus tag: VCA0229
Name: vctB Funciton: Iron(III) ABC transporter, permease protein
Locus tag: VCA0230
Name: vctC Funciton: Iron(III) ABC transporter, ATP-binding protein |
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vctP
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iron(III) ABC transporter, periplasmic iron-compound-binding protein
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vctD
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Iron(III) ABC transporter, permease protein
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vctB
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Iron(III) ABC transporter, permease protein
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vctC
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Iron(III) ABC transporter, ATP-binding protein
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Position: -76
Score: 5.7 Sequence: AAATGATAATTGATCTTATTT
Locus tag: VCA0063
Name: ptrB Funciton: Protease II (EC 3.4.21.83)
Locus tag: VCA0064
Name: hutR Funciton: TonB-dependent heme receptor HutR
Locus tag: VCA0065
Name: VCA0065 Funciton: Hypothetical with regulatory P domain of a subtilisin-like proprotein convertase
Locus tag: VCA0066
Name: VCA0066 Funciton: Hypothetical protein in cluster with HutR, VCA0066 homolog
Locus tag: VCA0067
Name: VCA0067 Funciton: Hypothetical protein in cluster with HutR, VCA0067 homolog |
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ptrB
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Protease II (EC 3.4.21.83)
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hutR
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TonB-dependent heme receptor HutR
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VCA0065
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Hypothetical with regulatory P domain of a subtilisin-like proprotein convertase
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VCA0066
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Hypothetical protein in cluster with HutR, VCA0066 homolog
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VCA0067
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Hypothetical protein in cluster with HutR, VCA0067 homolog
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Position: -178
Score: 5.7 Sequence: TAATGATAATTGCTATCATTT
Locus tag: VCA0575
Name: VCA0575 Funciton: Transcriptional regulator, LysR family |
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VCA0575
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Transcriptional regulator, LysR family
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Position: -40
Score: 5.6 Sequence: ATGTGATAATAATTATCATTT
Locus tag: VC1572
Name: VC1572 Funciton: hypothetical protein
Locus tag: VC1573
Name: fumC Funciton: Fumarate hydratase class II (EC 4.2.1.2) |
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VC1572
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hypothetical protein
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fumC
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Fumarate hydratase class II (EC 4.2.1.2)
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Position: -29
Score: 4.5 Sequence: GTCTGAGAATAATTCGTATTT
Locus tag: VC0074
Name: VC0074 Funciton: conserved hypothetical protein |
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VC0074
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conserved hypothetical protein
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Position: -170
Score: 5.3 Sequence: AATTGATAATTGCTATTATTA
Locus tag: VCA0910
Name: tonB-hmu Funciton: Periplasmic protein TonB involved in hemin uptake
Locus tag: VCA0911
Name: exbB-hmu Funciton: TonB system transport protein ExbB involved in hemin uptake
Locus tag: VCA0912
Name: exbD-hmu Funciton: TonB system transport protein ExbD involved in hemin uptake
Locus tag: VCA0913
Name: hmuT Funciton: Hemin ABC transporter, periplasmic hemin-binding protein
Locus tag: VCA0914
Name: hmuU Funciton: Hemin ABC transporter, permease component
Locus tag: VCA0915
Name: hmuV Funciton: Hemin ABC transporter, ATP-binding subunit |
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tonB-hmu
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Periplasmic protein TonB involved in hemin uptake
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exbB-hmu
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TonB system transport protein ExbB involved in hemin uptake
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exbD-hmu
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TonB system transport protein ExbD involved in hemin uptake
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hmuT
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Hemin ABC transporter, periplasmic hemin-binding protein
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hmuU
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Hemin ABC transporter, permease component
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hmuV
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Hemin ABC transporter, ATP-binding subunit
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Position: -58
Score: 4.8 Sequence: TAATGAGAGCGTTTCTCAATA
Locus tag: VC1548
Name: PF11932 Funciton: hypothetical protein
Locus tag: VC1547
Name: exbB1 Funciton: Biopolymer transport protein ExbB-related protein
Locus tag: VC1546
Name: exbB2 Funciton: TonB system transport protein ExbB2
Locus tag: VC1544
Name: tonB Funciton: Periplasmic protein TonB
Locus tag: VC1543
Name: VC1543 Funciton: TPR domain protein, putative component of TonB system |
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PF11932
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hypothetical protein
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exbB1
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Biopolymer transport protein ExbB-related protein
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exbB2
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TonB system transport protein ExbB2
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tonB
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Periplasmic protein TonB
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VC1543
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TPR domain protein, putative component of TonB system
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Position: -2
Score: 4.9 Sequence: AAATGAGAATCAATATTACAA
Position: 16
Score: 4.8 Sequence: CAATGAAAAACATTTTTATTT
Locus tag: VC0776
Name: viuP Funciton: Ferric vibriobactin, enterobactin transport system, substrate-binding protein ViuP (TC 3.A.1.14.6)
Locus tag: VC0777
Name: viuD Funciton: Ferric vibriobactin, enterobactin transport system, permease protein ViuD (TC 3.A.1.14.6)
Locus tag: VC0778
Name: viuG Funciton: Ferric vibriobactin, enterobactin transport system, permease protein ViuG (TC 3.A.1.14.6) |
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viuP
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Ferric vibriobactin, enterobactin transport system, substrate-binding protein ViuP (TC 3.A.1.14.6)
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viuD
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Ferric vibriobactin, enterobactin transport system, permease protein ViuD (TC 3.A.1.14.6)
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viuG
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Ferric vibriobactin, enterobactin transport system, permease protein ViuG (TC 3.A.1.14.6)
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Position: 4
Score: 5.2 Sequence: GATTGATAAAGGTTATCATTA
Locus tag: VC0608
Name: fbpA Funciton: Ferric iron ABC transporter, iron-binding protein
Locus tag: VC0609
Name: fbpB Funciton: Ferric iron ABC transporter, permease protein
Locus tag: VC0610
Name: fbpC Funciton: Ferric iron ABC transporter, ATP-binding protein |
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fbpA
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Ferric iron ABC transporter, iron-binding protein
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fbpB
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Ferric iron ABC transporter, permease protein
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fbpC
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Ferric iron ABC transporter, ATP-binding protein
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Position: -97
Score: 5.7 Sequence: AAATGAGAATAGTTTTTATTA
Position: -74
Score: 4.7 Sequence: AAATGCAAGCAATTTCCATTT
Locus tag: VC0774
Name: VC0774 Funciton: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (EC 1.3.1.28) # Vibriobactin-specific, VibA |
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VC0774
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2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (EC 1.3.1.28) # Vibriobactin-specific, VibA
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Position: -41
Score: 5.4 Sequence: TAACGATAATTATTCTTAATA
Locus tag: VCA0068
Name: torS Funciton: Methyl-accepting chemotaxis protein |
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torS
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Methyl-accepting chemotaxis protein
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Position: -131
Score: 6 Sequence: AAATGATAATTATTCTTAATT
Locus tag: VC0474
Name: irgB Funciton: Iron-regulated virulence regulatory protein irgB |
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irgB
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Iron-regulated virulence regulatory protein irgB
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Position: -54
Score: 4.9 Sequence: AAATAAGAGTGATTCTCTTTT
Locus tag: VC0364
Name: bfd Funciton: Bacterioferritin-associated ferredoxin
Locus tag: VC0365
Name: bfr Funciton: Bacterioferritin |
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bfd
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Bacterioferritin-associated ferredoxin
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bfr
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Bacterioferritin
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Position: -24
Score: 5.1 Sequence: AATTGCGAATAGTTCTCAACT
Position: 1
Score: 4.9 Sequence: TGTCGATAATAATTCTCATTC
Locus tag: VC1688
Name: PF11449 Funciton: Predicted manganese transporter, 11 TMS |
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PF11449
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Predicted manganese transporter, 11 TMS
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Position: -290
Score: 5 Sequence: AAATGAGAATGCTTTACATTT
Locus tag: VC2211
Name: viuA Funciton: Ferric aerobactin receptor, TonB-dependent |
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viuA
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Ferric aerobactin receptor, TonB-dependent
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Position: -61
Score: 5.2 Sequence: TTTTGAGAATAAATATCAATT
Locus tag: VCA1041
Name: VCA1041 Funciton: Phosphomannomutase |
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VCA1041
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Phosphomannomutase
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
|
Regulatory Sites | [ FASTA format ] | DOWNLOAD |