Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of IscR in Silicibacter TM1040

Properties
Regulator type: Transcription factor
TF locus tag: TM1040_1240
Regulator family: Rrf2
Regulation mode: repressor (activator)
Biological process: Iron-sulfur cluster biogenesis; Iron homeostasis
Effector: Iron-sulfur cluster redox state; Iron ion, (Fe2+)
Regulog: IscR - Rhodobacterales
Statistics of regulated genes:
- Genes 26
- Operons 7
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 125 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -116
Score: 4.5
Sequence: TCCGACAAAAATACTAGGG
Locus tag: TM1040_2633
Name: TM1040_2633
Funciton: hypothetical protein
TM1040_2633
hypothetical protein

Position: -143
Score: 3.9
Sequence: CTTGACAGATTTAATAAAT
Locus tag: TM1040_0347
Name: hmuR
Funciton: TonB-dependent hemin , ferrichrome receptor
Locus tag: TM1040_0348
Name: Mlr1156
Funciton: Mlr1156 protein
Locus tag: TM1040_0349
Name: exbB
Funciton: Ferric siderophore transport system, biopolymer transport protein ExbB
Locus tag: TM1040_0350
Name: exbD1
Funciton: Ferric siderophore transport system, periplasmic binding protein ExbD
Locus tag: TM1040_0351
Name: exbD2
Funciton: Ferric siderophore transport system, periplasmic binding protein ExbD
Locus tag: TM1040_0352
Name: tonB
Funciton: Ferric siderophore transport system, periplasmic binding protein TonB
hmuR
TonB-dependent hemin , ferrichrome receptor
Mlr1156
Mlr1156 protein
exbB
Ferric siderophore transport system, biopolymer transport protein ExbB
exbD1
Ferric siderophore transport system, periplasmic binding protein ExbD
exbD2
Ferric siderophore transport system, periplasmic binding protein ExbD
tonB
Ferric siderophore transport system, periplasmic binding protein TonB

Position: -50
Score: 3.7
Sequence: TCCGACAAAAATGCTTGAA
Locus tag: TM1040_0122
Name: fbpB
Funciton: Ferric iron ABC transporter, permease protein
fbpB
Ferric iron ABC transporter, permease protein

Position: -103
Score: 4.1
Sequence: CCTGATCAAAACAGTCCGA
Position: -71
Score: 4.2
Sequence: GCTTATTCTTTTACTCGGA
Locus tag: TM1040_2200
Name: bfd
Funciton: Bacterioferritin-associated ferredoxin
Locus tag: TM1040_2201
Name: bfr
Funciton: Bacterioferritin (cytochrome b1)
Locus tag: TM1040_2202
Name: COG3488
Funciton: Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites
Locus tag: TM1040_2203
Name: COG3489
Funciton: Predicted periplasmic lipoprotein
Locus tag: TM1040_2204
Name: COG3490
Funciton: Uncharacterised conserved protein UCP028101
bfd
Bacterioferritin-associated ferredoxin
bfr
Bacterioferritin (cytochrome b1)
COG3488
Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites
COG3489
Predicted periplasmic lipoprotein
COG3490
Uncharacterised conserved protein UCP028101

Position: -258
Score: 4.7
Sequence: TCTGACCAAATAAATCAGG
Locus tag: TM1040_2198
Name: hemP
Funciton: Hemin uptake protein HemP
Locus tag: TM1040_2199
Name: irpA
Funciton: Iron-regulated protein A precursor
hemP
Hemin uptake protein HemP
irpA
Iron-regulated protein A precursor

Position: -137
Score: 3.9
Sequence: CTTGACGAATTTTATCCGG
Locus tag: TM1040_1240
Name: iscR
Funciton: Iron-sulfur cluster regulator IscR, Rrf2 family
Locus tag: TM1040_1241
Name: iscS
Funciton: Cysteine desulfurase (EC 2.8.1.7)
Locus tag: TM1040_1242
Name: sufB
Funciton: Iron-sulfur cluster assembly protein SufB
Locus tag: TM1040_1243
Name: RSP_0439
Funciton: protein of unknown function DUF74
Locus tag: TM1040_1244
Name: Jann_2362
Funciton: SAM-dependent methyltransferases
Locus tag: TM1040_1245
Name: sufC
Funciton: Iron-sulfur cluster assembly ATPase protein SufC
Locus tag: TM1040_1246
Name: sufD
Funciton: Iron-sulfur cluster assembly protein SufD
Locus tag: TM1040_1247
Name: RSP_0433
Funciton: hypothetical protein
Locus tag: TM1040_1248
Name: null
Funciton: hypothetical protein
Locus tag: TM1040_1249
Name: sufS
Funciton: Cysteine desulfurase (EC 2.8.1.7), SufS subfamily
iscR
Iron-sulfur cluster regulator IscR, Rrf2 family
iscS
Cysteine desulfurase (EC 2.8.1.7)
sufB
Iron-sulfur cluster assembly protein SufB
RSP_0439
protein of unknown function DUF74
Jann_2362
SAM-dependent methyltransferases
sufC
Iron-sulfur cluster assembly ATPase protein SufC
sufD
Iron-sulfur cluster assembly protein SufD
RSP_0433
hypothetical protein
hypothetical protein
sufS
Cysteine desulfurase (EC 2.8.1.7), SufS subfamily

Position: -126
Score: 5
Sequence: TCTGACTGAATTTATCGGA
Locus tag: TM1040_0124
Name: fbpA
Funciton: Ferric iron ABC transporter, iron-binding protein
fbpA
Ferric iron ABC transporter, iron-binding protein
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