Regulon of IscR in Roseovarius sp. 217

Properties
Regulator type:	Transcription factor
TF locus tag:	ROS217_20542
Regulator family:	Rrf2
Regulation mode:	repressor (activator)
Biological process:	Iron-sulfur cluster biogenesis; Iron homeostasis
Effector:	Iron-sulfur cluster redox state; Iron ion, (Fe2+)
Regulog:	IscR - Rhodobacterales
Statistics of regulated genes:
- Genes	25
- Operons	8
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 125 sites [see more]

Member of regulog collections

By trascription factor - IscR
By taxonomy - Rhodobacterales
By TF family - Rrf2
By effector - Iron-sulfur cluster redox state
By effector - Iron ion, (Fe2+)
By pathway - Iron-sulfur cluster biogenesis
By pathway - Iron homeostasis

Regulated operons
	Locus Tag	Name	Function
Position: -36 Score: 4.1 Sequence: CCCGATAGATTTGATCGGA Locus tag: ROS217_20592 Name: fbpC Funciton: Ferric iron ABC transporter, ATP-binding protein
	ROS217_20592	fbpC	Ferric iron ABC transporter, ATP-binding protein
Position: -165 Score: 4.1 Sequence: CCTGATGTAATTTGTCAAC Locus tag: ROS217_22877 Name: araX Funciton: Iron-regulated transcriptional regulator, AraC family
	ROS217_22877	araX	Iron-regulated transcriptional regulator, AraC family
Position: -198 Score: 4.4 Sequence: CTTGACTCTTTTACTCATA Locus tag: ROS217_17442 Name: hmuR Funciton: TonB-dependent hemin , ferrichrome receptor
	ROS217_17442	hmuR	TonB-dependent hemin , ferrichrome receptor
Position: -30 Score: 4.7 Sequence: CCTGAGTTAAAGAGTCGGA Locus tag: ROS217_22882 Name: fhuA Funciton: Ferric hydroxamate outer membrane receptor FhuA Locus tag: ROS217_22887 Name: fhuD Funciton: Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), periplasmic substrate binding protein FhuD Locus tag: ROS217_22892 Name: fhuB Funciton: Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), permease component FhuB Locus tag: ROS217_22897 Name: fhuC Funciton: Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), ATP-binding protein FhuC
	ROS217_22882	fhuA	Ferric hydroxamate outer membrane receptor FhuA
	ROS217_22887	fhuD	Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), periplasmic substrate binding protein FhuD
	ROS217_22892	fhuB	Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), permease component FhuB
	ROS217_22897	fhuC	Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), ATP-binding protein FhuC
Position: -70 Score: 4.8 Sequence: ATTGACTCTTTTAGTCAGA Position: -38 Score: 3.8 Sequence: CCCCATCAAATCACTCGGA Locus tag: ROS217_23057 Name: fbpA Funciton: Ferric iron ABC transporter, iron-binding protein
	ROS217_23057	fbpA	Ferric iron ABC transporter, iron-binding protein
Position: -120 Score: 3.5 Sequence: CTTGACGACTTCGCTCGGG Locus tag: ROS217_20542 Name: iscR Funciton: Iron-sulfur cluster regulator IscR, Rrf2 family Locus tag: ROS217_20537 Name: iscS Funciton: Cysteine desulfurase (EC 2.8.1.7) Locus tag: ROS217_20532 Name: sufB Funciton: Iron-sulfur cluster assembly protein SufB Locus tag: ROS217_20527 Name: RSP_0439 Funciton: protein of unknown function DUF74 Locus tag: ROS217_20522 Name: null Funciton: hypothetical protein Locus tag: ROS217_20517 Name: sufC Funciton: Iron-sulfur cluster assembly ATPase protein SufC Locus tag: ROS217_20512 Name: sufD Funciton: Iron-sulfur cluster assembly protein SufD Locus tag: ROS217_20507 Name: RSP_0433 Funciton: hypothetical protein Locus tag: ROS217_20502 Name: null Funciton: hypothetical protein Locus tag: ROS217_20497 Name: sufS Funciton: Cysteine desulfurase (EC 2.8.1.7), SufS subfamily
	ROS217_20542	iscR	Iron-sulfur cluster regulator IscR, Rrf2 family
	ROS217_20537	iscS	Cysteine desulfurase (EC 2.8.1.7)
	ROS217_20532	sufB	Iron-sulfur cluster assembly protein SufB
	ROS217_20527	RSP_0439	protein of unknown function DUF74
	ROS217_20522		hypothetical protein
	ROS217_20517	sufC	Iron-sulfur cluster assembly ATPase protein SufC
	ROS217_20512	sufD	Iron-sulfur cluster assembly protein SufD
	ROS217_20507	RSP_0433	hypothetical protein
	ROS217_20502		hypothetical protein
	ROS217_20497	sufS	Cysteine desulfurase (EC 2.8.1.7), SufS subfamily
Position: -147 Score: 4.6 Sequence: GCCTACTAAATCAGTCAAC Locus tag: ROS217_10107 Name: irpA Funciton: Iron-regulated protein A precursor Locus tag: ROS217_10102 Name: hmuX Funciton: hypothetical porin Locus tag: ROS217_10097 Name: COG3488 Funciton: Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites Locus tag: ROS217_10092 Name: COG3489 Funciton: Predicted periplasmic lipoprotein Locus tag: ROS217_10087 Name: COG3490 Funciton: Uncharacterised conserved protein UCP028101
	ROS217_10107	irpA	Iron-regulated protein A precursor
	ROS217_10102	hmuX	hypothetical porin
	ROS217_10097	COG3488	Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites
	ROS217_10092	COG3489	Predicted periplasmic lipoprotein
	ROS217_10087	COG3490	Uncharacterised conserved protein UCP028101
Position: -152 Score: 4.2 Sequence: TCTGATCAAAAGAATCGGA Position: -124 Score: 4.7 Sequence: CCTTATTAATTAAGTCAGA Locus tag: ROS217_23865 Name: hemP Funciton: Hemin uptake protein HemP Locus tag: ROS217_23860 Name: null Funciton: hypothetical protein
	ROS217_23865	hemP	Hemin uptake protein HemP
	ROS217_23860		hypothetical protein

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of IscR in Roseovarius sp. 217

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --