Regulon of IscR in Roseovarius nubinhibens ISM

Properties
Regulator type:	Transcription factor
TF locus tag:	ISM_16015
Regulator family:	Rrf2
Regulation mode:	repressor (activator)
Biological process:	Iron-sulfur cluster biogenesis; Iron homeostasis
Effector:	Iron-sulfur cluster redox state; Iron ion, (Fe2+)
Regulog:	IscR - Rhodobacterales
Statistics of regulated genes:
- Genes	19
- Operons	9
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 125 sites [see more]

Member of regulog collections

By trascription factor - IscR
By taxonomy - Rhodobacterales
By TF family - Rrf2
By effector - Iron-sulfur cluster redox state
By effector - Iron ion, (Fe2+)
By pathway - Iron-sulfur cluster biogenesis
By pathway - Iron homeostasis

Regulated operons
	Locus Tag	Name	Function
Position: -46 Score: 4.5 Sequence: CCCGAGTGAATTGATCGGA Locus tag: ISM_15910 Name: fbpC Funciton: Ferric iron ABC transporter, ATP-binding protein
	ISM_15910	fbpC	Ferric iron ABC transporter, ATP-binding protein
Position: -132 Score: 4 Sequence: TCCGACTATTTCATTTAGG Locus tag: ISM_04265 Name: Mlr1156 Funciton: Mlr1156 protein Locus tag: ISM_04260 Name: exbB Funciton: Ferric siderophore transport system, biopolymer transport protein ExbB Locus tag: ISM_04255 Name: exbD1 Funciton: Ferric siderophore transport system, periplasmic binding protein ExbD Locus tag: ISM_04250 Name: exbD2 Funciton: Ferric siderophore transport system, periplasmic binding protein ExbD Locus tag: ISM_04245 Name: tonB Funciton: Ferric siderophore transport system, periplasmic binding protein TonB
	ISM_04265	Mlr1156	Mlr1156 protein
	ISM_04260	exbB	Ferric siderophore transport system, biopolymer transport protein ExbB
	ISM_04255	exbD1	Ferric siderophore transport system, periplasmic binding protein ExbD
	ISM_04250	exbD2	Ferric siderophore transport system, periplasmic binding protein ExbD
	ISM_04245	tonB	Ferric siderophore transport system, periplasmic binding protein TonB
Position: -117 Score: 4.9 Sequence: CCTGAGTAAAAGACTCAGG Locus tag: ISM_00940 Name: OB2597_05460 Funciton: TonB-dependent hemin, ferrichrome receptor
	ISM_00940	OB2597_05460	TonB-dependent hemin, ferrichrome receptor
Position: -100 Score: 4.1 Sequence: CTTGACTTTTTGCCTCAGG Locus tag: ISM_05670 Name: ISM_05670 Funciton: Outer membrane receptor proteins, mostly Fe transport
	ISM_05670	ISM_05670	Outer membrane receptor proteins, mostly Fe transport
Position: -81 Score: 4.9 Sequence: TCCGACTCTTTTTGTCAGA Locus tag: ISM_15940 Name: SKA53_15391 Funciton: hypothetical protein Locus tag: ISM_15945 Name: TM1040_2633 Funciton: hypothetical protein
	ISM_15940	SKA53_15391	hypothetical protein
	ISM_15945	TM1040_2633	hypothetical protein
Position: -157 Score: 4.4 Sequence: CTTGACAGTTTTAGTCTGA Locus tag: ISM_04235 Name: hmuR Funciton: TonB-dependent hemin , ferrichrome receptor
	ISM_04235	hmuR	TonB-dependent hemin , ferrichrome receptor
Position: -138 Score: 5.4 Sequence: CTTGACTAAATTAGTCGGA Position: -104 Score: 5.2 Sequence: TCCGAGTATTTTAGTCGGA Locus tag: ISM_05125 Name: fbpA Funciton: Ferric iron ABC transporter, iron-binding protein
	ISM_05125	fbpA	Ferric iron ABC transporter, iron-binding protein
Position: -82 Score: 4.9 Sequence: CCCGAGTATTTCACTCAGG Locus tag: ISM_04365 Name: irpA Funciton: Iron-regulated protein A precursor Locus tag: ISM_04360 Name: COG3488 Funciton: Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites Locus tag: ISM_04355 Name: COG3489 Funciton: Predicted periplasmic lipoprotein Locus tag: ISM_04350 Name: COG3490 Funciton: Uncharacterised conserved protein UCP028101
	ISM_04365	irpA	Iron-regulated protein A precursor
	ISM_04360	COG3488	Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites
	ISM_04355	COG3489	Predicted periplasmic lipoprotein
	ISM_04350	COG3490	Uncharacterised conserved protein UCP028101
Position: -205 Score: 5.2 Sequence: TCTGACTAAAAAAGTCGGA Position: -178 Score: 4.8 Sequence: TCTGACAGAATAAATCAGA Locus tag: ISM_01000 Name: hemP Funciton: Hemin uptake protein HemP Locus tag: ISM_00995 Name: bfd Funciton: Bacterioferritin-associated ferredoxin Locus tag: ISM_00990 Name: bfr Funciton: Bacterioferritin (cytochrome b1)
	ISM_01000	hemP	Hemin uptake protein HemP
	ISM_00995	bfd	Bacterioferritin-associated ferredoxin
	ISM_00990	bfr	Bacterioferritin (cytochrome b1)

Export
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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of IscR in Roseovarius nubinhibens ISM

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --