Regulon of IscR in Rhodobacter sphaeroides 2.4.1

Properties
Regulator type:	Transcription factor
TF locus tag:	RSP_0443
Regulator family:	Rrf2
Regulation mode:	repressor (activator)
Biological process:	Iron-sulfur cluster biogenesis; Iron homeostasis
Effector:	Iron-sulfur cluster redox state; Iron ion, (Fe2+)
Regulog:	IscR - Rhodobacterales
Statistics of regulated genes:
- Genes	27
- Operons	8
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 125 sites [see more]

Member of regulog collections

By trascription factor - IscR
By taxonomy - Rhodobacterales
By TF family - Rrf2
By effector - Iron-sulfur cluster redox state
By effector - Iron ion, (Fe2+)
By pathway - Iron-sulfur cluster biogenesis
By pathway - Iron homeostasis

Regulated operons
	Locus Tag	Name	Function
Position: -80 Score: 4.5 Sequence: GTTGACTGATAGACTCAGC Position: -20 Score: 3.7 Sequence: CCTGACAAAAGAGGTCACA Locus tag: RSP_2913 Name: fbpA Funciton: Ferric iron ABC transporter, iron-binding protein
	RSP_2913	fbpA	Ferric iron ABC transporter, iron-binding protein
Position: -70 Score: 4.3 Sequence: GCCGAGCGATATTGTCGGG Locus tag: RSP_4275 Name: fecI Funciton: RNA polymerase sigma-70 factor, ECF subfamily Locus tag: RSP_4274 Name: fecR Funciton: FecR protein Locus tag: RSP_4273 Name: fhuA Funciton: TonB-dependent receptor protein Locus tag: RSP_4272 Name: fhuD Funciton: ABC cobalamin/Fe3+-siderophore transporter, periplasmic ligand binding protein Locus tag: RSP_4271 Name: fhuB Funciton: ABC cobalamin/Fe3+-siderophore transporter, inner membrane subunit Locus tag: RSP_7397 Name: fhuC Funciton: Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), ATP-binding protein FhuC
	RSP_4275	fecI	RNA polymerase sigma-70 factor, ECF subfamily
	RSP_4274	fecR	FecR protein
	RSP_4273	fhuA	TonB-dependent receptor protein
	RSP_4272	fhuD	ABC cobalamin/Fe3+-siderophore transporter, periplasmic ligand binding protein
	RSP_4271	fhuB	ABC cobalamin/Fe3+-siderophore transporter, inner membrane subunit
	RSP_7397	fhuC	Ferric hydroxamate ABC transporter (TC 3.A.1.14.3), ATP-binding protein FhuC
Position: -134 Score: 4 Sequence: CTTGACTGTTTTCGTAAAC Locus tag: RSP_0920 Name: exbB Funciton: Biopolymer transport protein, ExbB Locus tag: RSP_0921 Name: exbD Funciton: Biopolymer transport protein ExbD/TolR Locus tag: RSP_0922 Name: tonB Funciton: Ferric siderophore transport system, periplasmic binding protein TonB
	RSP_0920	exbB	Biopolymer transport protein, ExbB
	RSP_0921	exbD	Biopolymer transport protein ExbD/TolR
	RSP_0922	tonB	Ferric siderophore transport system, periplasmic binding protein TonB
Position: -204 Score: 4.6 Sequence: TCCGACAAGAACAGTCGGA Locus tag: RSP_3417 Name: RSP_3417 Funciton: Ferrichrome-iron receptor
	RSP_3417	RSP_3417	Ferrichrome-iron receptor
Position: -119 Score: 4.3 Sequence: CTTGACAAAAACGCTCGGA Locus tag: RSP_0443 Name: iscR Funciton: Iron-sulfur cluster regulator IscR, Rrf2 family Locus tag: RSP_0442 Name: iscS Funciton: Cysteine desulfurase (EC 2.8.1.7) Locus tag: RSP_0440 Name: sufB Funciton: Iron-sulfur cluster assembly protein SufB Locus tag: RSP_0439 Name: RSP_0439 Funciton: protein of unknown function DUF74 Locus tag: RSP_0437 Name: sufC Funciton: Iron-sulfur cluster assembly ATPase protein SufC
	RSP_0443	iscR	Iron-sulfur cluster regulator IscR, Rrf2 family
	RSP_0442	iscS	Cysteine desulfurase (EC 2.8.1.7)
	RSP_0440	sufB	Iron-sulfur cluster assembly protein SufB
	RSP_0439	RSP_0439	protein of unknown function DUF74
	RSP_0437	sufC	Iron-sulfur cluster assembly ATPase protein SufC
Position: -142 Score: 4.6 Sequence: TCCGACTGTTCTTGTCGGA Locus tag: RSP_3416 Name: fecB Funciton: ABC-type Fe3+-hydroxamate transport system, periplasmic component Locus tag: RSP_3415 Name: fecC Funciton: ABC-type Fe3+-siderophore transport system, permease component Locus tag: RSP_3414 Name: fecD Funciton: ABC-type Fe3+-siderophore transport system, permease component Locus tag: RSP_3413 Name: fecE Funciton: ABC Fe+3-siderophore transporter, ATPase subunit
	RSP_3416	fecB	ABC-type Fe3+-hydroxamate transport system, periplasmic component
	RSP_3415	fecC	ABC-type Fe3+-siderophore transport system, permease component
	RSP_3414	fecD	ABC-type Fe3+-siderophore transport system, permease component
	RSP_3413	fecE	ABC Fe+3-siderophore transporter, ATPase subunit
Position: -56 Score: 4.4 Sequence: TCCGATTGAAAGACTCGGG Locus tag: RSP_1545 Name: COG3488 Funciton: Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites Locus tag: RSP_1544 Name: COG3489 Funciton: Predicted periplasmic lipoprotein Locus tag: RSP_1543 Name: COG3490 Funciton: Uncharacterised conserved protein UCP028101
	RSP_1545	COG3488	Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites
	RSP_1544	COG3489	Predicted periplasmic lipoprotein
	RSP_1543	COG3490	Uncharacterised conserved protein UCP028101
Position: -228 Score: 3.9 Sequence: ACCGACCGAAAGAATCAGC Position: -200 Score: 4.7 Sequence: TCCGACTGATTCAGTCACC Locus tag: RSP_6006 Name: hemP Funciton: Hemin uptake protein HemP Locus tag: RSP_1548 Name: irpA Funciton: Iron-regulated protein A precursor Locus tag: RSP_1547 Name: bfd Funciton: Bacterioferritin-associated ferredoxin Locus tag: RSP_1546 Name: bfr Funciton: Bacterioferritin (cytochrome b1)
	RSP_6006	hemP	Hemin uptake protein HemP
	RSP_1548	irpA	Iron-regulated protein A precursor
	RSP_1547	bfd	Bacterioferritin-associated ferredoxin
	RSP_1546	bfr	Bacterioferritin (cytochrome b1)

Export
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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of IscR in Rhodobacter sphaeroides 2.4.1

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --