Regulon of MetR in Citrobacter koseri ATCC BAA-895

Properties
Regulator type:	Transcription factor
TF locus tag:	CKO_04215
Regulator family:	LysR
Regulation mode:	repressor (activator)
Biological process:	Methionine biosynthesis
Effector:	Homocysteine
Regulog:	MetR - Enterobacteriales
Statistics of regulated genes:
- Genes	11
- Operons	10
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 140 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By trascription factor - MetR
By TF family - LysR
By effector - Homocysteine
By pathway - Methionine biosynthesis

Regulated operons
	Locus Tag	Name	Function
Position: -13 Score: 4.9 Sequence: GTGAAGGACTTTCAT Locus tag: CKO_00170 Name: metR Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
	CKO_00170	metR	Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
Position: -209 Score: 4.6 Sequence: GTGAAAAATCTGCAT Locus tag: CKO_00237 Name: glyA Funciton: Serine hydroxymethyltransferase (EC 2.1.2.1)
	CKO_00237	glyA	Serine hydroxymethyltransferase (EC 2.1.2.1)
Position: -180 Score: 4.1 Sequence: ATGAAAAAGCGTCAC Position: -149 Score: 4.2 Sequence: GTGAATTTATTTCAA Position: -129 Score: 3.6 Sequence: ATGAATTTTTCTCGG Locus tag: CKO_01563 Name: metE2 Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
	CKO_01563	metE2	Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
Position: -81 Score: 4.1 Sequence: ATGCGCGTCTTTCAC Locus tag: CKO_04036 Name: luxS Funciton: S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS
	CKO_04036	luxS	S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS
Position: -50 Score: 4.3 Sequence: CTGAACATGTCTCAT Locus tag: CKO_03902 Name: metH Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
	CKO_03902	metH	5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
Position: -125 Score: 4.6 Sequence: ATGCAGATTTTTCAC Locus tag: CKO_00235 Name: hmp Funciton: Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)
	CKO_00235	hmp	Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)
Position: -250 Score: 4.9 Sequence: ATGAAAGTCCTTCAC Locus tag: CKO_00171 Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
	CKO_00171	metE	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Position: -111 Score: 4.8 Sequence: GTGAAACTTTCTCAC Locus tag: CKO_03907 Name: metA Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
	CKO_03907	metA	Homoserine O-succinyltransferase (EC 2.3.1.46)
Position: -156 Score: 4.4 Sequence: TTGAATTTTTTTCAC Position: -136 Score: 4.2 Sequence: CTGAGTATTCCTCAC Position: 0 Score: 4.6 Sequence: ATGAGCTTTTTTCAC Locus tag: CKO_03051 Name: metF Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
	CKO_03051	metF	5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Position: -182 Score: 4.2 Sequence: ATGAATATGACTCAT Locus tag: CKO_02940 Name: PF08908 Funciton: Protein of unknown function DUF1852 Locus tag: CKO_02941 Name: metE2-2 Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
	CKO_02940	PF08908	Protein of unknown function DUF1852
	CKO_02941	metE2-2	Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of MetR in Citrobacter koseri ATCC BAA-895

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --