Regulon of MetR in Enterobacter sp. 638

Properties
Regulator type:	Transcription factor
TF locus tag:	Ent638_3968
Regulator family:	LysR
Regulation mode:	repressor (activator)
Biological process:	Methionine biosynthesis
Effector:	Homocysteine
Regulog:	MetR - Enterobacteriales
Statistics of regulated genes:
- Genes	11
- Operons	10
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 140 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By trascription factor - MetR
By TF family - LysR
By effector - Homocysteine
By pathway - Methionine biosynthesis

Regulated operons
	Locus Tag	Name	Function
Position: -13 Score: 4.9 Sequence: GTGAAGGACTTTCAT Locus tag: Ent638_3968 Name: metR Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
	Ent638_3968	metR	Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
Position: -214 Score: 4.6 Sequence: ATGAAAAATGTGCAT Locus tag: Ent638_3036 Name: glyA Funciton: Serine hydroxymethyltransferase (EC 2.1.2.1)
	Ent638_3036	glyA	Serine hydroxymethyltransferase (EC 2.1.2.1)
Position: -191 Score: 3.8 Sequence: ATGAACATTTTGCGT Position: -152 Score: 4.4 Sequence: ATGAATAAAATTCAT Position: -132 Score: 3.6 Sequence: ATGAATTTTTCTCGG Locus tag: Ent638_1987 Name: metE2 Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
	Ent638_1987	metE2	Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
Position: -83 Score: 4.2 Sequence: ATGCGCGTCTTTCAT Locus tag: Ent638_3167 Name: luxS Funciton: S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS
	Ent638_3167	luxS	S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS
Position: -103 Score: 4.6 Sequence: ATGCACATTTTTCAT Locus tag: Ent638_3037 Name: hmp Funciton: Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)
	Ent638_3037	hmp	Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)
Position: -105 Score: 4.5 Sequence: GTGAACATGTCTCAT Locus tag: Ent638_0222 Name: metH Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
	Ent638_0222	metH	5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
Position: -156 Score: 4.7 Sequence: ATGAACTTCTTTCAT Position: -136 Score: 4.3 Sequence: CTGAACATTCCTCAC Position: 0 Score: 4.6 Sequence: ATGAGCTTTTTTCAC Locus tag: Ent638_4033 Name: metF Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
	Ent638_4033	metF	5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Position: -111 Score: 4.8 Sequence: GTGAAACTTTCTCAC Locus tag: Ent638_0217 Name: metA Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
	Ent638_0217	metA	Homoserine O-succinyltransferase (EC 2.3.1.46)
Position: -249 Score: 4.9 Sequence: ATGAAAGTCCTTCAC Locus tag: Ent638_3967 Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
	Ent638_3967	metE	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Position: -186 Score: 4.6 Sequence: ATGAAGAAACCTCAT Locus tag: Ent638_2112 Name: PF08908 Funciton: Protein of unknown function DUF1852 Locus tag: Ent638_2113 Name: metE2-2 Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
	Ent638_2112	PF08908	Protein of unknown function DUF1852
	Ent638_2113	metE2-2	Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of MetR in Enterobacter sp. 638

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --