Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of MetR in Escherichia coli str. K-12 substr. MG1655

Properties
Regulator type: Transcription factor
TF locus tag: b3828
Regulator family: LysR
Regulation mode: repressor (activator)
Biological process: Methionine biosynthesis
Effector: Homocysteine
Regulog: MetR - Enterobacteriales
Statistics of regulated genes:
- Genes 8
- Operons 8
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 140 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -34
Score: 3.7
Sequence: GCGCAAATTATTCAT
Position: -13
Score: 4.9
Sequence: GTGAAGGACTTTCAT
Locus tag: b3828
Name: metR
Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
metR
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family

Position: -109
Score: 4.3
Sequence: TTGAACAAATCTCAT
Locus tag: b4019
Name: metH
Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
metH
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)

Position: -81
Score: 4.2
Sequence: ATGCGCGTCTTTCAT
Locus tag: b2687
Name: luxS
Funciton: S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS
luxS
S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS

Position: -125
Score: 4.8
Sequence: ATGCAAATTTTTCAC
Locus tag: b2552
Name: hmp
Funciton: Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)
hmp
Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)

Position: -238
Score: 4.9
Sequence: ATGAAAGTCCTTCAC
Locus tag: b3829
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

Position: -111
Score: 4.5
Sequence: TTGAAACTTTCTCAC
Locus tag: b4013
Name: metA
Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
metA
Homoserine O-succinyltransferase (EC 2.3.1.46)

Position: -295
Score: 3.7
Sequence: ATGAAATATATTGAA
Position: -156
Score: 4.7
Sequence: CTGAAGTTTTTTCAT
Position: 0
Score: 4.6
Sequence: ATGAGCTTTTTTCAC
Locus tag: b3941
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
metF
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)

Position: -217
Score: 4.8
Sequence: GTGAAAAATTTGCAT
Locus tag: b2551
Name: glyA
Funciton: Serine hydroxymethyltransferase (EC 2.1.2.1)
glyA
Serine hydroxymethyltransferase (EC 2.1.2.1)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD