Regulon of MetR in Klebsiella pneumoniae subsp. pneumoniae MGH 78578
| Regulator type: | Transcription factor |
| TF locus tag: | KPN_04324 |
| Regulator family: | LysR |
| Regulation mode: | repressor (activator) |
| Biological process: | Methionine biosynthesis |
| Effector: | Homocysteine |
| Regulog: | MetR - Enterobacteriales |
| Statistics of regulated genes: | |
| - Genes | 12 |
| - Operons | 11 |
| Visualization: | |
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Allows to visualize regulon content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Enterobacteriales
- By trascription factor - MetR
- By TF family - LysR
- By effector - Homocysteine
- By pathway - Methionine biosynthesis
| Locus Tag | Name | Function | |
|---|---|---|---|
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Position: -217
Score: 4 Sequence: AAGAAAAAATCTCAA
Position: -13
Score: 4.9 Sequence: GTGAAGGACTTTCAT
Locus tag: KPN_04324
Name: metR Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
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metR
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Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
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Position: -249
Score: 4.9 Sequence: ATGAAAGTCCTTCAC
Locus tag: KPN_04325
Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
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metE
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5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
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Position: -98
Score: 3.9 Sequence: ATGAAATCCTCTCAA
Locus tag: KPN_02168
Name: metQ2 Funciton: Methionine ABC transporter substrate-binding protein |
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metQ2
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Methionine ABC transporter substrate-binding protein
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Position: -216
Score: 4.7 Sequence: ATGAAGAATTTGCAT
Locus tag: KPN_02876
Name: glyA Funciton: Serine hydroxymethyltransferase (EC 2.1.2.1) |
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glyA
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Serine hydroxymethyltransferase (EC 2.1.2.1)
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Position: -152
Score: 5 Sequence: TTGAAAATTTTTCAT
Position: -132
Score: 4.2 Sequence: ATGAAATATTCTCGT
Locus tag: KPN_01615
Name: metE2 Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14) |
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metE2
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Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
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Position: -83
Score: 4.2 Sequence: ATGCGCGTCTTTCAT
Locus tag: KPN_03018
Name: luxS Funciton: S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS |
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luxS
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S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS
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Position: -124
Score: 4.7 Sequence: ATGCAAATTCTTCAT
Locus tag: KPN_02877
Name: hmp Funciton: Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17) |
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hmp
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Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)
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Position: -106
Score: 4.3 Sequence: CTGAACATGTCTCAT
Locus tag: KPN_04399
Name: metH Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) |
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metH
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5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
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Position: -155
Score: 4.8 Sequence: ATGAACTTTTTTCAT
Position: 0
Score: 4.6 Sequence: ATGAGCTTTTTTCAC
Locus tag: KPN_04239
Name: metF Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
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metF
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5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
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Position: -111
Score: 4.8 Sequence: GTGAAATTTTCTCAC
Locus tag: KPN_04394
Name: metA Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46) |
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metA
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Homoserine O-succinyltransferase (EC 2.3.1.46)
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Position: -192
Score: 4.2 Sequence: ATGAGGATGGCTCAT
Locus tag: KPN_02153
Name: PF08908 Funciton: Protein of unknown function DUF1852
Locus tag: KPN_02152
Name: metE2-2 Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14) |
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PF08908
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Protein of unknown function DUF1852
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metE2-2
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Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |