Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of MetR in Salmonella typhimurium LT2

Properties
Regulator type: Transcription factor
TF locus tag: STM3964
Regulator family: LysR
Regulation mode: repressor (activator)
Biological process: Methionine biosynthesis
Effector: Homocysteine
Regulog: MetR - Enterobacteriales
Statistics of regulated genes:
- Genes 8
- Operons 8
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 140 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -13
Score: 4.9
Sequence: GTGAAGGACTTTCAT
Locus tag: STM3964
Name: metR
Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
metR
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family

Position: -250
Score: 4.9
Sequence: ATGAAAGTCCTTCAC
Locus tag: STM3965
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

Position: -215
Score: 4.6
Sequence: GTGAAAAATCTGCAT
Locus tag: STM2555
Name: glyA
Funciton: Serine hydroxymethyltransferase (EC 2.1.2.1)
glyA
Serine hydroxymethyltransferase (EC 2.1.2.1)

Position: -80
Score: 4.2
Sequence: ATGCGCGTCTTTCAT
Locus tag: STM2817
Name: luxS
Funciton: S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS
luxS
S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS

Position: -124
Score: 4.6
Sequence: ATGCAGATTTTTCAC
Locus tag: STM2556
Name: hmp
Funciton: Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)
hmp
Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)

Position: -156
Score: 4.3
Sequence: ATGAAGAAAATTCAA
Position: -136
Score: 4.4
Sequence: CTGAATATTCCTCAT
Position: 0
Score: 4.6
Sequence: ATGAGCTTTTTTCAC
Locus tag: STM4105
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
metF
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)

Position: -111
Score: 4.8
Sequence: GTGAAACTTTCTCAC
Locus tag: STM4182
Name: metA
Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
metA
Homoserine O-succinyltransferase (EC 2.3.1.46)

Position: -93
Score: 4.3
Sequence: CTGAACATGTCTCAT
Locus tag: STM4188.S
Name: metH
Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
metH
5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
Export
Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD