Regulon of MetR in Serratia proteamaculans 568

Properties
Regulator type:	Transcription factor
TF locus tag:	Spro_0241
Regulator family:	LysR
Regulation mode:	repressor (activator)
Biological process:	Methionine biosynthesis
Effector:	Homocysteine
Regulog:	MetR - Enterobacteriales
Statistics of regulated genes:
- Genes	11
- Operons	10
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 140 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By trascription factor - MetR
By TF family - LysR
By effector - Homocysteine
By pathway - Methionine biosynthesis

Regulated operons
	Locus Tag	Name	Function
Position: -161 Score: 4.2 Sequence: GTGAAATTCTTTCTC Position: -139 Score: 3.8 Sequence: GTGAGGATTAATCAT Position: 0 Score: 4.6 Sequence: ATGAGTTTTTTTCAC Locus tag: Spro_4784 Name: metF Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
	Spro_4784	metF	5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Position: -174 Score: 4.2 Sequence: CTGAGCTTTTTTCAG Position: -13 Score: 4.7 Sequence: GTGAAGGACTCTCAT Locus tag: Spro_0241 Name: metR Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
	Spro_0241	metR	Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
Position: -101 Score: 4.1 Sequence: ATGCGCGTCTTTCAC Locus tag: Spro_0848 Name: luxS Funciton: S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS
	Spro_0848	luxS	S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS
Position: -166 Score: 4.5 Sequence: CTGAAAAACTCTCAA Locus tag: Spro_4490 Name: metH Funciton: 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
	Spro_4490	metH	5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13)
Position: -169 Score: 4.4 Sequence: ATGCGGTTTTTTCAT Locus tag: Spro_3639 Name: hmp Funciton: Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)
	Spro_3639	hmp	Flavohemoprotein (Hemoglobin-like protein) (Flavohemoglobin) (Nitric oxide dioxygenase) (EC 1.14.12.17)
Position: -218 Score: 4.4 Sequence: ATGAAAAAACCGCAT Locus tag: Spro_3638 Name: glyA Funciton: Serine hydroxymethyltransferase (EC 2.1.2.1)
	Spro_3638	glyA	Serine hydroxymethyltransferase (EC 2.1.2.1)
Position: -108 Score: 5 Sequence: ATGAAACATTTTCAC Locus tag: Spro_4504 Name: metA Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
	Spro_4504	metA	Homoserine O-succinyltransferase (EC 2.3.1.46)
Position: -107 Score: 4.7 Sequence: ATGAGAGTCCTTCAC Locus tag: Spro_0242 Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
	Spro_0242	metE	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Position: -177 Score: 4.5 Sequence: ATGAATTTCTCTCAC Position: -157 Score: 4.1 Sequence: ATGAAAATTCTTCTA Locus tag: Spro_1044 Name: metE2 Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
	Spro_1044	metE2	Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
Position: -183 Score: 4.4 Sequence: ATGAATATGCCTCAT Locus tag: Spro_3175 Name: PF08908 Funciton: Protein of unknown function DUF1852 Locus tag: Spro_3176 Name: metE2-2 Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
	Spro_3175	PF08908	Protein of unknown function DUF1852
	Spro_3176	metE2-2	Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of MetR in Serratia proteamaculans 568

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --