Statistics of regulated genes

Genome	Genes	Operons
Pyrococcus abyssi GE5	9	4
Pyrococcus furiosus DSM 3638	9	4
Pyrococcus horikoshii OT3	6	3
Thermococcus gammatolerans EJ3	4	3
Thermococcus kodakaraensis KOD1	5	3
Thermococcus onnurineus NA1	5	2
Thermococcus sibiricus MM 739	10	3

Clusters of co-Regulated Orthologous operoNs (CRONs)

Genes								Function
CRON 1.
cytX	Pyrococcus abyssi GE5 Gene: PAB1643: Hydroxymethylpyrimidine transporter CytX	Pyrococcus furiosus DSM 3638 Gene: PF1336: Hydroxymethylpyrimidine transporter CytX	Pyrococcus horikoshii OT3 Gene: PH1159: Hydroxymethylpyrimidine transporter CytX	Thermococcus gammatolerans EJ3	Thermococcus kodakaraensis KOD1	Thermococcus onnurineus NA1	* Thermococcus sibiricus MM 739 Site: position = -70 score = 5.05112 sequence = ATAACTTGGTTTT Gene: TSIB_0467: Hydroxymethylpyrimidine transporter CytX	Hydroxymethylpyrimidine transporter CytX
tenA1	* Pyrococcus abyssi GE5 Site: position = -70 score = 5.05112 sequence = ATAACCAAGTTTT Gene: PAB1641: Thiaminase II (EC 3.5.99.2)	* Pyrococcus furiosus DSM 3638 Site: position = -68 score = 5.05112 sequence = ATAACTTGGTTTT Gene: PF1338: Thiaminase II (EC 3.5.99.2)	* Pyrococcus horikoshii OT3 Site: position = -214 score = 4.60795 sequence = AAACCTCAGTTTT Site: position = -61 score = 4.67474 sequence = ATAACAAGGTTAT Gene: PH1161: Thiaminase II (EC 3.5.99.2)	Thermococcus gammatolerans EJ3	Thermococcus kodakaraensis KOD1	Thermococcus onnurineus NA1	Thermococcus sibiricus MM 739 Gene: TSIB_0466: Thiaminase II (EC 3.5.99.2)	Thiaminase II (EC 3.5.99.2)
thiM	Pyrococcus abyssi GE5 Gene: PAB2432: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Pyrococcus furiosus DSM 3638 Gene: PF1335: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Pyrococcus horikoshii OT3 Gene: PH1157: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Thermococcus gammatolerans EJ3	Thermococcus kodakaraensis KOD1	Thermococcus onnurineus NA1	Thermococcus sibiricus MM 739 Gene: TSIB_0465: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Hydroxyethylthiazole kinase (EC 2.7.1.50)
thiE	Pyrococcus abyssi GE5 Gene: PAB1645: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Pyrococcus furiosus DSM 3638 Gene: PF1334: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Pyrococcus horikoshii OT3 Gene: PH1156: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Thermococcus gammatolerans EJ3	Thermococcus kodakaraensis KOD1	Thermococcus onnurineus NA1	Thermococcus sibiricus MM 739 Gene: TSIB_0464: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
thiW	Pyrococcus abyssi GE5	Pyrococcus furiosus DSM 3638	Pyrococcus horikoshii OT3	Thermococcus gammatolerans EJ3	Thermococcus kodakaraensis KOD1	Thermococcus onnurineus NA1	Thermococcus sibiricus MM 739 Gene: TSIB_0463: Thiazole transporter ThiW	Thiazole transporter ThiW
thiDN	Pyrococcus abyssi GE5 Gene: PAB1646: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)	Pyrococcus furiosus DSM 3638 Gene: PF1333: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)	Pyrococcus horikoshii OT3 Gene: PH1155: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)	Thermococcus gammatolerans EJ3 Gene: TGAM_1271: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)	Thermococcus kodakaraensis KOD1 Gene: TK0435: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)	Thermococcus onnurineus NA1	Thermococcus sibiricus MM 739 Gene: TSIB_0462: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)	Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)
tenA2	Pyrococcus abyssi GE5 Gene: PAB1642: Thiaminase II (EC 3.5.99.2)	Pyrococcus furiosus DSM 3638 Gene: PF1337: Thiaminase II (EC 3.5.99.2)	Pyrococcus horikoshii OT3 Gene: PH1160: Thiaminase II (EC 3.5.99.2)	Thermococcus gammatolerans EJ3	Thermococcus kodakaraensis KOD1	Thermococcus onnurineus NA1	Thermococcus sibiricus MM 739	Thiaminase II (EC 3.5.99.2)
thi4	* Pyrococcus abyssi GE5 Site: position = -47 score = 5.1769 sequence = ATAACAAAGTTTT Site: position = -26 score = 5.55328 sequence = AAAACTAAGTTTT Gene: PAB0536: Thiazole biosynthetic enzyme Thi4	* Pyrococcus furiosus DSM 3638 Site: position = -93 score = 5.22862 sequence = AAAACTTGGTTTT Site: position = -48 score = 5.3544 sequence = AAAACAAAGTTTT Site: position = -27 score = 5.36989 sequence = AAAACTCAGTTTT Gene: PF1530: Thiazole biosynthetic enzyme Thi4	* Pyrococcus horikoshii OT3 Site: position = -18 score = 4.51375 sequence = AAAATGAAGTTTT Site: position = -39 score = 5.1769 sequence = ATAACAAAGTTTT Gene: PH1357: Thiazole biosynthetic enzyme Thi4	* Thermococcus gammatolerans EJ3 Site: position = -45 score = 5.55328 sequence = AAAACTTAGTTTT Site: position = -66 score = 5.1769 sequence = ATAACAAAGTTTT Gene: TGAM_1270: Thiazole biosynthetic enzyme Thi4	* Thermococcus kodakaraensis KOD1 Site: position = -45 score = 5.55328 sequence = AAAACTTAGTTTT Site: position = -66 score = 5.1769 sequence = ATAACAAAGTTTT Gene: TK0434: Thiazole biosynthetic enzyme Thi4	Thermococcus onnurineus NA1	Thermococcus sibiricus MM 739	Thiazole biosynthetic enzyme Thi4
CRON 2.
thiC	* Pyrococcus abyssi GE5 Site: position = -38 score = 4.39625 sequence = ATTACTTGGTTTT Gene: PAB1930: Thiamin biosynthesis protein ThiC	* Pyrococcus furiosus DSM 3638 Site: position = -114 score = 5.36989 sequence = AAAACTGAGTTTT Site: position = -93 score = 5.3544 sequence = AAAACTTTGTTTT Site: position = -48 score = 5.22862 sequence = AAAACCAAGTTTT Gene: PF1531: Thiamin biosynthesis protein ThiC	Pyrococcus horikoshii OT3	* Thermococcus gammatolerans EJ3 Site: position = -41 score = 5.1769 sequence = AAAACTTTGTTAT Site: position = -62 score = 5.55328 sequence = AAAACTAAGTTTT Gene: TGAM_1269: Thiamin biosynthesis protein ThiC	* Thermococcus kodakaraensis KOD1 Site: position = -63 score = 5.55328 sequence = AAAACTAAGTTTT Site: position = -42 score = 5.1769 sequence = AAAACTTTGTTAT Gene: TK0433: Thiamin biosynthesis protein ThiC	Thermococcus onnurineus NA1	Thermococcus sibiricus MM 739	Thiamin biosynthesis protein ThiC
CRON 3.
thiB	* Pyrococcus abyssi GE5 Site: position = -37 score = 4.11726 sequence = AAAATCTTATTTT Gene: PAB1835: Thiamin ABC transporter, substrate-binding component	*2 Pyrococcus furiosus DSM 3638 Gene: PF1518: Thiamin ABC transporter, substrate-binding component Site: position = -45 score = 4.64749 sequence = AGAACACAGTTTT Gene: PF1751: Thiamin ABC transporter, substrate-binding component	* Pyrococcus horikoshii OT3 Site: position = -42 score = 4.28918 sequence = ATAGCTTGGTTTT Site: position = -63 score = 4.89841 sequence = AATACTTAGTTTT Gene: PH1349: Thiamin ABC transporter, substrate-binding component	* Thermococcus gammatolerans EJ3 Site: position = -16 score = 4.46194 sequence = AAAACCGCGTTTT Gene: TGAM_1706: Thiamin ABC transporter, substrate-binding component	Thermococcus kodakaraensis KOD1 Gene: TK0757: Thiamin ABC transporter, substrate-binding component	Thermococcus onnurineus NA1 Gene: TON_0963: Thiamin ABC transporter, substrate-binding component	* Thermococcus sibiricus MM 739 Site: position = -15 score = 4.91069 sequence = AAAAATTAGTTTT Site: position = -36 score = 4.46998 sequence = AGAACAGAGTTAT Gene: TSIB_0369: Thiamin ABC transporter, substrate-binding component	Thiamin ABC transporter, substrate-binding component
CRON 4.
thiP	Pyrococcus abyssi GE5 Gene: PAB0543: Thiamin ABC transporter, transmembrane component	3 Pyrococcus furiosus DSM 3638 Gene: PF1749: Thiamin ABC transporter, transmembrane component Gene: PF1748: Thiamin ABC transporter, transmembrane component Gene: PF1520: Thiamin ABC transporter, transmembrane component	Pyrococcus horikoshii OT3 Gene: PH1352: Thiamin ABC transporter, transmembrane component	Thermococcus gammatolerans EJ3 Gene: TGAM_1704: Thiamin ABC transporter, transmembrane component	Thermococcus kodakaraensis KOD1 Gene: TK0159: Thiamin ABC transporter, transmembrane component	* Thermococcus onnurineus NA1 Site: position = -17 score = 4.5217 sequence = AAAACCGAGTTGT Gene: TON_1959: Thiamin ABC transporter, transmembrane component	Thermococcus sibiricus MM 739 Gene: TSIB_0367: Thiamin ABC transporter, transmembrane component	Thiamin ABC transporter, transmembrane component
thiQ	Pyrococcus abyssi GE5 Gene: PAB0545: Thiamin ABC transporter, ATPase component	2 Pyrococcus furiosus DSM 3638 Gene: PF1750: Thiamin ABC transporter, ATPase component Gene: PF1519: Thiamin ABC transporter, ATPase component	Pyrococcus horikoshii OT3 Gene: PH1350: Thiamin ABC transporter, ATPase component	Thermococcus gammatolerans EJ3 Gene: TGAM_1705: Thiamin ABC transporter, ATPase component	Thermococcus kodakaraensis KOD1 Gene: TK0158: Thiamin ABC transporter, ATPase component	Thermococcus onnurineus NA1 Gene: TON_1958: Thiamin ABC transporter, ATPase component	Thermococcus sibiricus MM 739 Gene: TSIB_0368: Thiamin ABC transporter, ATPase component	Thiamin ABC transporter, ATPase component
CRON 5.
thiR	Pyrococcus abyssi GE5 Gene: PAB0877: Thiamin-phosphate synthase-like transcriptional regulator ThiR	Pyrococcus furiosus DSM 3638 Gene: PF0601: Thiamin-phosphate synthase-like transcriptional regulator ThiR	Pyrococcus horikoshii OT3 Gene: PH0716: Thiamin-phosphate synthase-like transcriptional regulator ThiR	Thermococcus gammatolerans EJ3 Gene: TGAM_2087: Thiamin-phosphate synthase-like transcriptional regulator ThiR	* Thermococcus kodakaraensis KOD1 Site: position = -25 score = 4.20293 sequence = ATAACCTGGTTGT Gene: TK2197: Thiamin-phosphate synthase-like transcriptional regulator ThiR	* Thermococcus onnurineus NA1 Site: position = -24 score = 4.54306 sequence = ATAACCGGGTTTT Gene: TON_1436: Thiamin-phosphate synthase-like transcriptional regulator ThiR	* Thermococcus sibiricus MM 739 Site: position = -37 score = 5.19239 sequence = ATAACTGAGTTTT Gene: TSIB_0198: Thiamin-phosphate synthase-like transcriptional regulator ThiR	Thiamin-phosphate synthase-like transcriptional regulator ThiR
TON_1435	Pyrococcus abyssi GE5	Pyrococcus furiosus DSM 3638	Pyrococcus horikoshii OT3	Thermococcus gammatolerans EJ3	Thermococcus kodakaraensis KOD1	Thermococcus onnurineus NA1 Gene: TON_1435: hypothetical protein	Thermococcus sibiricus MM 739	hypothetical protein
yjbQ	Pyrococcus abyssi GE5 Gene: PAB0878: YjbQ (alternate ThiE)	Pyrococcus furiosus DSM 3638 Gene: PF0680: YjbQ (alternate ThiE)	Pyrococcus horikoshii OT3 Gene: PH0713: YjbQ (alternate ThiE)	Thermococcus gammatolerans EJ3 Gene: TGAM_2086: YjbQ (alternate ThiE)	Thermococcus kodakaraensis KOD1 Gene: TK2198: YjbQ (alternate ThiE)	Thermococcus onnurineus NA1 Gene: TON_1434: YjbQ (alternate ThiE)	Thermococcus sibiricus MM 739 Gene: TSIB_0200: YjbQ (alternate ThiE)	YjbQ (alternate ThiE)
TSIB_0199	Pyrococcus abyssi GE5	Pyrococcus furiosus DSM 3638	Pyrococcus horikoshii OT3	Thermococcus gammatolerans EJ3	Thermococcus kodakaraensis KOD1	Thermococcus onnurineus NA1	Thermococcus sibiricus MM 739 Gene: TSIB_0199: hypothetical protein	hypothetical protein

Export

	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD