Regulog ThiR - Thermococcales
| Regulator type: | Transcription factor |
| Regulator family: | [Other] |
| Regulation mode: | repressor |
| Biological process: | Thiamine transport; Thiamine biosynthesis |
| Effector: | Thiamine phosphate |
| Phylum: | Euryarchaeota |
| Visualization: | |
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Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By trascription factor - ThiR
- By taxonomy - Thermococcales
- By TF family - [Other]
- By effector - Thiamine phosphate
- By pathway - Thiamine transport
- By pathway - Thiamine biosynthesis
| Genome | Genes | Operons |
|---|---|---|
| Pyrococcus abyssi GE5 | 9 | 4 |
| Pyrococcus furiosus DSM 3638 | 9 | 4 |
| Pyrococcus horikoshii OT3 | 6 | 3 |
| Thermococcus gammatolerans EJ3 | 4 | 3 |
| Thermococcus kodakaraensis KOD1 | 5 | 3 |
| Thermococcus onnurineus NA1 | 5 | 2 |
| Thermococcus sibiricus MM 739 | 10 | 3 |
| Genes | Function | |||||||
|---|---|---|---|---|---|---|---|---|
| CRON 1. | ||||||||
| cytX |
Gene: PAB1643: Hydroxymethylpyrimidine transporter CytX |
Gene: PF1336: Hydroxymethylpyrimidine transporter CytX |
Gene: PH1159: Hydroxymethylpyrimidine transporter CytX |
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*
Thermococcus sibiricus MM 739 Site: position = -70 score = 5.05112 sequence = ATAACTTGGTTTT Gene: TSIB_0467: Hydroxymethylpyrimidine transporter CytX |
Hydroxymethylpyrimidine transporter CytX |
| tenA1 |
*
Pyrococcus abyssi GE5 Site: position = -70 score = 5.05112 sequence = ATAACCAAGTTTT Gene: PAB1641: Thiaminase II (EC 3.5.99.2) |
*
Pyrococcus furiosus DSM 3638 Site: position = -68 score = 5.05112 sequence = ATAACTTGGTTTT Gene: PF1338: Thiaminase II (EC 3.5.99.2) |
*
Pyrococcus horikoshii OT3 Site: position = -214 score = 4.60795 sequence = AAACCTCAGTTTT Site: position = -61 score = 4.67474 sequence = ATAACAAGGTTAT Gene: PH1161: Thiaminase II (EC 3.5.99.2) |
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Gene: TSIB_0466: Thiaminase II (EC 3.5.99.2) |
Thiaminase II (EC 3.5.99.2) |
| thiM |
Gene: PAB2432: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
Gene: PF1335: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
Gene: PH1157: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
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Gene: TSIB_0465: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
Hydroxyethylthiazole kinase (EC 2.7.1.50) |
| thiE |
Gene: PAB1645: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: PF1334: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Gene: PH1156: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
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Gene: TSIB_0464: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
| thiW |
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Gene: TSIB_0463: Thiazole transporter ThiW |
Thiazole transporter ThiW |
| thiDN |
Gene: PAB1646: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3) |
Gene: PF1333: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3) |
Gene: PH1155: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3) |
Gene: TGAM_1271: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3) |
Gene: TK0435: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3) |
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Gene: TSIB_0462: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3) |
Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3) |
| tenA2 |
Gene: PAB1642: Thiaminase II (EC 3.5.99.2) |
Gene: PF1337: Thiaminase II (EC 3.5.99.2) |
Gene: PH1160: Thiaminase II (EC 3.5.99.2) |
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Thiaminase II (EC 3.5.99.2) |
| thi4 |
*
Pyrococcus abyssi GE5 Site: position = -47 score = 5.1769 sequence = ATAACAAAGTTTT Site: position = -26 score = 5.55328 sequence = AAAACTAAGTTTT Gene: PAB0536: Thiazole biosynthetic enzyme Thi4 |
*
Pyrococcus furiosus DSM 3638 Site: position = -93 score = 5.22862 sequence = AAAACTTGGTTTT Site: position = -48 score = 5.3544 sequence = AAAACAAAGTTTT Site: position = -27 score = 5.36989 sequence = AAAACTCAGTTTT Gene: PF1530: Thiazole biosynthetic enzyme Thi4 |
*
Pyrococcus horikoshii OT3 Site: position = -18 score = 4.51375 sequence = AAAATGAAGTTTT Site: position = -39 score = 5.1769 sequence = ATAACAAAGTTTT Gene: PH1357: Thiazole biosynthetic enzyme Thi4 |
*
Thermococcus gammatolerans EJ3 Site: position = -45 score = 5.55328 sequence = AAAACTTAGTTTT Site: position = -66 score = 5.1769 sequence = ATAACAAAGTTTT Gene: TGAM_1270: Thiazole biosynthetic enzyme Thi4 |
*
Thermococcus kodakaraensis KOD1 Site: position = -45 score = 5.55328 sequence = AAAACTTAGTTTT Site: position = -66 score = 5.1769 sequence = ATAACAAAGTTTT Gene: TK0434: Thiazole biosynthetic enzyme Thi4 |
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Thiazole biosynthetic enzyme Thi4 |
| CRON 2. | ||||||||
| thiC |
*
Pyrococcus abyssi GE5 Site: position = -38 score = 4.39625 sequence = ATTACTTGGTTTT Gene: PAB1930: Thiamin biosynthesis protein ThiC |
*
Pyrococcus furiosus DSM 3638 Site: position = -114 score = 5.36989 sequence = AAAACTGAGTTTT Site: position = -93 score = 5.3544 sequence = AAAACTTTGTTTT Site: position = -48 score = 5.22862 sequence = AAAACCAAGTTTT Gene: PF1531: Thiamin biosynthesis protein ThiC |
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*
Thermococcus gammatolerans EJ3 Site: position = -41 score = 5.1769 sequence = AAAACTTTGTTAT Site: position = -62 score = 5.55328 sequence = AAAACTAAGTTTT Gene: TGAM_1269: Thiamin biosynthesis protein ThiC |
*
Thermococcus kodakaraensis KOD1 Site: position = -63 score = 5.55328 sequence = AAAACTAAGTTTT Site: position = -42 score = 5.1769 sequence = AAAACTTTGTTAT Gene: TK0433: Thiamin biosynthesis protein ThiC |
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Thiamin biosynthesis protein ThiC |
| CRON 3. | ||||||||
| thiB |
*
Pyrococcus abyssi GE5 Site: position = -37 score = 4.11726 sequence = AAAATCTTATTTT Gene: PAB1835: Thiamin ABC transporter, substrate-binding component |
*2
Pyrococcus furiosus DSM 3638 Gene: PF1518: Thiamin ABC transporter, substrate-binding component Site: position = -45 score = 4.64749 sequence = AGAACACAGTTTT Gene: PF1751: Thiamin ABC transporter, substrate-binding component |
*
Pyrococcus horikoshii OT3 Site: position = -42 score = 4.28918 sequence = ATAGCTTGGTTTT Site: position = -63 score = 4.89841 sequence = AATACTTAGTTTT Gene: PH1349: Thiamin ABC transporter, substrate-binding component |
*
Thermococcus gammatolerans EJ3 Site: position = -16 score = 4.46194 sequence = AAAACCGCGTTTT Gene: TGAM_1706: Thiamin ABC transporter, substrate-binding component |
Gene: TK0757: Thiamin ABC transporter, substrate-binding component |
Gene: TON_0963: Thiamin ABC transporter, substrate-binding component |
*
Thermococcus sibiricus MM 739 Site: position = -15 score = 4.91069 sequence = AAAAATTAGTTTT Site: position = -36 score = 4.46998 sequence = AGAACAGAGTTAT Gene: TSIB_0369: Thiamin ABC transporter, substrate-binding component |
Thiamin ABC transporter, substrate-binding component |
| CRON 4. | ||||||||
| thiP |
Gene: PAB0543: Thiamin ABC transporter, transmembrane component |
3
Pyrococcus furiosus DSM 3638 Gene: PF1749: Thiamin ABC transporter, transmembrane component Gene: PF1748: Thiamin ABC transporter, transmembrane component Gene: PF1520: Thiamin ABC transporter, transmembrane component |
Gene: PH1352: Thiamin ABC transporter, transmembrane component |
Gene: TGAM_1704: Thiamin ABC transporter, transmembrane component |
Gene: TK0159: Thiamin ABC transporter, transmembrane component |
*
Thermococcus onnurineus NA1 Site: position = -17 score = 4.5217 sequence = AAAACCGAGTTGT Gene: TON_1959: Thiamin ABC transporter, transmembrane component |
Gene: TSIB_0367: Thiamin ABC transporter, transmembrane component |
Thiamin ABC transporter, transmembrane component |
| thiQ |
Gene: PAB0545: Thiamin ABC transporter, ATPase component |
2
Pyrococcus furiosus DSM 3638 Gene: PF1750: Thiamin ABC transporter, ATPase component Gene: PF1519: Thiamin ABC transporter, ATPase component |
Gene: PH1350: Thiamin ABC transporter, ATPase component |
Gene: TGAM_1705: Thiamin ABC transporter, ATPase component |
Gene: TK0158: Thiamin ABC transporter, ATPase component |
Gene: TON_1958: Thiamin ABC transporter, ATPase component |
Gene: TSIB_0368: Thiamin ABC transporter, ATPase component |
Thiamin ABC transporter, ATPase component |
| CRON 5. | ||||||||
| thiR |
Gene: PAB0877: Thiamin-phosphate synthase-like transcriptional regulator ThiR |
Gene: PF0601: Thiamin-phosphate synthase-like transcriptional regulator ThiR |
Gene: PH0716: Thiamin-phosphate synthase-like transcriptional regulator ThiR |
Gene: TGAM_2087: Thiamin-phosphate synthase-like transcriptional regulator ThiR |
*
Thermococcus kodakaraensis KOD1 Site: position = -25 score = 4.20293 sequence = ATAACCTGGTTGT Gene: TK2197: Thiamin-phosphate synthase-like transcriptional regulator ThiR |
*
Thermococcus onnurineus NA1 Site: position = -24 score = 4.54306 sequence = ATAACCGGGTTTT Gene: TON_1436: Thiamin-phosphate synthase-like transcriptional regulator ThiR |
*
Thermococcus sibiricus MM 739 Site: position = -37 score = 5.19239 sequence = ATAACTGAGTTTT Gene: TSIB_0198: Thiamin-phosphate synthase-like transcriptional regulator ThiR |
Thiamin-phosphate synthase-like transcriptional regulator ThiR |
| TON_1435 |
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Gene: TON_1435: hypothetical protein |
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hypothetical protein |
| yjbQ |
Gene: PAB0878: YjbQ (alternate ThiE) |
Gene: PF0680: YjbQ (alternate ThiE) |
Gene: PH0713: YjbQ (alternate ThiE) |
Gene: TGAM_2086: YjbQ (alternate ThiE) |
Gene: TK2198: YjbQ (alternate ThiE) |
Gene: TON_1434: YjbQ (alternate ThiE) |
Gene: TSIB_0200: YjbQ (alternate ThiE) |
YjbQ (alternate ThiE) |
| TSIB_0199 |
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Gene: TSIB_0199: hypothetical protein |
hypothetical protein |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |