Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing thiM gene

Properties
Regulog: ThiR - Thermococcales
Regulator type: Transcription factor
Regulator family: [Other]
Regulation mode: repressor
Biological process: Thiamine transport; Thiamine biosynthesis
Effector: Thiamine phosphate
Phylum: Euryarchaeota
Built upon 35 sites [see more]
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Pyrococcus abyssi GE5
Position: -70
Score: 5.05112
Sequence: ATAACCAAGTTTT
Locus tag: PAB1641
Name: tenA1
Funciton: Thiaminase II (EC 3.5.99.2)
Locus tag: PAB1642
Name: tenA2
Funciton: Thiaminase II (EC 3.5.99.2)
Locus tag: PAB1643
Name: cytX
Funciton: Hydroxymethylpyrimidine transporter CytX
Locus tag: PAB2432
Name: thiM
Funciton: Hydroxyethylthiazole kinase (EC 2.7.1.50)
Locus tag: PAB1645
Name: thiE
Funciton: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
Locus tag: PAB1646
Name: thiDN
Funciton: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)
tenA1-tenA2-cytX-thiM-thiE-thiDN -70 5.1 ATAACCAAGTTTT PAB1641
Pyrococcus furiosus DSM 3638
Position: -68
Score: 5.05112
Sequence: ATAACTTGGTTTT
Locus tag: PF1338
Name: tenA1
Funciton: Thiaminase II (EC 3.5.99.2)
Locus tag: PF1337
Name: tenA2
Funciton: Thiaminase II (EC 3.5.99.2)
Locus tag: PF1336
Name: cytX
Funciton: Hydroxymethylpyrimidine transporter CytX
Locus tag: PF1335
Name: thiM
Funciton: Hydroxyethylthiazole kinase (EC 2.7.1.50)
Locus tag: PF1334
Name: thiE
Funciton: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
Locus tag: PF1333
Name: thiDN
Funciton: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)
tenA1-tenA2-cytX-thiM-thiE-thiDN -68 5.1 ATAACTTGGTTTT PF1338
Pyrococcus horikoshii OT3
Position: -214
Score: 4.60795
Sequence: AAACCTCAGTTTT
Position: -61
Score: 4.67474
Sequence: ATAACAAGGTTAT
Locus tag: PH1161
Name: tenA1
Funciton: Thiaminase II (EC 3.5.99.2)
Locus tag: PH1160
Name: tenA2
Funciton: Thiaminase II (EC 3.5.99.2)
Locus tag: PH1159
Name: cytX
Funciton: Hydroxymethylpyrimidine transporter CytX
Locus tag: PH1157
Name: thiM
Funciton: Hydroxyethylthiazole kinase (EC 2.7.1.50)
tenA1-tenA2-cytX-thiM -214 4.6 AAACCTCAGTTTT PH1161
-61 4.7 ATAACAAGGTTAT
Thermococcus sibiricus MM 739
Position: -70
Score: 5.05112
Sequence: ATAACTTGGTTTT
Locus tag: TSIB_0467
Name: cytX
Funciton: Hydroxymethylpyrimidine transporter CytX
Locus tag: TSIB_0466
Name: tenA1
Funciton: Thiaminase II (EC 3.5.99.2)
Locus tag: TSIB_0465
Name: thiM
Funciton: Hydroxyethylthiazole kinase (EC 2.7.1.50)
Locus tag: TSIB_0464
Name: thiE
Funciton: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
Locus tag: TSIB_0463
Name: thiW
Funciton: Thiazole transporter ThiW
Locus tag: TSIB_0462
Name: thiDN
Funciton: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)
cytX-tenA1-thiM-thiE-thiW-thiDN -70 5.1 ATAACTTGGTTTT TSIB_0467