Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of ThiR in Pyrococcus abyssi GE5

Properties
Regulator type: Transcription factor
TF locus tag: PAB0877
Regulator family: [Other]
Regulation mode: repressor
Biological process: Thiamine transport; Thiamine biosynthesis
Effector: Thiamine phosphate
Regulog: ThiR - Thermococcales
Statistics of regulated genes:
- Genes 9
- Operons 4
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 35 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -37
Score: 4.1
Sequence: AAAATCTTATTTT
Locus tag: PAB1835
Name: thiB
Funciton: Thiamin ABC transporter, substrate-binding component
thiB
Thiamin ABC transporter, substrate-binding component

Position: -70
Score: 5.1
Sequence: ATAACCAAGTTTT
Locus tag: PAB1641
Name: tenA1
Funciton: Thiaminase II (EC 3.5.99.2)
Locus tag: PAB1642
Name: tenA2
Funciton: Thiaminase II (EC 3.5.99.2)
Locus tag: PAB1643
Name: cytX
Funciton: Hydroxymethylpyrimidine transporter CytX
Locus tag: PAB2432
Name: thiM
Funciton: Hydroxyethylthiazole kinase (EC 2.7.1.50)
Locus tag: PAB1645
Name: thiE
Funciton: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
Locus tag: PAB1646
Name: thiDN
Funciton: Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)
tenA1
Thiaminase II (EC 3.5.99.2)
tenA2
Thiaminase II (EC 3.5.99.2)
cytX
Hydroxymethylpyrimidine transporter CytX
thiM
Hydroxyethylthiazole kinase (EC 2.7.1.50)
thiE
Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
thiDN
Phosphomethylpyrimidine kinase (EC 2.7.4.7) / Thiamin-phosphate synthase ThiN (EC 2.5.1.3)

Position: -38
Score: 4.4
Sequence: ATTACTTGGTTTT
Locus tag: PAB1930
Name: thiC
Funciton: Thiamin biosynthesis protein ThiC
thiC
Thiamin biosynthesis protein ThiC

Position: -47
Score: 5.2
Sequence: ATAACAAAGTTTT
Position: -26
Score: 5.6
Sequence: AAAACTAAGTTTT
Locus tag: PAB0536
Name: thi4
Funciton: Thiazole biosynthetic enzyme Thi4
thi4
Thiazole biosynthetic enzyme Thi4
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