Regulog UxuR - Clostridia-3

Properties
Regulator type:	Transcription factor
Regulator family:	LacI
Regulation mode:
Biological process:	Glucuronate utilization
Effector:
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 40 sites [see more]

Member of regulog collections

By taxonomy - Clostridia-3
By TF family - LacI
By pathway - Glucuronate utilization

Statistics of regulated genes
Genome	Genes	Operons
Bacteroides pectinophilus ATCC 43243	4	2
Blautia hansenii DSM 20583
Bryantella formatexigens DSM 14469	3	2
Clostridiales bacterium 1_7_47_FAA	5	4
Clostridium bolteae ATCC BAA-613	5	4
Clostridium nexile DSM 1787
Clostridium scindens ATCC 35704
Dorea formicigenerans ATCC 27755	4	2
Dorea longicatena DSM 13814
Eubacterium eligens ATCC 27750	4	2
Eubacterium rectale ATCC 33656
Roseburia intestinalis L1-82	5	4
Ruminococcus gnavus ATCC 29149	5	4
Ruminococcus lactaris ATCC 29176

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes															Function

CRON 1.
uxuR	* Bacteroides pectinophilus ATCC 43243 Site: position = -38 score = 6.46053 sequence = AAATGTAAGCACTTACATTT Gene: BACPEC_00410: Predicted transcription regulator for glucuronate utilization, LacI family	Blautia hansenii DSM 20583	* Bryantella formatexigens DSM 14469 Site: position = -102 score = 6.31368 sequence = TTGTGTAAGCGCTTACATTT Site: position = -252 score = 5.94932 sequence = CCATGTAAGCGCTTACAATC Gene: BRYFOR_01977: Predicted transcription regulator for glucuronate utilization, LacI family	* Clostridiales bacterium 1_7_47_FAA Site: position = -137 score = 6.22459 sequence = TATTGTAAGTACTTACAATT Site: position = -34 score = 5.75182 sequence = GCTTGTAAGCGCTTACAGAA Gene: Cbac1_010100002147: Predicted transcription regulator for glucuronate utilization, LacI family	* Clostridium bolteae ATCC BAA-613 Site: position = -137 score = 6.27947 sequence = TTTTGTAAGTGCTTACAATT Site: position = -34 score = 5.75182 sequence = GCTTGTAAGCGCTTACAGAA Gene: CLOBOL_01979: Predicted transcription regulator for glucuronate utilization, LacI family	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755 Gene: DORFOR_02950: Predicted transcription regulator for glucuronate utilization, LacI family	Dorea longicatena DSM 13814	* Eubacterium eligens ATCC 27750 Site: position = -211 score = 5.70207 sequence = GCATGTAAGCGCTTTCATAA Site: position = -83 score = 6.51541 sequence = ATATGTAAGCGCTTACATTT Gene: EUBELI_00906: Predicted transcription regulator for glucuronate utilization, LacI family	Eubacterium rectale ATCC 33656	* Roseburia intestinalis L1-82 Site: position = -249 score = 6.0675 sequence = TTTTGTAAGCGTTTACAATT Site: position = -63 score = 5.2542 sequence = TAATGAAACTGCTTTCATTT Gene: ROSINTL182_03040: Predicted transcription regulator for glucuronate utilization, LacI family	* Ruminococcus gnavus ATCC 29149 Site: position = -255 score = 5.51205 sequence = CATTGTAACAGCTTACATTA Site: position = -57 score = 5.61823 sequence = TAGTGTTAGTACTTACATTT Gene: RUMGNA_00428: Predicted transcription regulator for glucuronate utilization, LacI family	Ruminococcus lactaris ATCC 29176	Predicted transcription regulator for glucuronate utilization, LacI family
uxaC	Bacteroides pectinophilus ATCC 43243 Gene: BACPEC_00411: Uronate isomerase (EC 5.3.1.12)	Blautia hansenii DSM 20583 Gene: BLAHAN_01971: Uronate isomerase (EC 5.3.1.12)	Bryantella formatexigens DSM 14469 Gene: BRYFOR_01976: Uronate isomerase (EC 5.3.1.12)	Clostridiales bacterium 1_7_47_FAA Gene: Cbac1_010100002152: Uronate isomerase (EC 5.3.1.12)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01980: Uronate isomerase (EC 5.3.1.12)	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	* Dorea formicigenerans ATCC 27755 Site: position = -57 score = 6.2102 sequence = AAATGTAAGCGTTTACAATA Site: position = -235 score = 6.0243 sequence = ACGTGTAAGCGCTTACACTA Gene: DORFOR_02949: Uronate isomerase (EC 5.3.1.12)	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750 Gene: EUBELI_00905: Uronate isomerase (EC 5.3.1.12)	Eubacterium rectale ATCC 33656	Roseburia intestinalis L1-82 Gene: ROSINTL182_03041: Uronate isomerase (EC 5.3.1.12)	* Ruminococcus gnavus ATCC 29149 Site: position = -197 score = 5.88068 sequence = AAATGTAAGTATTTACAATT Site: position = -57 score = 6.05398 sequence = AAATGTAAGGGCTTACAAAA Gene: RUMGNA_00432: Uronate isomerase (EC 5.3.1.12)	Ruminococcus lactaris ATCC 29176	Uronate isomerase (EC 5.3.1.12)

CRON 2.
uxaA	Bacteroides pectinophilus ATCC 43243 Gene: BACPEC_00406: Altronate hydrolase (EC 4.2.1.7)	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469 Gene: BRYFOR_03984: Altronate hydrolase (EC 4.2.1.7)	* Clostridiales bacterium 1_7_47_FAA Site: position = -63 score = 6.22459 sequence = AATTGTAAGTACTTACAATA Site: position = -166 score = 5.75182 sequence = TTCTGTAAGCGCTTACAAGC Gene: Cbac1_010100002142: Altronate hydrolase (EC 4.2.1.7)	2 Clostridium bolteae ATCC BAA-613* Gene: CLOBOL_05067: Altronate hydrolase (EC 4.2.1.7) Site: position = -89 score = 6.27947 sequence = AATTGTAAGCACTTACAAAA Site: position = -192 score = 5.75182 sequence = TTCTGTAAGCGCTTACAAGC Gene: CLOBOL_01978: Altronate hydrolase (EC 4.2.1.7)	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	* Dorea formicigenerans ATCC 27755 Site: position = -148 score = 6.0243 sequence = TAGTGTAAGCGCTTACACGT Gene: DORFOR_02948: Altronate hydrolase (EC 4.2.1.7)	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750 Gene: EUBELI_00908: Altronate hydrolase (EC 4.2.1.7)	Eubacterium rectale ATCC 33656	Roseburia intestinalis L1-82 Gene: ROSINTL182_03037: Altronate hydrolase (EC 4.2.1.7)	* Ruminococcus gnavus ATCC 29149 Site: position = -43 score = 5.88068 sequence = AATTGTAAATACTTACATTT Site: position = -183 score = 6.05398 sequence = TTTTGTAAGCCCTTACATTT Gene: RUMGNA_00433: Altronate hydrolase (EC 4.2.1.7)	Ruminococcus lactaris ATCC 29176	Altronate hydrolase (EC 4.2.1.7)
uxaB	* Bacteroides pectinophilus ATCC 43243 Site: position = -103 score = 6.37791 sequence = CAATGTAAGCGCTTACATTA Gene: BACPEC_00407: Altronate oxidoreductase (EC 1.1.1.58)	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469 Gene: BRYFOR_03985: Altronate oxidoreductase (EC 1.1.1.58)	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755 Gene: DORFOR_02947: Altronate oxidoreductase (EC 1.1.1.58)	Dorea longicatena DSM 13814	* Eubacterium eligens ATCC 27750 Site: position = -105 score = 5.70207 sequence = TTATGAAAGCGCTTACATGC Site: position = -233 score = 6.51541 sequence = AAATGTAAGCGCTTACATAT Gene: EUBELI_00907: Altronate oxidoreductase (EC 1.1.1.58)	Eubacterium rectale ATCC 33656	2 Roseburia intestinalis L1-82* Site: position = -139 score = 5.2542 sequence = AAATGAAAGCAGTTTCATTA Gene: ROSINTL182_03039: Altronate oxidoreductase (EC 1.1.1.58) Gene: ROSINTL182_03038: Altronate oxidoreductase (EC 1.1.1.58)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_00434: Altronate oxidoreductase (EC 1.1.1.58)	Ruminococcus lactaris ATCC 29176	Altronate oxidoreductase (EC 1.1.1.58)

CRON 3.
pfkA	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	* Clostridiales bacterium 1_7_47_FAA Site: position = -39 score = 6.44977 sequence = TTTTGTAAGCGCTTACAATT Gene: Cbac1_010100025807: 6-phosphofructokinase (EC 2.7.1.11)	* Clostridium bolteae ATCC BAA-613 Site: position = -37 score = 6.44977 sequence = TTTTGTAAGCGCTTACAATT Gene: CLOBOL_01311: 6-phosphofructokinase (EC 2.7.1.11)	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	Eubacterium rectale ATCC 33656	Roseburia intestinalis L1-82	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176	6-phosphofructokinase (EC 2.7.1.11)

CRON 4.
uxaB2	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	* Clostridiales bacterium 1_7_47_FAA Site: position = -56 score = 6.13645 sequence = AAATGTAAGTACTTACAAAA Site: position = -156 score = 6.05098 sequence = AAATGTAAACACTTACAATT Gene: Cbac1_010100028614: Altronate oxidoreductase (EC 1.1.1.58)	* Clostridium bolteae ATCC BAA-613 Site: position = -42 score = 6.30675 sequence = AAATGTAAGCACTTACAAAA Site: position = -139 score = 5.75418 sequence = AAATGTAAATACTTACAAAA Gene: CLOBOL_06887: Altronate oxidoreductase (EC 1.1.1.58)	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	Eubacterium rectale ATCC 33656	Roseburia intestinalis L1-82	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176	Altronate oxidoreductase (EC 1.1.1.58)

CRON 5.
pgl	Bacteroides pectinophilus ATCC 43243 Gene: BACPEC_01724: Polygalacturonase (EC 3.2.1.15)	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01436: Polygalacturonase (EC 3.2.1.15)	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750 Gene: EUBELI_01594: Polygalacturonase (EC 3.2.1.15)	Eubacterium rectale ATCC 33656	Roseburia intestinalis L1-82 Gene: ROSINTL182_00330: Polygalacturonase (EC 3.2.1.15)	* Ruminococcus gnavus ATCC 29149 Site: position = -17 score = 5.51205 sequence = TAATGTAAGCTGTTACAATG Site: position = -215 score = 5.61823 sequence = AAATGTAAGTACTAACACTA Gene: RUMGNA_00427: Polygalacturonase (EC 3.2.1.15)	Ruminococcus lactaris ATCC 29176	Polygalacturonase (EC 3.2.1.15)

CRON 6.
ugl	Bacteroides pectinophilus ATCC 43243 Gene: BACPEC_02146: Unsaturated glucuronyl hydrolase (EC 3.2.1.-	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01441: Unsaturated glucuronyl hydrolase (EC 3.2.1.-	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750 Gene: EUBELI_00669: Unsaturated glucuronyl hydrolase (EC 3.2.1.-	Eubacterium rectale ATCC 33656	* Roseburia intestinalis L1-82 Site: position = -126 score = 6.33435 sequence = ATTTGTAAGCGCTTACAAAA Gene: ROSINTL182_00339: Unsaturated glucuronyl hydrolase (EC 3.2.1.-	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176	Unsaturated glucuronyl hydrolase (EC 3.2.1.-

CRON 7.
uxuB	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	* Bryantella formatexigens DSM 14469 Site: position = -78 score = 5.94932 sequence = GATTGTAAGCGCTTACATGG Site: position = -228 score = 6.31368 sequence = AAATGTAAGCGCTTACACAA Gene: BRYFOR_01978: D-mannonate oxidoreductase (EC 1.1.1.57)	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	Eubacterium rectale ATCC 33656	Roseburia intestinalis L1-82 Gene: ROSINTL182_02901: D-mannonate oxidoreductase (EC 1.1.1.57)	Ruminococcus gnavus ATCC 29149 Gene: RUMGNA_01046: D-mannonate oxidoreductase (EC 1.1.1.57)	Ruminococcus lactaris ATCC 29176	D-mannonate oxidoreductase (EC 1.1.1.57)

CRON 8.
PF02743	Bacteroides pectinophilus ATCC 43243	Blautia hansenii DSM 20583	Bryantella formatexigens DSM 14469	Clostridiales bacterium 1_7_47_FAA	Clostridium bolteae ATCC BAA-613	Clostridium nexile DSM 1787	Clostridium scindens ATCC 35704	Dorea formicigenerans ATCC 27755	Dorea longicatena DSM 13814	Eubacterium eligens ATCC 27750	Eubacterium rectale ATCC 33656	* Roseburia intestinalis L1-82 Site: position = -45 score = 6.08882 sequence = AAATGTAACCGCTTACATAA Gene: ROSINTL182_00594: hypothetical protein	Ruminococcus gnavus ATCC 29149	Ruminococcus lactaris ATCC 29176	hypothetical protein

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog UxuR - Clostridia-3

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --