Regulog ExuR - Clostridia-1

Properties
Regulator type:	Transcription factor
Regulator family:	LacI
Regulation mode:	repressor
Biological process:	Galacturonate utilization
Effector:	Galacturonate
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 20 sites [see more]

Member of regulog collections

By taxonomy - Clostridia-1
By TF family - LacI
By effector - Galacturonate
By pathway - Galacturonate utilization

Statistics of regulated genes
Genome	Genes	Operons
Clostridium butyricum 5521	7	3
Clostridium perfringens ATCC 13124
Clostridium tetani E88
Clostridium novyi NT
Clostridium acetobutylicum ATCC 824	14	7
Clostridium beijerincki NCIMB 8052	4	1
Clostridium botulinum A str. ATCC 3502
Clostridium kluyveri DSM 555

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
pelX	* Clostridium butyricum 5521 Site: position = -34 score = 5.89225 sequence = AATTGTTAACGTTAACTATA Site: position = -122 score = 5.25241 sequence = AATTGTTAACGTTAAACTTA Gene: CBY_2353: Exopolygalacturonate lyase	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	Clostridium acetobutylicum ATCC 824	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Exopolygalacturonate lyase

CRON 2.
pelL	Clostridium butyricum 5521	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	* Clostridium acetobutylicum ATCC 824 Site: position = -167 score = 5.66377 sequence = GTTTGTTAACGATAACAATA Gene: CAC0812: Pectate transeliminase, secreted	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Pectate transeliminase, secreted

CRON 3.
rhiN	* Clostridium butyricum 5521 Site: position = -197 score = 4.4807 sequence = TTTGGAAAACGTGTTCAATT Site: position = -96 score = 4.9538 sequence = AAATGTGCACGTGTGCAAAA Gene: CBY_0243: Rhamnogalacturonides degradation protein RhiN	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	* Clostridium acetobutylicum ATCC 824 Site: position = -72 score = 5.71832 sequence = TATTGATAACGTGAACACTA Site: position = -195 score = 5.6835 sequence = CTTTGTTAACGTTAACGTAA Gene: CAC0359: Rhamnogalacturonides degradation protein RhiN	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Rhamnogalacturonides degradation protein RhiN
PF02589	Clostridium butyricum 5521 Gene: CBY_0242: Domain of unknown function DUF162	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	Clostridium acetobutylicum ATCC 824 Gene: CAC0356: Domain of unknown function DUF162	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Domain of unknown function DUF162
PF01522	Clostridium butyricum 5521 Gene: CBY_0241: Polysaccharide deacetylase	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	Clostridium acetobutylicum ATCC 824 Gene: CAC0358: Polysaccharide deacetylase	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Polysaccharide deacetylase
rhiT	Clostridium butyricum 5521 Gene: CBY_0240: Putative rhamnogalacturonide transporter	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	Clostridium acetobutylicum ATCC 824 Gene: CAC0357: Putative rhamnogalacturonide transporter	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Putative rhamnogalacturonide transporter
pgl	Clostridium butyricum 5521 Gene: CBY_0239: Polygalacturonase (EC 3.2.1.15)	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	Clostridium acetobutylicum ATCC 824 Gene: CAC0355: Polygalacturonase (EC 3.2.1.15)	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Polygalacturonase (EC 3.2.1.15)

CRON 4.
mcp	Clostridium butyricum 5521	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	* Clostridium acetobutylicum ATCC 824 Site: position = -51 score = 5.25059 sequence = TTTTGTTAACGTTATCTGTA Site: position = -38 score = 4.53584 sequence = ATCTGTATACGATAACAATT Gene: CAC2774: Methyl-accepting chemotaxis protein with HAMP domain	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Methyl-accepting chemotaxis protein with HAMP domain

CRON 5.
pelA	Clostridium butyricum 5521	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	* Clostridium acetobutylicum ATCC 824 Site: position = -100 score = 5.40849 sequence = AATTGTTAACGTTAAACAAA Site: position = -42 score = 4.5557 sequence = TATGTTTATCGTAAACAAAA Site: position = -106 score = 4.46398 sequence = TAATGTAATTGTTAACGTTA Gene: CAC0804: Exopolygalacturonate lyase	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Exopolygalacturonate lyase

CRON 6.
pell	* Clostridium butyricum 5521 Site: position = -43 score = 5.95041 sequence = AATTGTTAACGATAACAATA Gene: CBY_3715: Pectate lyase, secreted, polysaccharide lyase family	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	* Clostridium acetobutylicum ATCC 824 Site: position = -46 score = 6.08787 sequence = AAATGTTAACGTTAACATAA Gene: CAP0056: Pectate lyase, secreted, polysaccharide lyase family	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Pectate lyase, secreted, polysaccharide lyase family

CRON 7.
uxaC	Clostridium butyricum 5521	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	* Clostridium acetobutylicum ATCC 824 Site: position = -121 score = 5.69303 sequence = AGTTGTTCACGTTCACAAAA Gene: CAC0692: Uronate isomerase (EC 5.3.1.12)	* Clostridium beijerincki NCIMB 8052 Site: position = -148 score = 5.76116 sequence = AGTTGTTAACGTTCACAAAA Site: position = -71 score = 4.96276 sequence = AAATGTTCACGTGAACAGGG Site: position = -39 score = 6.36682 sequence = TTTTGTTCACGTGAACAAAA Gene: Cbei_1832: Uronate isomerase (EC 5.3.1.12)	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Uronate isomerase (EC 5.3.1.12)
uxaB	Clostridium butyricum 5521 Gene: CBY_0247: Altronate oxidoreductase (EC 1.1.1.58)	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	* Clostridium acetobutylicum ATCC 824 Site: position = -42 score = 5.20613 sequence = TTTTGAACACGTGAACGTAA Site: position = -130 score = 5.41739 sequence = AAATGTTCACGTGTTCAAAA Gene: CAC0695: Altronate oxidoreductase (EC 1.1.1.58)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1833: Altronate oxidoreductase (EC 1.1.1.58)	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Altronate oxidoreductase (EC 1.1.1.58)
Cbei_4080	Clostridium butyricum 5521	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	Clostridium acetobutylicum ATCC 824	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1834: HIT family protein	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	HIT family protein
uxaT	Clostridium butyricum 5521	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	Clostridium acetobutylicum ATCC 824 Gene: CAC0694: Galacturonate transporter UxaT	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1835: Galacturonate transporter UxaT	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Galacturonate transporter UxaT
exuR	Clostridium butyricum 5521 Gene: CBY_3741: Hexuronate utilization transcriptional repressor ExuR, LacI family	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	Clostridium acetobutylicum ATCC 824 Gene: CAC0693: Hexuronate utilization transcriptional repressor ExuR, LacI family	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1831: Hexuronate utilization transcriptional repressor ExuR, LacI family	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Hexuronate utilization transcriptional repressor ExuR, LacI family
uxaA	Clostridium butyricum 5521 Gene: CBY_0246: Altronate hydrolase (EC 4.2.1.7)	Clostridium perfringens ATCC 13124	Clostridium tetani E88	Clostridium novyi NT	Clostridium acetobutylicum ATCC 824 Gene: CAC0696: Altronate hydrolase (EC 4.2.1.7)	Clostridium beijerincki NCIMB 8052	Clostridium botulinum A str. ATCC 3502	Clostridium kluyveri DSM 555	Altronate hydrolase (EC 4.2.1.7)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog ExuR - Clostridia-1

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --