Regulog PtxS - Burkholderia

Properties
Regulator type:	Transcription factor
Regulator family:	LacI
Regulation mode:	repressor
Biological process:	2-ketogluconate utilization
Effector:	2-keto-D-gluconate
Phylum:	Proteobacteria/beta
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 11 sites [see more]

Member of regulog collections

By taxonomy - Burkholderia
By TF family - LacI
By effector - 2-keto-D-gluconate
By pathway - 2-ketogluconate utilization

Statistics of regulated genes
Genome	Genes	Operons
Burkholderia cepacia AMMD	7	2
Burkholderia xenovorans LB400	7	1
Burkholderia vietnamiensis G4	7	2
Burkholderia sp. 383	7	2
Burkholderia pseudomallei K96243	4	1
Burkholderia phymatum STM815	7	1
Burkholderia mallei ATCC 23344	3	1
Burkholderia glumae BGR1	4	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
kguE	* Burkholderia cepacia AMMD Site: position = -39 score = 7.078 sequence = AAATGGAACCGGTTCCATTC Gene: Bamb_1655: Predicted epimerase/isomerase	* Burkholderia xenovorans LB400 Site: position = -52 score = 6.53653 sequence = ATTTGGAACCGGTTCCAAAT Gene: Bxe_A1979: Predicted epimerase/isomerase	* Burkholderia vietnamiensis G4 Site: position = -47 score = 7.078 sequence = AAATGGAACCGGTTCCATTC Gene: Bcep1808_1678: Predicted epimerase/isomerase	* Burkholderia sp. 383 Site: position = -37 score = 7.078 sequence = AAATGGAACCGGTTCCATTC Gene: Bcep18194_A5030: Predicted epimerase/isomerase	* Burkholderia pseudomallei K96243 Site: position = -61 score = 6.88355 sequence = GAATGGAACCGGTTCCATTT Gene: BPSL1574: Predicted epimerase/isomerase	* Burkholderia phymatum STM815 Site: position = -52 score = 5.82847 sequence = CTTTGGAACCGATTCCAAAG Gene: Bphy_1254: Predicted epimerase/isomerase	* Burkholderia mallei ATCC 23344 Site: position = -61 score = 6.93048 sequence = GAATGGAACCGGTTCCATTC Gene: BMA0960: Predicted epimerase/isomerase	* Burkholderia glumae BGR1 Site: position = -72 score = 6.61761 sequence = AACTGGAACCGGTTCCAAAT Gene: bglu_1g16220: Predicted epimerase/isomerase	Predicted epimerase/isomerase
kguK	Burkholderia cepacia AMMD Gene: Bamb_1654: 2-ketogluconate kinase (EC 2.7.1.13)	Burkholderia xenovorans LB400 Gene: Bxe_A1980: 2-ketogluconate kinase (EC 2.7.1.13)	Burkholderia vietnamiensis G4 Gene: Bcep1808_1677: 2-ketogluconate kinase (EC 2.7.1.13)	Burkholderia sp. 383 Gene: Bcep18194_A5029: 2-ketogluconate kinase (EC 2.7.1.13)	Burkholderia pseudomallei K96243 Gene: BPSL1575: 2-ketogluconate kinase (EC 2.7.1.13)	Burkholderia phymatum STM815 Gene: Bphy_1253: 2-ketogluconate kinase (EC 2.7.1.13)	Burkholderia mallei ATCC 23344 Gene: BMA0961: 2-ketogluconate kinase (EC 2.7.1.13)	Burkholderia glumae BGR1 Gene: bglu_1g16230: 2-ketogluconate kinase (EC 2.7.1.13)	2-ketogluconate kinase (EC 2.7.1.13)
kguT	Burkholderia cepacia AMMD Gene: Bamb_1653: 2-ketogluconate transporter	Burkholderia xenovorans LB400 Gene: Bxe_A1981: 2-ketogluconate transporter	Burkholderia vietnamiensis G4 Gene: Bcep1808_1676: 2-ketogluconate transporter	Burkholderia sp. 383 Gene: Bcep18194_A5028: 2-ketogluconate transporter	Burkholderia pseudomallei K96243 Gene: BPSL1576: 2-ketogluconate transporter	Burkholderia phymatum STM815 Gene: Bphy_1252: 2-ketogluconate transporter	Burkholderia mallei ATCC 23344 Gene: BMA0962: 2-ketogluconate transporter	Burkholderia glumae BGR1 Gene: bglu_1g16240: 2-ketogluconate transporter	2-ketogluconate transporter
kguD	Burkholderia cepacia AMMD Gene: Bamb_1652: 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43)	Burkholderia xenovorans LB400 Gene: Bxe_A1982: 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43)	Burkholderia vietnamiensis G4 Gene: Bcep1808_1675: 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43)	Burkholderia sp. 383 Gene: Bcep18194_A5027: 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43)	Burkholderia pseudomallei K96243 Gene: BPSL1577: 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43)	Burkholderia phymatum STM815 Gene: Bphy_1251: 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43)	Burkholderia mallei ATCC 23344	Burkholderia glumae BGR1 Gene: bglu_1g16250: 2-ketogluconate 6-phosphate reductase (EC 1.1.1.43)	2-ketogluconate 6-phosphate reductase (EC 1.1.1.43)
ptxS	Burkholderia cepacia AMMD Gene: Bamb_1651: 2-ketogluconate utilization repressor PtxS, LacI family	Burkholderia xenovorans LB400 Gene: Bxe_A1983: 2-ketogluconate utilization repressor PtxS, LacI family	Burkholderia vietnamiensis G4 Gene: Bcep1808_1674: 2-ketogluconate utilization repressor PtxS, LacI family	Burkholderia sp. 383 Gene: Bcep18194_A5026: 2-ketogluconate utilization repressor PtxS, LacI family	Burkholderia pseudomallei K96243 Gene: BPSL1578: 2-ketogluconate utilization repressor PtxS, LacI family	Burkholderia phymatum STM815 Gene: Bphy_1250: 2-ketogluconate utilization repressor PtxS, LacI family	Burkholderia mallei ATCC 23344 Gene: BMA0965: 2-ketogluconate utilization repressor PtxS, LacI family	Burkholderia glumae BGR1 Gene: bglu_1g16260: 2-ketogluconate utilization repressor PtxS, LacI family	2-ketogluconate utilization repressor PtxS, LacI family
kguM	Burkholderia cepacia AMMD Gene: Bamb_1650: Membrane protein in 2-ketogluconate utilization locus	Burkholderia xenovorans LB400 Gene: Bxe_A1984: Membrane protein in 2-ketogluconate utilization locus	Burkholderia vietnamiensis G4 Gene: Bcep1808_1673: Membrane protein in 2-ketogluconate utilization locus	Burkholderia sp. 383 Gene: Bcep18194_A5025: Membrane protein in 2-ketogluconate utilization locus	Burkholderia pseudomallei K96243 Gene: BPSL1579: Membrane protein in 2-ketogluconate utilization locus	Burkholderia phymatum STM815 Gene: Bphy_1249: Membrane protein in 2-ketogluconate utilization locus	Burkholderia mallei ATCC 23344 Gene: BMA0966: Membrane protein in 2-ketogluconate utilization locus	Burkholderia glumae BGR1 Gene: bglu_1g16270: Membrane protein in 2-ketogluconate utilization locus	Membrane protein in 2-ketogluconate utilization locus
kguX	Burkholderia cepacia AMMD Gene: Bamb_1649: Conserved hypothetical protein	Burkholderia xenovorans LB400 Gene: Bxe_A1985: Conserved hypothetical protein	Burkholderia vietnamiensis G4 Gene: Bcep1808_1672: Conserved hypothetical protein	Burkholderia sp. 383 Gene: Bcep18194_A5024: Conserved hypothetical protein	Burkholderia pseudomallei K96243 Gene: BPSL1580: Conserved hypothetical protein	Burkholderia phymatum STM815 Gene: Bphy_1248: Conserved hypothetical protein	Burkholderia mallei ATCC 23344 Gene: BMA0967: Conserved hypothetical protein	Burkholderia glumae BGR1 Gene: bglu_1g16280: Conserved hypothetical protein	Conserved hypothetical protein

CRON 2.
gadC	* Burkholderia cepacia AMMD Site: position = -310 score = 5.77195 sequence = CAATGGAACCGGTTCTATCT Gene: Bamb_3645: Gluconate 2-dehydrogenase (EC 1.1.99.3), membrane-bound, gamma subunit	Burkholderia xenovorans LB400	* Burkholderia vietnamiensis G4 Site: position = -270 score = 6.78613 sequence = CAATGGAACCGGTTCCATTT Gene: Bcep1808_4793: Gluconate 2-dehydrogenase (EC 1.1.99.3), membrane-bound, gamma subunit	* Burkholderia sp. 383 Site: position = -337 score = 5.98228 sequence = TGATGGAACCGGTTCCATAT Gene: Bcep18194_B1794: Gluconate 2-dehydrogenase (EC 1.1.99.3), membrane-bound, gamma subunit	Burkholderia pseudomallei K96243	Burkholderia phymatum STM815	Burkholderia mallei ATCC 23344	Burkholderia glumae BGR1	Gluconate 2-dehydrogenase (EC 1.1.99.3), membrane-bound, gamma subunit
gadB	Burkholderia cepacia AMMD Gene: Bamb_3646: Gluconate 2-dehydrogenase (EC 1.1.99.3), membrane-bound flavoprotein subunit	Burkholderia xenovorans LB400	Burkholderia vietnamiensis G4 Gene: Bcep1808_4794: Gluconate 2-dehydrogenase (EC 1.1.99.3), membrane-bound flavoprotein subunit	Burkholderia sp. 383 Gene: Bcep18194_B1793: Gluconate 2-dehydrogenase (EC 1.1.99.3), membrane-bound flavoprotein subunit	Burkholderia pseudomallei K96243	Burkholderia phymatum STM815	Burkholderia mallei ATCC 23344	Burkholderia glumae BGR1	Gluconate 2-dehydrogenase (EC 1.1.99.3), membrane-bound flavoprotein subunit
gadA	Burkholderia cepacia AMMD Gene: Bamb_3647: Gluconate 2-dehydrogenase (EC 1.1.99.3), membrane-bound, cytochrome c subunit	Burkholderia xenovorans LB400	Burkholderia vietnamiensis G4 Gene: Bcep1808_4795: Gluconate 2-dehydrogenase (EC 1.1.99.3), membrane-bound, cytochrome c subunit	Burkholderia sp. 383 Gene: Bcep18194_B1792: Gluconate 2-dehydrogenase (EC 1.1.99.3), membrane-bound, cytochrome c subunit	Burkholderia pseudomallei K96243	Burkholderia phymatum STM815	Burkholderia mallei ATCC 23344	Burkholderia glumae BGR1	Gluconate 2-dehydrogenase (EC 1.1.99.3), membrane-bound, cytochrome c subunit

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog PtxS - Burkholderia

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --