Regulog HTCS_Hep - Bacteroidaceae

Properties
Regulator type:	Transcription factor
Regulator family:	[Other]
Regulation mode:	activator (repressor)
Biological process:	Heparin utilization
Effector:	Heparin
Phylum:	Bacteroidetes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 10 sites [see more]

Member of regulog collections

By taxonomy - Bacteroidaceae
By TF family - [Other]
By effector - Heparin
By pathway - Heparin utilization

Statistics of regulated genes
Genome	Genes	Operons
Bacteroides cellulosilyticus DSM 14838
Bacteroides coprophilus DSM 18228
Bacteroides dorei DSM 17855
Bacteroides eggerthii DSM 20697	4	2
Bacteroides fragilis NCTC 9343
Bacteroides ovatus ATCC 8483	12	3
Bacteroides plebeius DSM 17135
Bacteroides stercoris ATCC 43183	6	2
Bacteroides thetaiotaomicron VPI-5482	12	3
Bacteroides uniformis ATCC 8492
Bacteroides vulgatus ATCC 8482

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes												Function

CRON 1.
hepC	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_00780: Heparin lyase I / Heparinase I (EC 4.2.2.7)	Bacteroides coprophilus DSM 18228	Bacteroides dorei DSM 17855	* Bacteroides eggerthii DSM 20697 Site: position = -94 score = 8.41062 sequence = ACAAATATAG-(11)-ACAAATAGGA Gene: BACEGG_00070: Heparin lyase I / Heparinase I (EC 4.2.2.7)	Bacteroides fragilis NCTC 9343	* Bacteroides ovatus ATCC 8483 Site: position = -92 score = 8.46113 sequence = ACAAATGTGA-(11)-ACAAAAGAAA Gene: BACOVA_05497: Heparin lyase I / Heparinase I (EC 4.2.2.7)	Bacteroides plebeius DSM 17135	* Bacteroides stercoris ATCC 43183 Site: position = -96 score = 7.85472 sequence = ACAAATATAG-(11)-ACAAATAGGG Gene: BACSTE_03699: Heparin lyase I / Heparinase I (EC 4.2.2.7)	* Bacteroides thetaiotaomicron VPI-5482 Site: position = -140 score = 8.30077 sequence = ACAAATGTGA-(11)-ACAAACGAAA Gene: BT4675: Heparin lyase I / Heparinase I (EC 4.2.2.7)	Bacteroides uniformis ATCC 8492	Bacteroides vulgatus ATCC 8482	Heparin lyase I / Heparinase I (EC 4.2.2.7)

CRON 2.
hepL1	Bacteroides cellulosilyticus DSM 14838	Bacteroides coprophilus DSM 18228	Bacteroides dorei DSM 17855	Bacteroides eggerthii DSM 20697	Bacteroides fragilis NCTC 9343	* Bacteroides ovatus ATCC 8483 Site: position = -148 score = 7.57771 sequence = ACATTATTAA-(11)-ACAATATTAA Gene: BACOVA_05478: Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)	Bacteroides plebeius DSM 17135	* Bacteroides stercoris ATCC 43183 Site: position = -148 score = 8.69366 sequence = ACAAATACGA-(11)-ACAAATTTAA Gene: BACSTE_03702: Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)	* Bacteroides thetaiotaomicron VPI-5482 Site: position = -149 score = 8.51968 sequence = ACAAAAACAA-(11)-ACAAATTTGA Gene: BT4662: Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)	Bacteroides uniformis ATCC 8492	Bacteroides vulgatus ATCC 8482	Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)
BT4661	Bacteroides cellulosilyticus DSM 14838	Bacteroides coprophilus DSM 18228	Bacteroides dorei DSM 17855	* Bacteroides eggerthii DSM 20697 Site: position = -153 score = 8.18803 sequence = ACAAATCTAA-(11)-ACAACTTTGA Gene: BACEGG_00066: Hypothetical protein, presumably involved in heparin utilization	Bacteroides fragilis NCTC 9343	Bacteroides ovatus ATCC 8483 Gene: BACOVA_05477: Hypothetical protein, presumably involved in heparin utilization	Bacteroides plebeius DSM 17135	Bacteroides stercoris ATCC 43183 Gene: BACSTE_03703: Hypothetical protein, presumably involved in heparin utilization	Bacteroides thetaiotaomicron VPI-5482 Gene: BT4661: Hypothetical protein, presumably involved in heparin utilization	Bacteroides uniformis ATCC 8492	Bacteroides vulgatus ATCC 8482	Hypothetical protein, presumably involved in heparin utilization
susC_Hep-1	Bacteroides cellulosilyticus DSM 14838	Bacteroides coprophilus DSM 18228	Bacteroides dorei DSM 17855	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00065: TonB-dependent outer membrane transporter of heparin oligosaccharides	Bacteroides fragilis NCTC 9343	Bacteroides ovatus ATCC 8483 Gene: BACOVA_05476: TonB-dependent outer membrane transporter of heparin oligosaccharides	Bacteroides plebeius DSM 17135	2 Bacteroides stercoris ATCC 43183 Gene: BACSTE_03705: TonB-dependent outer membrane transporter of heparin oligosaccharides Gene: BACSTE_03704: TonB-dependent outer membrane transporter of heparin oligosaccharides	Bacteroides thetaiotaomicron VPI-5482 Gene: BT4660: TonB-dependent outer membrane transporter of heparin oligosaccharides	Bacteroides uniformis ATCC 8492	Bacteroides vulgatus ATCC 8482	TonB-dependent outer membrane transporter of heparin oligosaccharides
susD_Hep	Bacteroides cellulosilyticus DSM 14838	Bacteroides coprophilus DSM 18228	Bacteroides dorei DSM 17855	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00064: Outer membrane polysaccharide binding protein for heparin oligosaccharides	Bacteroides fragilis NCTC 9343	Bacteroides ovatus ATCC 8483 Gene: BACOVA_05475: Outer membrane polysaccharide binding protein for heparin oligosaccharides	Bacteroides plebeius DSM 17135	Bacteroides stercoris ATCC 43183 Gene: BACSTE_03706: Outer membrane polysaccharide binding protein for heparin oligosaccharides	Bacteroides thetaiotaomicron VPI-5482 Gene: BT4659: Outer membrane polysaccharide binding protein for heparin oligosaccharides	Bacteroides uniformis ATCC 8492	Bacteroides vulgatus ATCC 8482	Outer membrane polysaccharide binding protein for heparin oligosaccharides

CRON 3.
hepH	Bacteroides cellulosilyticus DSM 14838	Bacteroides coprophilus DSM 18228	Bacteroides dorei DSM 17855	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00062: Glucuronyl hydrolase ( 3.2.1.-)	Bacteroides fragilis NCTC 9343	* Bacteroides ovatus ATCC 8483 Site: position = -140 score = 8.42532 sequence = AGAAATTTAA-(11)-ACAAAATCAA Gene: BACOVA_05474: Glucuronyl hydrolase ( 3.2.1.-)	Bacteroides plebeius DSM 17135	Bacteroides stercoris ATCC 43183 Gene: BACSTE_03707: Glucuronyl hydrolase ( 3.2.1.-)	* Bacteroides thetaiotaomicron VPI-5482 Site: position = -140 score = 7.99402 sequence = AGAATATTAA-(11)-ACAAATTCAA Gene: BT4658: Glucuronyl hydrolase ( 3.2.1.-)	Bacteroides uniformis ATCC 8492	Bacteroides vulgatus ATCC 8482	Glucuronyl hydrolase ( 3.2.1.-)
hepL2	Bacteroides cellulosilyticus DSM 14838	Bacteroides coprophilus DSM 18228	Bacteroides dorei DSM 17855	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00061: Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)	Bacteroides fragilis NCTC 9343	Bacteroides ovatus ATCC 8483 Gene: BACOVA_05473: Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)	Bacteroides plebeius DSM 17135	Bacteroides stercoris ATCC 43183 Gene: BACSTE_03708: Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)	Bacteroides thetaiotaomicron VPI-5482 Gene: BT4657: Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)	Bacteroides uniformis ATCC 8492	Bacteroides vulgatus ATCC 8482	Heparinase III protein / Heparitin sulfate lyase (EC 4.2.2.8)
nagS	Bacteroides cellulosilyticus DSM 14838	Bacteroides coprophilus DSM 18228	Bacteroides dorei DSM 17855	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00060: N-acetylglucosamine-6-sulfatase (EC 3.1.6.14)	Bacteroides fragilis NCTC 9343	Bacteroides ovatus ATCC 8483 Gene: BACOVA_05472: N-acetylglucosamine-6-sulfatase (EC 3.1.6.14)	Bacteroides plebeius DSM 17135	Bacteroides stercoris ATCC 43183 Gene: BACSTE_03709: N-acetylglucosamine-6-sulfatase (EC 3.1.6.14)	Bacteroides thetaiotaomicron VPI-5482 Gene: BT4656: N-acetylglucosamine-6-sulfatase (EC 3.1.6.14)	Bacteroides uniformis ATCC 8492	Bacteroides vulgatus ATCC 8482	N-acetylglucosamine-6-sulfatase (EC 3.1.6.14)
nagX	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_00769: Conserved hypothetical protein	Bacteroides coprophilus DSM 18228	Bacteroides dorei DSM 17855	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00059: Conserved hypothetical protein	Bacteroides fragilis NCTC 9343	Bacteroides ovatus ATCC 8483 Gene: BACOVA_05471: Conserved hypothetical protein	Bacteroides plebeius DSM 17135	Bacteroides stercoris ATCC 43183 Gene: BACSTE_03710: Conserved hypothetical protein	Bacteroides thetaiotaomicron VPI-5482 Gene: BT4655: Conserved hypothetical protein	Bacteroides uniformis ATCC 8492	Bacteroides vulgatus ATCC 8482	Conserved hypothetical protein
nagK	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_00768: N-acetylglucosamine kinase (EC 2.7.1.59)	Bacteroides coprophilus DSM 18228	Bacteroides dorei DSM 17855	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00058: N-acetylglucosamine kinase (EC 2.7.1.59)	Bacteroides fragilis NCTC 9343	Bacteroides ovatus ATCC 8483 Gene: BACOVA_05470: N-acetylglucosamine kinase (EC 2.7.1.59)	Bacteroides plebeius DSM 17135	Bacteroides stercoris ATCC 43183 Gene: BACSTE_03711: N-acetylglucosamine kinase (EC 2.7.1.59)	Bacteroides thetaiotaomicron VPI-5482 Gene: BT4654: N-acetylglucosamine kinase (EC 2.7.1.59)	Bacteroides uniformis ATCC 8492	Bacteroides vulgatus ATCC 8482	N-acetylglucosamine kinase (EC 2.7.1.59)
nagP	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_00767: N-acetylglucosamine transporter	Bacteroides coprophilus DSM 18228	Bacteroides dorei DSM 17855	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00057: N-acetylglucosamine transporter	Bacteroides fragilis NCTC 9343	Bacteroides ovatus ATCC 8483 Gene: BACOVA_05469: N-acetylglucosamine transporter	Bacteroides plebeius DSM 17135	Bacteroides stercoris ATCC 43183 Gene: BACSTE_03712: N-acetylglucosamine transporter	Bacteroides thetaiotaomicron VPI-5482 Gene: BT4653: N-acetylglucosamine transporter	Bacteroides uniformis ATCC 8492	Bacteroides vulgatus ATCC 8482	N-acetylglucosamine transporter
hepE	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_00766: Predicted heparin lyase	Bacteroides coprophilus DSM 18228	Bacteroides dorei DSM 17855	Bacteroides eggerthii DSM 20697	Bacteroides fragilis NCTC 9343	Bacteroides ovatus ATCC 8483 Gene: BACOVA_05468: Predicted heparin lyase	Bacteroides plebeius DSM 17135	Bacteroides stercoris ATCC 43183	Bacteroides thetaiotaomicron VPI-5482 Gene: BT4652: Predicted heparin lyase	Bacteroides uniformis ATCC 8492	Bacteroides vulgatus ATCC 8482	Predicted heparin lyase

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog HTCS_Hep - Bacteroidaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --