Regulog Rex - Clostridia-2
| Regulator type: | Transcription factor |
| Regulator family: | Rex |
| Regulation mode: | repressor |
| Biological process: | Energy metabolism |
| Effector: | NADH |
| Phylum: | Firmicutes |
| Visualization: | |
|
Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Clostridia-2
- By TF family - Rex
- By effector - NADH
- By pathway - Energy metabolism
| Genome | Genes | Operons |
|---|---|---|
| Clostridium bartlettii DSM 16795 | 19 | 9 |
| Clostridium difficile 630 | 23 | 9 |
| Clostridium hiranonis DSM 13275 | 6 | 4 |
| Genes | Function | |||
|---|---|---|---|---|
| CRON 1. | ||||
| grdE |
|
*
Clostridium difficile 630 Site: position = -264 score = 5.46615 sequence = TTGATAAATTATTAACAT Site: position = -187 score = 4.53735 sequence = TTGTTAAAAAAATAATTT Gene: CD2354: Glycine reductase component B beta subunit (EC 1.21.4.2) / Glycine reductase component B alpha subunit (EC 1.21.4.2) |
|
Glycine reductase component B beta subunit (EC 1.21.4.2) / Glycine reductase component B alpha subunit (EC 1.21.4.2) |
| CRON 2. | ||||
| glcA |
*
Clostridium bartlettii DSM 16795 Site: position = -119 score = 5.17027 sequence = ATGTTAATAAATAAACAA Site: position = -138 score = 4.26725 sequence = TTTTTATTAATTTAAAAT Gene: CLOBAR_02282: Glycolate permease |
|
|
Glycolate permease |
| PF09861 |
Gene: CLOBAR_02281: Protein of unknown function DUF2088 |
*
Clostridium difficile 630 Site: position = -113 score = 4.04182 sequence = TTGTTATAAAATAAATTA Gene: CD1170: Protein of unknown function DUF2088 |
|
Protein of unknown function DUF2088 |
| etfB |
2
Clostridium bartlettii DSM 16795 Gene: CLOBAR_02279: Electron transfer flavoprotein beta-subunit Gene: CLOBAR_02280: Electron transfer flavoprotein beta-subunit |
Gene: CD1171: Electron transfer flavoprotein beta-subunit |
|
Electron transfer flavoprotein beta-subunit |
| etfA |
Gene: CLOBAR_02278: Electron transfer flavoprotein alpha-subunit |
Gene: CD1172: Electron transfer flavoprotein alpha-subunit |
|
Electron transfer flavoprotein alpha-subunit |
| glcD |
Gene: CLOBAR_02277: Glycolate oxidase (EC 1.1.99.14), FAD/FMN-containing |
Gene: CD1173: Glycolate oxidase (EC 1.1.99.14), FAD/FMN-containing |
|
Glycolate oxidase (EC 1.1.99.14), FAD/FMN-containing |
| CRON 3. | ||||
| rex |
*2
Clostridium bartlettii DSM 16795 Site: position = -37 score = 3.98978 sequence = TTGTTATGAAAATATTAA Site: position = -99 score = 4.10187 sequence = TTGGTATAATATAATCAA Gene: CLOBAR_00711: Redox-sensitive transcriptional regulator Rex Site: position = -156 score = 4.34683 sequence = ATAATATATTATTAACTA Gene: CLOBAR_01830: Redox-sensitive transcriptional regulator Rex |
*
Clostridium difficile 630 Site: position = -96 score = 4.5729 sequence = TTGATATAATATAATCAA Gene: CD0171: Redox-sensitive transcriptional regulator Rex |
*
Clostridium hiranonis DSM 13275 Site: position = -55 score = 4.33113 sequence = ATGTTATATAATAAACCA Site: position = -101 score = 4.01189 sequence = TTGATATAATATATTCAA Gene: CLOHIR_00042: Redox-sensitive transcriptional regulator Rex |
Redox-sensitive transcriptional regulator Rex |
| CRON 4. | ||||
| bcd2 |
|
*
Clostridium difficile 630 Site: position = -193 score = 5.04578 sequence = TTGATTTTAAATTAACAA Gene: CD1054: Butyryl-CoA dehydrogenase (EC 1.3.99.2) |
|
Butyryl-CoA dehydrogenase (EC 1.3.99.2) |
| etfB2 |
|
Gene: CD1055: Electron transfer flavoprotein, beta subunit |
|
Electron transfer flavoprotein, beta subunit |
| etfA2 |
|
Gene: CD1056: Electron transfer flavoprotein, alpha subunit |
|
Electron transfer flavoprotein, alpha subunit |
| crt2 |
|
Gene: CD1057: 3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55) |
|
3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55) |
| hbd |
|
Gene: CD1058: 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) |
|
3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) |
| thlA1 |
|
Gene: CD1059: Acetyl-CoA acetyltransferase (EC 2.3.1.9) |
|
Acetyl-CoA acetyltransferase (EC 2.3.1.9) |
| CRON 5. | ||||
| fprA |
|
*
Clostridium difficile 630 Site: position = -63 score = 5.39866 sequence = TTGTTTAAAATATAACAA Gene: CD1623: H(2)O-forming NADH oxidase (EC 1.6.3.-) |
|
H(2)O-forming NADH oxidase (EC 1.6.3.-) |
| CRON 6. | ||||
| CD2344 |
|
*
Clostridium difficile 630 Site: position = -190 score = 4.56384 sequence = TTGTTAATTAAATCATAA Site: position = -129 score = 5.40604 sequence = ATGTTAATTTAATAACAA Site: position = -66 score = 5.21897 sequence = TTGTTAATTTAATAACGA Gene: CD2344: putative transport protein |
|
putative transport protein |
| cat1 |
|
Gene: CD2343: Succinyl-CoA:coenzyme A transferase (EC 2.8.3.-) |
|
Succinyl-CoA:coenzyme A transferase (EC 2.8.3.-) |
| sucD |
|
Gene: CD2342: Succinate-semialdehyde dehydrogenase, CoA-dependent |
|
Succinate-semialdehyde dehydrogenase, CoA-dependent |
| abfD |
|
Gene: CD2341: 4-hydroxybutanoyl-CoA dehydratase (EC 4.2.1.-) |
|
4-hydroxybutanoyl-CoA dehydratase (EC 4.2.1.-) |
| CD2340 |
|
Gene: CD2340: hypothetical protein |
|
hypothetical protein |
| abfT |
|
Gene: CD2339: 4-hydroxybutyrate:acetyl-CoA CoA transferase (EC 2.3.1.-) |
|
4-hydroxybutyrate:acetyl-CoA CoA transferase (EC 2.3.1.-) |
| 4hbd |
|
Gene: CD2338: NAD-dependent 4-hydroxybutyrate dehydrogenase (EC 1.1.1.61) |
|
NAD-dependent 4-hydroxybutyrate dehydrogenase (EC 1.1.1.61) |
| CRON 7. | ||||
| nadA |
*
Clostridium bartlettii DSM 16795 Site: position = -113 score = 4.68854 sequence = AAATTAAAAATTTAACTA Gene: CLOBAR_00531: Quinolinate synthetase (EC 4.1.99.-) |
Gene: CD2372: Quinolinate synthetase (EC 4.1.99.-) |
*
Clostridium hiranonis DSM 13275 Site: position = -210 score = 5.53742 sequence = ATGATAAAAAAATAACAA Site: position = -38 score = 5.40536 sequence = TAGATAAAAAAATAACAA Gene: CLOHIR_00157: Quinolinate synthetase (EC 4.1.99.-) |
Quinolinate synthetase (EC 4.1.99.-) |
| nadB |
Gene: CLOBAR_00532: L-aspartate oxidase (EC 1.4.3.16) |
Gene: CD2371: L-aspartate oxidase (EC 1.4.3.16) |
Gene: CLOHIR_00158: L-aspartate oxidase (EC 1.4.3.16) |
L-aspartate oxidase (EC 1.4.3.16) |
| nadC |
Gene: CLOBAR_00533: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) |
Gene: CD2370: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) |
Gene: CLOHIR_00159: Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) |
Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) |
| CRON 8. | ||||
| hydC |
*2
Clostridium bartlettii DSM 16795 Site: position = -125 score = 4.40824 sequence = TATTTAAATTTTTAAAAA Site: position = -169 score = 4.8771 sequence = ATGTTAAAAAAGTATCAT Gene: CLOBAR_00902: NAD-reducing Fe-hydrogenase, subunit HydC (EC 1.12.7.2) Site: position = -128 score = 4.69586 sequence = TAGATAATTAAATAAAAA Gene: CLOBAR_00255: NAD-reducing Fe-hydrogenase, subunit HydC (EC 1.12.7.2) |
|
|
NAD-reducing Fe-hydrogenase, subunit HydC (EC 1.12.7.2) |
| hydB |
2
Clostridium bartlettii DSM 16795 Gene: CLOBAR_00256: NAD-reducing Fe-hydrogenase, subunit HydB (EC 1.12.7.2) Gene: CLOBAR_00901: NAD-reducing Fe-hydrogenase, subunit HydB (EC 1.12.7.2) |
|
|
NAD-reducing Fe-hydrogenase, subunit HydB (EC 1.12.7.2) |
| hydA |
Gene: CLOBAR_00900: NAD-reducing Fe-hydrogenase, subunit HydA (EC 1.12.7.2) |
|
|
NAD-reducing Fe-hydrogenase, subunit HydA (EC 1.12.7.2) |
| CRON 9. | ||||
| phf1 |
|
|
*
Clostridium hiranonis DSM 13275 Site: position = -107 score = 4.81147 sequence = ATGTTAAAAATATAAAGA Site: position = -87 score = 5.08872 sequence = TTGATAAAAAAATGACAA Gene: CLOHIR_00139: Fe-hydrogenase (EC 1.12.7.2) |
Fe-hydrogenase (EC 1.12.7.2) |
| CRON 10. | ||||
| CD2707 |
*
Clostridium bartlettii DSM 16795 Site: position = -91 score = 4.90725 sequence = ACGTTAAGAATTTAACAA Gene: CLOBAR_02221: Transport protein, MFS family |
*
Clostridium difficile 630 Site: position = -34 score = 5.74236 sequence = ATGTTAATAAATTAACAA Gene: CD2707: Transport protein, MFS family |
Gene: CLOHIR_00106: Transport protein, MFS family |
Transport protein, MFS family |
| CRON 11. | ||||
| adhE |
*
Clostridium bartlettii DSM 16795 Site: position = -130 score = 5.26195 sequence = ATGTTAAACAAATAACAA Site: position = -106 score = 4.77526 sequence = AGGTTAATAATATAACAT Site: position = -188 score = 5.53742 sequence = ATGATAAAAAAATAACAA Gene: CLOBAR_00502: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10) |
*2
Clostridium difficile 630 Gene: CD0334: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10) Site: position = -146 score = 5.09002 sequence = ATGTTAAAAAAATAACTT Site: position = -103 score = 5.56157 sequence = ATGTTAATAAATTAACAT Gene: CD2966: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10) |
*
Clostridium hiranonis DSM 13275 Site: position = -209 score = 5.27221 sequence = ATGATAAAAAAATATCAA Gene: CLOHIR_00687: Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10) |
Alcohol dehydrogenase (EC 1.1.1.1), Fe-dependent; Acetaldehyde dehydrogenase (EC 1.2.1.10) |
| CRON 12. | ||||
| lldD |
*
Clostridium bartlettii DSM 16795 Site: position = -94 score = 5.49793 sequence = ATGTTAAAAAAATAACAT Gene: CLOBAR_01995: L-lactate dehydrogenase |
|
|
L-lactate dehydrogenase |
| CRON 13. | ||||
| noxE |
Gene: CLOBAR_01035: NADH oxidase (EC 1.6.99.3) |
*
Clostridium difficile 630 Site: position = -112 score = 5.23654 sequence = ATGTTAAATAAATAACTA Gene: CD2540: NADH oxidase (EC 1.6.99.3) |
|
NADH oxidase (EC 1.6.99.3) |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |