Regulog CzcR1 - Lactobacillaceae

Properties
Regulator type:	Transcription factor
Regulator family:	ArsR
Regulation mode:	repressor
Biological process:	Zinc resistance; Cobalt resistance; Cadmium resistance
Effector:
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 10 sites [see more]

Member of regulog collections

By taxonomy - Lactobacillaceae
By trascription factor - CzrA
By TF family - ArsR
By pathway - Zinc resistance
By pathway - Cobalt resistance
By pathway - Cadmium resistance

Statistics of regulated genes
Genome	Genes	Operons
Lactobacillus acidophilus NCFM
Lactobacillus brevis ATCC 367
Lactobacillus casei ATCC 334
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	2	2
Lactobacillus fermentum IFO 3956
Lactobacillus helveticus DPC 4571
Lactobacillus johnsonii NCC 533	2	2
Lactobacillus plantarum WCFS1
Lactobacillus reuteri JCM 1112	2	1
Lactobacillus rhamnosus GG
Lactobacillus sakei subsp. sakei 23K
Lactobacillus salivarius subsp. salivarius UCC118
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293
Oenococcus oeni PSU-1
Pediococcus pentosaceus ATCC 25745

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
czcD	Lactobacillus acidophilus NCFM Gene: LBA0340: Cobalt-zinc-cadmium resistance protein CzcD	Lactobacillus brevis ATCC 367 Gene: LVIS_1719: Cobalt-zinc-cadmium resistance protein CzcD	Lactobacillus casei ATCC 334	* Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Site: position = -76 score = 6.39097 sequence = ATATACCAAAAATGATATAT Site: position = -113 score = 4.97513 sequence = GTATATTATTTTTGTAATAT Gene: LBUL_1220: Cobalt-zinc-cadmium resistance protein CzcD	Lactobacillus fermentum IFO 3956 Gene: LAF_1544: Cobalt-zinc-cadmium resistance protein CzcD	Lactobacillus helveticus DPC 4571 Gene: lhv_0353: Cobalt-zinc-cadmium resistance protein CzcD	* Lactobacillus johnsonii NCC 533 Site: position = -35 score = 6.27815 sequence = GTATACCAAATTCGATATAT Site: position = -72 score = 6.12555 sequence = ATATATCAAAAATGGAATAT Gene: LJ0377: Cobalt-zinc-cadmium resistance protein CzcD	Lactobacillus plantarum WCFS1	Lactobacillus reuteri JCM 1112 Gene: LAR_1416: Cobalt-zinc-cadmium resistance protein CzcD	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Cobalt-zinc-cadmium resistance protein CzcD

CRON 2.
cadD1	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367 Gene: LVIS_0221: Predicted permease, cadmium resistance protein	Lactobacillus casei ATCC 334	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956 Gene: LAF_0146: Predicted permease, cadmium resistance protein	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_2998: Predicted permease, cadmium resistance protein	* Lactobacillus reuteri JCM 1112 Site: position = -60 score = 6.51911 sequence = ATATATCAAATTCGATATAT Site: position = -33 score = 6.32256 sequence = GTATATCGAATTTGATATAT Gene: LAR_1705: Predicted permease, cadmium resistance protein	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Predicted permease, cadmium resistance protein
czcR1	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	Lactobacillus casei ATCC 334	* Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Site: position = -88 score = 6.39097 sequence = ATATATCATTTTTGGTATAT Site: position = -51 score = 4.97513 sequence = ATATTACAAAAATAATATAC Gene: LBUL_1221: Cobalt-zinc-cadmium resistance transcriptional regulator CzcR1, ArsR family	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	* Lactobacillus johnsonii NCC 533 Site: position = -40 score = 6.12555 sequence = ATATTCCATTTTTGATATAT Site: position = -77 score = 6.27815 sequence = ATATATCGAATTTGGTATAC Gene: LJ0376: Cobalt-zinc-cadmium resistance transcriptional regulator CzcR1, ArsR family	Lactobacillus plantarum WCFS1	Lactobacillus reuteri JCM 1112 Gene: LAR_1706: Cobalt-zinc-cadmium resistance transcriptional regulator CzcR1, ArsR family	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745	Cobalt-zinc-cadmium resistance transcriptional regulator CzcR1, ArsR family

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog CzcR1 - Lactobacillaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --