Regulog PaaR - Corynebacteriaceae

Properties
Regulator type:	Transcription factor
Regulator family:	TetR
Regulation mode:	repressor
Biological process:	Phenylacetic acid degradation
Effector:	Phenylacetyl-CoA
Phylum:	Actinobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 14 sites [see more]

Member of regulog collections

By taxonomy - Corynebacteriaceae
By trascription factor - PaaR
By TF family - TetR
By effector - Phenylacetyl-CoA
By pathway - Phenylacetic acid degradation

Statistics of regulated genes
Genome	Genes	Operons
Corynebacterium amycolatum SK46
Corynebacterium aurimucosum ATCC 700975
Corynebacterium diphtheriae NCTC 13129
Corynebacterium efficiens YS-314	18	7
Corynebacterium glutamicum ATCC 13032
Corynebacterium jeikeium K411
Corynebacterium kroppenstedtii DSM 44385
Corynebacterium urealyticum DSM 7109

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
paaA	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	* Corynebacterium efficiens YS-314 Site: position = -128 score = 6.3943 sequence = ACTGACCGGGCGGTCGGTTAGT Site: position = -132 score = 4.56481 sequence = ATATACTGACCGGGCGGTCGGT Gene: CE0667: Phenylacetate-CoA oxygenase, PaaA subunit	Corynebacterium glutamicum ATCC 13032	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Phenylacetate-CoA oxygenase, PaaA subunit
paaB	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	Corynebacterium efficiens YS-314 Gene: CE0668: Phenylacetate-CoA oxygenase, PaaB subunit	Corynebacterium glutamicum ATCC 13032	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Phenylacetate-CoA oxygenase, PaaB subunit
paaC	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	Corynebacterium efficiens YS-314 Gene: CE0669: Phenylacetate-CoA oxygenase, PaaC subunit	Corynebacterium glutamicum ATCC 13032	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Phenylacetate-CoA oxygenase, PaaC subunit
paaD	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	Corynebacterium efficiens YS-314 Gene: CE0670: Phenylacetate-CoA oxygenase, PaaD subunit	Corynebacterium glutamicum ATCC 13032	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Phenylacetate-CoA oxygenase, PaaD subunit
paaE	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	Corynebacterium efficiens YS-314 Gene: CE0671: Probable phenylacetic acid degradation NADH oxidoreductase paaE (EC 1.-.-.-)	Corynebacterium glutamicum ATCC 13032	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Probable phenylacetic acid degradation NADH oxidoreductase paaE (EC 1.-.-.-)
paaG	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	Corynebacterium efficiens YS-314 Gene: CE0672: Enoyl-CoA hydratase (EC 4.2.1.17)	Corynebacterium glutamicum ATCC 13032	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Enoyl-CoA hydratase (EC 4.2.1.17)
paaJ	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	Corynebacterium efficiens YS-314 Gene: CE0673: Beta-ketoadipyl CoA thiolase (EC 2.3.1.-)	Corynebacterium glutamicum ATCC 13032	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Beta-ketoadipyl CoA thiolase (EC 2.3.1.-)
paaF	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	Corynebacterium efficiens YS-314 Gene: CE0674: Enoyl-CoA hydratase (EC 4.2.1.17)	Corynebacterium glutamicum ATCC 13032	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Enoyl-CoA hydratase (EC 4.2.1.17)
paaH	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	Corynebacterium efficiens YS-314 Gene: CE0675: 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157)	Corynebacterium glutamicum ATCC 13032	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157)

CRON 2.
paaK	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	* Corynebacterium efficiens YS-314 Site: position = -180 score = 4.9823 sequence = ACCAACTTACCGACTGGTCAGT Site: position = -176 score = 5.13171 sequence = ACTTACCGACTGGTCAGTTGGT Site: position = -172 score = 4.57525 sequence = ACCGACTGGTCAGTTGGTAAAT Gene: CE0663: Phenylacetate-coenzyme A ligase (EC 6.2.1.30)	Corynebacterium glutamicum ATCC 13032	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Phenylacetate-coenzyme A ligase (EC 6.2.1.30)
paaT	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	Corynebacterium efficiens YS-314 Gene: CE0662: predicted phylacetic acid transporter	Corynebacterium glutamicum ATCC 13032	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	predicted phylacetic acid transporter

CRON 3.
paaI	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	* Corynebacterium efficiens YS-314 Site: position = -58 score = 5.35932 sequence = TACTACCGTCCATTCGGTAAGT Gene: CE0666: Phenylacetic acid degradation protein PaaI, thioesterase	Corynebacterium glutamicum ATCC 13032	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Phenylacetic acid degradation protein PaaI, thioesterase

CRON 4.
paaZ	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	* Corynebacterium efficiens YS-314 Site: position = -121 score = 5.96546 sequence = ACTGACCGGCCGTTCGGTAACT Site: position = -125 score = 5.08965 sequence = AATTACTGACCGGCCGTTCGGT Gene: CE0677: Aldehyde dehydrogenase (EC 1.2.1.3), PaaZ	Corynebacterium glutamicum ATCC 13032	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Aldehyde dehydrogenase (EC 1.2.1.3), PaaZ

CRON 5.
paaY	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	* Corynebacterium efficiens YS-314 Site: position = -47 score = 6.58933 sequence = AGTTACCGAACGGCCGGTCAGT Site: position = -43 score = 5.15048 sequence = ACCGAACGGCCGGTCAGTAATT Gene: CE0676: hypothetical protein	Corynebacterium glutamicum ATCC 13032	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	hypothetical protein

CRON 6.
hisE	Corynebacterium amycolatum SK46 Gene: CORAM0001_0989: Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Corynebacterium aurimucosum ATCC 700975 Gene: cauri_1253: Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Corynebacterium diphtheriae NCTC 13129 Gene: DIP1257: Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	* Corynebacterium efficiens YS-314 Site: position = -23 score = 6.01175 sequence = AACAACCGCACGATCGGTATGT Gene: CE1635: Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Corynebacterium glutamicum ATCC 13032 Gene: cg1699: Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385 Gene: ckrop_0917: Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Corynebacterium urealyticum DSM 7109 Gene: cur_1034: Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)	Phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31)
hisG	Corynebacterium amycolatum SK46 Gene: CORAM0001_0990: ATP phosphoribosyltransferase (EC 2.4.2.17)	Corynebacterium aurimucosum ATCC 700975 Gene: cauri_1254: ATP phosphoribosyltransferase (EC 2.4.2.17)	Corynebacterium diphtheriae NCTC 13129 Gene: DIP1256: ATP phosphoribosyltransferase (EC 2.4.2.17)	Corynebacterium efficiens YS-314 Gene: CE1634: ATP phosphoribosyltransferase (EC 2.4.2.17)	Corynebacterium glutamicum ATCC 13032 Gene: cg1698: ATP phosphoribosyltransferase (EC 2.4.2.17)	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385 Gene: ckrop_0916: ATP phosphoribosyltransferase (EC 2.4.2.17)	Corynebacterium urealyticum DSM 7109 Gene: cur_1035: ATP phosphoribosyltransferase (EC 2.4.2.17)	ATP phosphoribosyltransferase (EC 2.4.2.17)
aspA	Corynebacterium amycolatum SK46 Gene: CORAM0001_0991: Aspartate ammonia-lyase (EC 4.3.1.1)	Corynebacterium aurimucosum ATCC 700975 Gene: cauri_1255: Aspartate ammonia-lyase (EC 4.3.1.1)	Corynebacterium diphtheriae NCTC 13129 Gene: DIP1254: Aspartate ammonia-lyase (EC 4.3.1.1)	Corynebacterium efficiens YS-314 Gene: CE1633: Aspartate ammonia-lyase (EC 4.3.1.1)	Corynebacterium glutamicum ATCC 13032 Gene: cg1697: Aspartate ammonia-lyase (EC 4.3.1.1)	Corynebacterium jeikeium K411 Gene: jk0951: Aspartate ammonia-lyase (EC 4.3.1.1)	Corynebacterium kroppenstedtii DSM 44385 Gene: ckrop_1567: Aspartate ammonia-lyase (EC 4.3.1.1)	Corynebacterium urealyticum DSM 7109 Gene: cur_1036: Aspartate ammonia-lyase (EC 4.3.1.1)	Aspartate ammonia-lyase (EC 4.3.1.1)

CRON 7.
paaR	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	* Corynebacterium efficiens YS-314 Site: position = 38 score = 4.67642 sequence = ACTTACCGAATGGACGGTAGTA Site: position = -595 score = 5.17828 sequence = ACCGACCGCCCGGTCAGTATAT Site: position = -599 score = 6.20474 sequence = ACTAACCGACCGCCCGGTCAGT Gene: CE0665: Transcriptional regulator of phenylacetic acid degradation, TetR family	Corynebacterium glutamicum ATCC 13032	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Transcriptional regulator of phenylacetic acid degradation, TetR family

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog PaaR - Corynebacteriaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --