Regulog TPP - Chloroflexia

Properties
Regulator type:	RNA regulatory element
Name:	TPP
RFAM:	RF00059
Regulation mode:
Biological process:	Thiamine biosynthesis
Effector:	Thiamine pyrophosphate
Phylum:	Chloroflexi

Member of regulog collections

By taxonomy - Chloroflexi
By RNA motif - TPP
By effector - Thiamine pyrophosphate
By pathway - Thiamine biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Chloroflexus aggregans DSM 9485	7	2
Chloroflexus sp. Y-400-fl	11	4
Roseiflexus castenholzii DSM 13941	10	3
Roseiflexus sp. RS-1	14	4
Herpetosiphon aurantiacus ATCC 23779	1	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes						Function

CRON 1.
thiB	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1	* Herpetosiphon aurantiacus ATCC 23779 Site: position = -160 score = 78.25 sequence = ACAACCGCTAGGGGA... Gene: Haur_0261: Thiamin ABC transporter, substrate-binding component	Thiamin ABC transporter, substrate-binding component

CRON 2.
COG0011	* Chloroflexus aggregans DSM 9485 Site: position = -184 score = 70.23 sequence = TATGTAGCGAGGGGT... Gene: Cagg_3115: Cytoplasmic thiamin-binding component of thiamin ABC transporter, COG0011 family	* Chloroflexus sp. Y-400-fl Site: position = -197 score = 67.7 sequence = TACGCGCTGCCAGGG... Gene: Chy400_0456: Cytoplasmic thiamin-binding component of thiamin ABC transporter, COG0011 family	* Roseiflexus castenholzii DSM 13941 Site: position = -157 score = 58.1 sequence = AGGGGAGCCAGGTGA... Gene: Rcas_0665: Cytoplasmic thiamin-binding component of thiamin ABC transporter, COG0011 family	* Roseiflexus sp. RS-1 Site: position = -218 score = 59.61 sequence = AGGGGAGCCAGGAGA... Gene: RoseRS_0668: Cytoplasmic thiamin-binding component of thiamin ABC transporter, COG0011 family	Herpetosiphon aurantiacus ATCC 23779	Cytoplasmic thiamin-binding component of thiamin ABC transporter, COG0011 family
thiX	Chloroflexus aggregans DSM 9485 Gene: Cagg_3116: Hydroxymethylpyrimidine ABC transporter, transmembrane component	Chloroflexus sp. Y-400-fl Gene: Chy400_0455: Hydroxymethylpyrimidine ABC transporter, transmembrane component	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0666: Hydroxymethylpyrimidine ABC transporter, transmembrane component	Roseiflexus sp. RS-1 Gene: RoseRS_0669: Hydroxymethylpyrimidine ABC transporter, transmembrane component	Herpetosiphon aurantiacus ATCC 23779	Hydroxymethylpyrimidine ABC transporter, transmembrane component
thiY	Chloroflexus aggregans DSM 9485 Gene: Cagg_3117: Hydroxymethylpyrimidine ABC transporter, substrate-binding component	Chloroflexus sp. Y-400-fl Gene: Chy400_0454: Hydroxymethylpyrimidine ABC transporter, substrate-binding component	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0667: Hydroxymethylpyrimidine ABC transporter, substrate-binding component	Roseiflexus sp. RS-1 Gene: RoseRS_0670: Hydroxymethylpyrimidine ABC transporter, substrate-binding component	Herpetosiphon aurantiacus ATCC 23779	Hydroxymethylpyrimidine ABC transporter, substrate-binding component
thiZ	Chloroflexus aggregans DSM 9485 Gene: Cagg_3118: Hydroxymethylpyrimidine ABC transporter, ATPase component	Chloroflexus sp. Y-400-fl Gene: Chy400_0453: Hydroxymethylpyrimidine ABC transporter, ATPase component	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0668: Hydroxymethylpyrimidine ABC transporter, ATPase component	Roseiflexus sp. RS-1 Gene: RoseRS_0671: Hydroxymethylpyrimidine ABC transporter, ATPase component	Herpetosiphon aurantiacus ATCC 23779	Hydroxymethylpyrimidine ABC transporter, ATPase component

CRON 3.
thiE	Chloroflexus aggregans DSM 9485 Gene: Cagg_3166: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Chloroflexus sp. Y-400-fl Gene: Chy400_0400: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	* Roseiflexus castenholzii DSM 13941 Site: position = -180 score = 71.73 sequence = GGCGCCACTGGGGGA... Gene: Rcas_4121: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	* Roseiflexus sp. RS-1 Site: position = -183 score = 68.19 sequence = ACGGCGCCACTGGGG... Gene: RoseRS_1927: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_2443: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
thiM	* Chloroflexus aggregans DSM 9485 Site: position = -227 score = 64.76 sequence = ATAGATGCCAGGGGA... Gene: Cagg_3165: Hydroxyethylthiazole kinase (EC 2.7.1.50)	* Chloroflexus sp. Y-400-fl Site: position = -228 score = 61.84 sequence = ACTAATAAGCCAGGG... Gene: Chy400_0401: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_4122: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Roseiflexus sp. RS-1 Gene: RoseRS_1926: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_2444: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Hydroxyethylthiazole kinase (EC 2.7.1.50)
thiW	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl	Roseiflexus castenholzii DSM 13941 Gene: Rcas_4123: Substrate-specific component ThiW of predicted thiazole ECF transporter	Roseiflexus sp. RS-1 Gene: RoseRS_1925: Substrate-specific component ThiW of predicted thiazole ECF transporter	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_2442: Substrate-specific component ThiW of predicted thiazole ECF transporter	Substrate-specific component ThiW of predicted thiazole ECF transporter
ecfAA	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl Gene: Chy400_0858: Substrate-specific component ThiW of predicted thiazole ECF transporter/ ATPase component of general energizing module of ECF transporters / ATPase component of general energizing module of ECF transporters	Roseiflexus castenholzii DSM 13941 Gene: Rcas_4124: ATPase component of general energizing module of ECF transporters / ATPase component of general energizing module of ECF transporters	2 Roseiflexus sp. RS-1 Gene: RoseRS_1924: ATPase component of general energizing module of ECF transporters Gene: RoseRS_1923: ATPase component of general energizing module of ECF transporters	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_2441: ATPase component of general energizing module of ECF transporters / ATPase component of general energizing module of ECF transporters	ATPase component of general energizing module of ECF transporters / ATPase component of general energizing module of ECF transporters
ecfT	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl Gene: Chy400_0857: Transmembrane component of general energizing module of ECF transporters	Roseiflexus castenholzii DSM 13941 Gene: Rcas_4125: Transmembrane component of general energizing module of ECF transporters	Roseiflexus sp. RS-1 Gene: RoseRS_1922: Transmembrane component of general energizing module of ECF transporters	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_2440: Transmembrane component of general energizing module of ECF transporters	Transmembrane component of general energizing module of ECF transporters
thiD	Chloroflexus aggregans DSM 9485 Gene: Cagg_3167: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Chloroflexus sp. Y-400-fl Gene: Chy400_0399: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_4126: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Roseiflexus sp. RS-1 Gene: RoseRS_1921: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Herpetosiphon aurantiacus ATCC 23779 Gene: Haur_2438: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Phosphomethylpyrimidine kinase (EC 2.7.4.7)
cytX	Chloroflexus aggregans DSM 9485	* Chloroflexus sp. Y-400-fl Site: position = -202 score = 59.19 sequence = ACAGCGTGTATGAGG... Gene: Chy400_0859: Predicted hydroxymethylpyrimidine transporter CytX	Roseiflexus castenholzii DSM 13941	* Roseiflexus sp. RS-1 Site: position = -175 score = 73.77 sequence = TAAGCGTGTATGAGG... Gene: RoseRS_2771: Predicted hydroxymethylpyrimidine transporter CytX	Herpetosiphon aurantiacus ATCC 23779	Predicted hydroxymethylpyrimidine transporter CytX

CRON 4.
tenA	Chloroflexus aggregans DSM 9485	* Chloroflexus sp. Y-400-fl Site: position = -193 score = 56.17 sequence = GTGTTCCGTAGGGGC... Gene: Chy400_0862: Thiaminase II (EC 3.5.99.2)	* Roseiflexus castenholzii DSM 13941 Site: position = -241 score = 55.82 sequence = CAGTGTTCCGTAGGG... Gene: Rcas_1431: Thiaminase II (EC 3.5.99.2)	* Roseiflexus sp. RS-1 Site: position = -221 score = 60.4 sequence = TACCGTTCCGTAGGG... Gene: RoseRS_1028: Thiaminase II (EC 3.5.99.2)	Herpetosiphon aurantiacus ATCC 23779	Thiaminase II (EC 3.5.99.2)
Cagg_0487	Chloroflexus aggregans DSM 9485 Gene: Cagg_0487: hypothetical protein	Chloroflexus sp. Y-400-fl Gene: Chy400_2977: hypothetical protein	Roseiflexus castenholzii DSM 13941 Gene: Rcas_1430: hypothetical protein	Roseiflexus sp. RS-1 Gene: RoseRS_1027: hypothetical protein	Herpetosiphon aurantiacus ATCC 23779	hypothetical protein

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog TPP - Chloroflexia

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --