Regulog T-box(Trp) - Lactobacillaceae

Properties
Regulator type:	RNA regulatory element
Name:	T-box
RFAM:	RF00230
Regulation mode:
Biological process:	Amino acid metabolism
Effector:	Trp-tRNA
Phylum:	Firmicutes

Member of regulog collections

By taxonomy - Lactobacillaceae
By RNA motif - T-box
By effector - Trp-tRNA
By pathway - Amino acid metabolism

Statistics of regulated genes
Genome	Genes	Operons
Oenococcus oeni PSU-1
Lactobacillus reuteri JCM 1112	1	1
Lactobacillus helveticus DPC 4571
Lactobacillus fermentum IFO 3956	1	1
Lactobacillus salivarius subsp. salivarius UCC118	1	1
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
Lactobacillus acidophilus NCFM
Lactobacillus johnsonii NCC 533
Lactobacillus plantarum WCFS1	9	3
Lactobacillus casei ATCC 334	7	3
Lactobacillus brevis ATCC 367	2	2
Lactobacillus sakei subsp. sakei 23K	1	1
Pediococcus pentosaceus ATCC 25745	1	1
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	7	1
Lactobacillus rhamnosus GG	1	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
trpS	Oenococcus oeni PSU-1 Gene: OEOE_1800: Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2	* Lactobacillus reuteri JCM 1112 Site: position = -196 score = 37.18 sequence = TAAAATTAACTATAT... Gene: LAR_0194: Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2	Lactobacillus helveticus DPC 4571 Gene: lhv_0226: Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2	* Lactobacillus fermentum IFO 3956 Site: position = -218 score = 46.47 sequence = AATCAGACCGGGAAA... Gene: LAF_0067: Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2	* Lactobacillus salivarius subsp. salivarius UCC118 Site: position = -206 score = 65.5 sequence = AATCTTCGTTGAACA... Gene: LSL_0218: Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0293: Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2	Lactobacillus acidophilus NCFM Gene: LBA0209: Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2	Lactobacillus johnsonii NCC 533 Gene: LJ0198: Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2	* Lactobacillus plantarum WCFS1 Site: position = -246 score = 84.75 sequence = ATTAATCGTTGAAGA... Gene: lp_0434: Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2	* Lactobacillus casei ATCC 334 Site: position = -350 score = 72.79 sequence = TATTCACACAAACGA... Gene: LSEI_2624: Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2	* Lactobacillus brevis ATCC 367 Site: position = -223 score = 68.04 sequence = AGACTAACGATAAAA... Gene: LVIS_0448: Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2	* Lactobacillus sakei subsp. sakei 23K Site: position = -253 score = 86.18 sequence = AAACAGAGTGAAGGA... Gene: LSA0327: Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2	* Pediococcus pentosaceus ATCC 25745 Site: position = -215 score = 63.8 sequence = TTTAAAATGAAAGTA... Gene: PEPE_0256: Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1856: Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2	* Lactobacillus rhamnosus GG Site: position = -226 score = 73.58 sequence = TATTCATACAAACGA... Gene: LGG_02609: Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2	Tryptophanyl-tRNA synthetase (EC 6.1.1.2) ## type 2

CRON 2.
trpB	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_1657: Tryptophan synthase beta chain (EC 4.2.1.20)	Lactobacillus casei ATCC 334 Gene: LSEI_0075: Tryptophan synthase beta chain (EC 4.2.1.20)	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -327 score = 67.78 sequence = TCATAAACTGATGAG... Gene: LEUM_1176: Tryptophan synthase beta chain (EC 4.2.1.20)	Lactobacillus rhamnosus GG Gene: LGG_00099: Tryptophan synthase beta chain (EC 4.2.1.20)	Tryptophan synthase beta chain (EC 4.2.1.20)
trpD	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_1654: Anthranilate phosphoribosyltransferase (EC 2.4.2.18)	* Lactobacillus casei ATCC 334 Site: position = -468 score = 97.1 sequence = GAACAAACCGATGAT... Gene: LSEI_0078: Anthranilate phosphoribosyltransferase (EC 2.4.2.18)	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1175: Anthranilate phosphoribosyltransferase (EC 2.4.2.18)	Lactobacillus rhamnosus GG Gene: LGG_00102: Anthranilate phosphoribosyltransferase (EC 2.4.2.18)	Anthranilate phosphoribosyltransferase (EC 2.4.2.18)
trpC	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_1655: Indole-3-glycerol phosphate synthase (EC 4.1.1.48)	Lactobacillus casei ATCC 334 Gene: LSEI_0077: Indole-3-glycerol phosphate synthase (EC 4.1.1.48)	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1174: Indole-3-glycerol phosphate synthase (EC 4.1.1.48)	Lactobacillus rhamnosus GG Gene: LGG_00101: Indole-3-glycerol phosphate synthase (EC 4.1.1.48)	Indole-3-glycerol phosphate synthase (EC 4.1.1.48)
trpF	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_1656: Phosphoribosylanthranilate isomerase (EC 5.3.1.24)	Lactobacillus casei ATCC 334 Gene: LSEI_0076: Phosphoribosylanthranilate isomerase (EC 5.3.1.24)	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K Gene: LSA0255: Phosphoribosylanthranilate isomerase (EC 5.3.1.24)	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1173: Phosphoribosylanthranilate isomerase (EC 5.3.1.24)	Lactobacillus rhamnosus GG Gene: LGG_00100: Phosphoribosylanthranilate isomerase (EC 5.3.1.24)	Phosphoribosylanthranilate isomerase (EC 5.3.1.24)
trpA	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_1658: Tryptophan synthase alpha chain (EC 4.2.1.20)	Lactobacillus casei ATCC 334 Gene: LSEI_0074: Tryptophan synthase alpha chain (EC 4.2.1.20)	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1172: Tryptophan synthase alpha chain (EC 4.2.1.20)	Lactobacillus rhamnosus GG Gene: LGG_00098: Tryptophan synthase alpha chain (EC 4.2.1.20)	Tryptophan synthase alpha chain (EC 4.2.1.20)
trpE	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -372 score = 77.74 sequence = TGAAACCGATGAAGT... Gene: lp_1652: Anthranilate synthase, aminase component (EC 4.1.3.27) # TrpAa	Lactobacillus casei ATCC 334	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1171: Anthranilate synthase, aminase component (EC 4.1.3.27) # TrpAa	Lactobacillus rhamnosus GG	Anthranilate synthase, aminase component (EC 4.1.3.27) # TrpAa
trpG	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_1653: Anthranilate synthase, amidotransferase component (EC 4.1.3.27) # TrpAb	Lactobacillus casei ATCC 334	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1170: Anthranilate synthase, amidotransferase component (EC 4.1.3.27) # TrpAb	Lactobacillus rhamnosus GG	Anthranilate synthase, amidotransferase component (EC 4.1.3.27) # TrpAb

CRON 3.
oppA	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -396 score = 84.08 sequence = TTATAAACCAATGAG... Gene: lp_0092: Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)	* Lactobacillus casei ATCC 334 Site: position = -416 score = 89.92 sequence = ATGCAAACCTTTGAA... Gene: LSEI_2797: Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)	* Lactobacillus brevis ATCC 367 Site: position = -376 score = 99.66 sequence = AAACAAACCATTGAA... Gene: LVIS_0057: Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Lactobacillus rhamnosus GG Gene: LGG_02801: Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog T-box(Trp) - Lactobacillaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --