Regulog Lysine - Clostridiaceae
| Regulator type: | RNA regulatory element |
| Name: | Lysine |
| RFAM: | RF00168 |
| Regulation mode: | |
| Biological process: | Lysine biosynthesis |
| Effector: | Lysine |
| Phylum: | Firmicutes |
Member of regulog collections
- By taxonomy - Clostridiaceae
- By RNA motif - Lysine
- By effector - Lysine
- By pathway - Lysine biosynthesis
| Genome | Genes | Operons |
|---|---|---|
| Clostridium kluyveri DSM 555 | 3 | 2 |
| Clostridium sp. SS2/1 | ||
| Clostridium cellulolyticum H10 | 3 | 1 |
| Clostridium phytofermentans ISDg | 3 | 2 |
| Clostridium tetani E88 | 2 | 2 |
| Clostridium acetobutylicum ATCC 824 | 1 | 1 |
| Clostridium botulinum A str. ATCC 3502 | 4 | 3 |
| Clostridium novyi NT | 3 | 3 |
| Clostridium perfringens ATCC 13124 | 3 | 3 |
| Clostridium difficile 630 | 8 | 4 |
| Clostridium beijerincki NCIMB 8052 | 2 | 2 |
| Clostridium sp. OhILAs | 4 | 2 |
| Clostridium sp. L2-50 | 2 | 1 |
| Clostridium scindens ATCC 35704 | 1 | 1 |
| Clostridium nexile DSM 1787 | 1 | 1 |
| Clostridium leptum DSM 753 | 4 | 1 |
| Clostridium hiranonis DSM 13275 | 7 | 3 |
| Clostridium butyricum 5521 | 1 | 1 |
| Clostridium bolteae ATCC BAA-613 | 3 | 2 |
| Clostridium bartlettii DSM 16795 | 7 | 3 |
| Genes | Function | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CRON 1. | |||||||||||||||||||||
| lysC |
*
Clostridium kluyveri DSM 555 Site: position = -401 score = 97.22 sequence = CCTAGGGTAGAGGTG... Gene: CKL_0607: Aspartokinase (EC 2.7.2.4) |
Gene: CLOSS21_02234: Aspartokinase (EC 2.7.2.4) |
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Gene: null: Aspartokinase (EC 2.7.2.4) |
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Clostridium botulinum A str. ATCC 3502 Site: position = -332 score = 94.98 sequence = CTACTTATGGAGAGG... Gene: CBO3337: Aspartokinase (EC 2.7.2.4) |
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Clostridium difficile 630 Site: position = -251 score = 100.49 sequence = AGCCTAGGGTAGAGG... Gene: CD2054: Aspartokinase (EC 2.7.2.4) |
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Gene: CLOSCI_03696: Aspartokinase (EC 2.7.2.4) |
Gene: CLONEX_02746: Aspartokinase (EC 2.7.2.4) |
Gene: CLOLEP_02735: Aspartokinase (EC 2.7.2.4) |
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Clostridium hiranonis DSM 13275 Site: position = -300 score = 81.7 sequence = ACCAAGGTAGAGGCG... Gene: CLOHIR_01388: Aspartokinase (EC 2.7.2.4) |
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Gene: CLOBOL_02433: Aspartokinase (EC 2.7.2.4) |
*
Clostridium bartlettii DSM 16795 Site: position = -243 score = 86.18 sequence = AACCTAGGGTAGAGG... Gene: CLOBAR_01961: Aspartokinase (EC 2.7.2.4) |
Aspartokinase (EC 2.7.2.4) |
| lysA |
Gene: CKL_0608: Diaminopimelate decarboxylase (EC 4.1.1.20) |
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Gene: Ccel_2534: Diaminopimelate decarboxylase (EC 4.1.1.20) |
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*
Clostridium tetani E88 Site: position = -247 score = 93.78 sequence = TACCCAGGGTAGAGG... Gene: CTC02456: Diaminopimelate decarboxylase (EC 4.1.1.20) |
*
Clostridium acetobutylicum ATCC 824 Site: position = -279 score = 94.26 sequence = CCTTTTGTAGAGGTG... Gene: CAC0608: Diaminopimelate decarboxylase (EC 4.1.1.20) |
Gene: CBO3336: Diaminopimelate decarboxylase (EC 4.1.1.20) |
*
Clostridium novyi NT Site: position = -319 score = 100.31 sequence = CCTAAGGTAGAGGTG... Gene: NT01CX_1352: Diaminopimelate decarboxylase (EC 4.1.1.20) |
*
Clostridium perfringens ATCC 13124 Site: position = -302 score = 97.52 sequence = ACCAAAGTAGAGGTG... Gene: CPF_0576: Diaminopimelate decarboxylase (EC 4.1.1.20) |
Gene: CD2053: Diaminopimelate decarboxylase (EC 4.1.1.20) |
*
Clostridium beijerincki NCIMB 8052 Site: position = -487 score = 86.1 sequence = GACCTGGGGTAGAGG... Gene: Cbei_4787: Diaminopimelate decarboxylase (EC 4.1.1.20) |
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Gene: CLOLEP_02380: Diaminopimelate decarboxylase (EC 4.1.1.20) |
Gene: CLOHIR_01389: Diaminopimelate decarboxylase (EC 4.1.1.20) |
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Gene: CLOBAR_01960: Diaminopimelate decarboxylase (EC 4.1.1.20) |
Diaminopimelate decarboxylase (EC 4.1.1.20) |
| CRON 2. | |||||||||||||||||||||
| asd |
Gene: CKL_3207: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: CLOSS21_01903: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: Ccel_2591: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: null: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: CTC02293: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
2
Clostridium acetobutylicum ATCC 824 Gene: CAC0022: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) Gene: CAC0568: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: CBO3151: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: NT01CX_1747: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: CPF_2160: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
*
Clostridium difficile 630 Site: position = -346 score = 99.85 sequence = CCTAGGGTAGAGGTA... Gene: CD3224: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
2
Clostridium beijerincki NCIMB 8052 Gene: Cbei_1797: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) Gene: Cbei_0518: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: Clos_1162: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: CLOL250_02800: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: CLOSCI_01339: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: CLONEX_03027: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
*
Clostridium leptum DSM 753 Site: position = -320 score = 104.92 sequence = CCTAAGATAGAGGTG... Gene: CLOLEP_03139: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
*
Clostridium hiranonis DSM 13275 Site: position = -393 score = 88.93 sequence = TAACCTGCGTAGAGG... Gene: CLOHIR_00818: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: CBY_1203: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Gene: CLOBOL_02970: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
*
Clostridium bartlettii DSM 16795 Site: position = -341 score = 99.29 sequence = TAACCTAAGTAGAGG... Gene: CLOBAR_00365: Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
Aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) |
| dapA |
Gene: CKL_3206: Dihydrodipicolinate synthase (EC 4.2.1.52) |
Gene: CLOSS21_00345: Dihydrodipicolinate synthase (EC 4.2.1.52) |
*
Clostridium cellulolyticum H10 Site: position = -277 score = 112.12 sequence = TATGTAAGATAGAGG... Gene: Ccel_0526: Dihydrodipicolinate synthase (EC 4.2.1.52) |
*
Clostridium phytofermentans ISDg Site: position = -298 score = 108.23 sequence = AACAATTGGTAGAGG... Gene: null: Dihydrodipicolinate synthase (EC 4.2.1.52) |
Gene: CTC02294: Dihydrodipicolinate synthase (EC 4.2.1.52) |
Gene: CAC2378: Dihydrodipicolinate synthase (EC 4.2.1.52) |
Gene: CBO3152: Dihydrodipicolinate synthase (EC 4.2.1.52) |
Gene: NT01CX_1746: Dihydrodipicolinate synthase (EC 4.2.1.52) |
Gene: CPF_2161: Dihydrodipicolinate synthase (EC 4.2.1.52) |
2
Clostridium difficile 630 Gene: CD3223: Dihydrodipicolinate synthase (EC 4.2.1.52) Gene: CD3225: Dihydrodipicolinate synthase (EC 4.2.1.52) |
Gene: Cbei_1796: Dihydrodipicolinate synthase (EC 4.2.1.52) |
Gene: Clos_1163: Dihydrodipicolinate synthase (EC 4.2.1.52) |
*
Clostridium sp. L2-50 Site: position = -227 score = 104.67 sequence = AATTCAGTAGAGGCG... Gene: CLOL250_00644: Dihydrodipicolinate synthase (EC 4.2.1.52) |
Gene: CLOSCI_03684: Dihydrodipicolinate synthase (EC 4.2.1.52) |
Gene: CLONEX_02736: Dihydrodipicolinate synthase (EC 4.2.1.52) |
Gene: CLOLEP_03140: Dihydrodipicolinate synthase (EC 4.2.1.52) |
Gene: CLOHIR_00817: Dihydrodipicolinate synthase (EC 4.2.1.52) |
Gene: CBY_0567: Dihydrodipicolinate synthase (EC 4.2.1.52) |
*
Clostridium bolteae ATCC BAA-613 Site: position = -328 score = 98.04 sequence = ATCATAGAGTAGAGG... Gene: CLOBOL_04168: Dihydrodipicolinate synthase (EC 4.2.1.52) |
2
Clostridium bartlettii DSM 16795 Gene: CLOBAR_02458: Dihydrodipicolinate synthase (EC 4.2.1.52) Gene: CLOBAR_00364: Dihydrodipicolinate synthase (EC 4.2.1.52) |
Dihydrodipicolinate synthase (EC 4.2.1.52) |
| dapB |
2
Clostridium kluyveri DSM 555 Gene: CKL_3205: Dihydrodipicolinate reductase (EC 1.3.1.26) Gene: CKL_2799: Dihydrodipicolinate reductase (EC 1.3.1.26) |
Gene: CLOSS21_00346: Dihydrodipicolinate reductase (EC 1.3.1.26) |
2
Clostridium cellulolyticum H10 Gene: Ccel_0519: Dihydrodipicolinate reductase (EC 1.3.1.26) Gene: Ccel_0525: Dihydrodipicolinate reductase (EC 1.3.1.26) |
Gene: null: Dihydrodipicolinate reductase (EC 1.3.1.26) |
Gene: CTC02295: Dihydrodipicolinate reductase (EC 1.3.1.26) |
Gene: CAC2379: Dihydrodipicolinate reductase (EC 1.3.1.26) |
2
Clostridium botulinum A str. ATCC 3502 Gene: CBO3153: Dihydrodipicolinate reductase (EC 1.3.1.26) Gene: CBO0791: Dihydrodipicolinate reductase (EC 1.3.1.26) |
Gene: NT01CX_1745: Dihydrodipicolinate reductase (EC 1.3.1.26) |
Gene: CPF_2162: Dihydrodipicolinate reductase (EC 1.3.1.26) |
2
Clostridium difficile 630 Gene: CD3226: Dihydrodipicolinate reductase (EC 1.3.1.26) Gene: CD3229: Dihydrodipicolinate reductase (EC 1.3.1.26) |
2
Clostridium beijerincki NCIMB 8052 Gene: Cbei_1795: Dihydrodipicolinate reductase (EC 1.3.1.26) Gene: Cbei_2934: Dihydrodipicolinate reductase (EC 1.3.1.26) |
Gene: Clos_1164: Dihydrodipicolinate reductase (EC 1.3.1.26) |
Gene: CLOL250_00645: Dihydrodipicolinate reductase (EC 1.3.1.26) |
2
Clostridium scindens ATCC 35704 Gene: CLOSCI_03685: Dihydrodipicolinate reductase (EC 1.3.1.26) Gene: CLOSCI_00327: Dihydrodipicolinate reductase (EC 1.3.1.26) |
Gene: CLONEX_02737: Dihydrodipicolinate reductase (EC 1.3.1.26) |
Gene: CLOLEP_03141: Dihydrodipicolinate reductase (EC 1.3.1.26) |
2
Clostridium hiranonis DSM 13275 Gene: CLOHIR_00816: Dihydrodipicolinate reductase (EC 1.3.1.26) Gene: CLOHIR_00814: Dihydrodipicolinate reductase (EC 1.3.1.26) |
Gene: CBY_0568: Dihydrodipicolinate reductase (EC 1.3.1.26) |
Gene: CLOBOL_04167: Dihydrodipicolinate reductase (EC 1.3.1.26) |
Gene: CLOBAR_00363: Dihydrodipicolinate reductase (EC 1.3.1.26) |
Dihydrodipicolinate reductase (EC 1.3.1.26) |
| dapD |
Gene: CKL_3211: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) |
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Gene: CAC2381: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) |
Gene: CBO3156: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) |
Gene: NT01CX_1738: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) |
Gene: CPF_2165: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) |
Gene: CD3227: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) |
2
Clostridium beijerincki NCIMB 8052 Gene: Cbei_4881: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) Gene: Cbei_1791: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) |
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Gene: CLONEX_00178: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) |
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Gene: CLOHIR_00815: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) |
Gene: CBY_1863: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) |
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Gene: CLOBAR_00362: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) |
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase (EC 2.3.1.89) |
| lysC2 |
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Gene: Ccel_0524: Aspartokinase II ( EC:2.7.2.4 ) |
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Gene: CLOLEP_03142: Aspartokinase II ( EC:2.7.2.4 ) |
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Aspartokinase II ( EC:2.7.2.4 ) |
| CRON 3. | |||||||||||||||||||||
| Clos_0722 |
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*
Clostridium sp. OhILAs Site: position = -333 score = 108.64 sequence = GGTGGGGTAGAGGCG... Gene: Clos_0722: Amino acid ABC transporter, amino acid-binding protein |
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Gene: CLOBAR_00196: Amino acid ABC transporter, amino acid-binding protein |
Amino acid ABC transporter, amino acid-binding protein |
| Clos_0723 |
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Gene: Clos_0723: Amino acid ABC transporter, permease protein |
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Gene: CLOBAR_00197: Amino acid ABC transporter, permease protein |
Amino acid ABC transporter, permease protein |
| Clos_0724 |
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Gene: Clos_0724: Amino acid ABC transporter, ATP-binding protein |
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Gene: CLOBAR_00198: Amino acid ABC transporter, ATP-binding protein |
Amino acid ABC transporter, ATP-binding protein |
| CRON 4. | |||||||||||||||||||||
| lysP |
*
Clostridium kluyveri DSM 555 Site: position = -295 score = 105.95 sequence = TTTAAGATAGAGGTG... Gene: CKL_1545: Lysine-specific permease |
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2
Clostridium acetobutylicum ATCC 824 Gene: CAC3164: Lysine-specific permease Gene: CAC3347: Lysine-specific permease |
*
Clostridium botulinum A str. ATCC 3502 Site: position = -305 score = 112.44 sequence = ACTGAGGTAGAGGTG... Gene: CBO0250: Lysine-specific permease |
*
Clostridium novyi NT Site: position = -340 score = 110.52 sequence = TAACTAAGATAGAGG... Gene: NT01CX_2354: Lysine-specific permease |
*
Clostridium perfringens ATCC 13124 Site: position = -301 score = 117.81 sequence = TAACTGAGATAGAGG... Gene: CPF_1369: Lysine-specific permease |
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*
Clostridium beijerincki NCIMB 8052 Site: position = -327 score = 123.83 sequence = TAACTAAGATAGAGG... Gene: Cbei_0788: Lysine-specific permease |
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Lysine-specific permease |
| CRON 5. | |||||||||||||||||||||
| yvsH |
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*
Clostridium sp. OhILAs Site: position = -365 score = 106.87 sequence = CGGGTGGGGTAGAGG... Gene: Clos_0865: Amino acid permease |
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Gene: CLOBAR_00048: Amino acid permease |
Amino acid permease |
| CRON 6. | |||||||||||||||||||||
| COG1288 |
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*
Clostridium difficile 630 Site: position = -309 score = 111.91 sequence = AGATTGAGGTAGAGG... Gene: CD3100: C4-dicarboxylate anaerobic carrier-like |
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C4-dicarboxylate anaerobic carrier-like |
| CRON 7. | |||||||||||||||||||||
| alsT |
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*
Clostridium bolteae ATCC BAA-613 Site: position = -338 score = 79.92 sequence = AGGATGCGATAGAGG... Gene: CLOBOL_04690: Na+/alanine symporter family transporter |
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Na+/alanine symporter family transporter |
| CRON 8. | |||||||||||||||||||||
| lysW |
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Gene: CLOSS21_01929: Predicted lysine transporter, NhaC family |
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*
Clostridium phytofermentans ISDg Site: position = -312 score = 100.12 sequence = ACATTGATAGAGGTG... Gene: null: Predicted lysine transporter, NhaC family |
*
Clostridium tetani E88 Site: position = -318 score = 106.39 sequence = AGAAAGGTAGAGGCG... Gene: CTC00567: Predicted lysine transporter, NhaC family |
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*
Clostridium botulinum A str. ATCC 3502 Site: position = -334 score = 123.03 sequence = AAGTAGATAGAGGTG... Gene: CBO0421: Predicted lysine transporter, NhaC family |
*
Clostridium novyi NT Site: position = -307 score = 116.36 sequence = GTTTAGTGATAGAGG... Gene: NT01CX_0133: Predicted lysine transporter, NhaC family |
*
Clostridium perfringens ATCC 13124 Site: position = -335 score = 110.57 sequence = AAAAAGAGGTAGAGG... Gene: CPF_2850: Predicted lysine transporter, NhaC family |
*
Clostridium difficile 630 Site: position = -319 score = 101.75 sequence = AGAAGGGTAGAGGCG... Gene: CD1655: Predicted lysine transporter, NhaC family |
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Gene: CLOL250_01927: Predicted lysine transporter, NhaC family |
*
Clostridium scindens ATCC 35704 Site: position = -204 score = 78.15 sequence = TGGACTTGATAGAGG... Gene: CLOSCI_01581: Predicted lysine transporter, NhaC family |
*
Clostridium nexile DSM 1787 Site: position = -368 score = 108.1 sequence = CTAAAAGGATAGAGG... Gene: CLONEX_03655: Predicted lysine transporter, NhaC family |
Gene: CLOLEP_01079: Predicted lysine transporter, NhaC family |
*
Clostridium hiranonis DSM 13275 Site: position = -275 score = 94.34 sequence = TAAATGATAGAGGCG... Gene: CLOHIR_01339: Predicted lysine transporter, NhaC family |
*
Clostridium butyricum 5521 Site: position = -425 score = 117.54 sequence = CGAAAGAGGTAGAGG... Gene: CBY_2257: Predicted lysine transporter, NhaC family |
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*
Clostridium bartlettii DSM 16795 Site: position = -263 score = 97.44 sequence = AGTAAGGTAGAGGTG... Gene: CLOBAR_01794: Predicted lysine transporter, NhaC family |
Predicted lysine transporter, NhaC family |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |