Regulog NtrC - Burkholderia

Properties
Regulator type:	Transcription factor
Regulator family:	Fis
Regulation mode:	activator (repressor)
Biological process:	Nitrogen assimilation
Effector:	Phosphorylated NtrB, signal histidine kinase
Phylum:	Proteobacteria/beta
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 27 sites [see more]

Member of regulog collections

By taxonomy - Burkholderia
By trascription factor - NtrC
By TF family - Fis
By effector - Phosphorylated NtrB, signal histidine kinase
By pathway - Nitrogen assimilation

Statistics of regulated genes
Genome	Genes	Operons
Burkholderia pseudomallei K96243	7	2
Burkholderia mallei ATCC 23344	8	2
Burkholderia sp. 383	8	3
Burkholderia cepacia AMMD	8	3
Burkholderia vietnamiensis G4	8	3
Burkholderia glumae BGR1	7	2
Burkholderia xenovorans LB400	6	2
Burkholderia phymatum STM815	7	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
glnA	* Burkholderia pseudomallei K96243 Site: position = -312 score = 4.73355 sequence = CGCACTAAAGCGGTGCA Site: position = -283 score = 5.00357 sequence = AGCACCAAATTGGTGTT Gene: BPSL2318: Glutamine synthetase type I (EC 6.3.1.2)	* Burkholderia mallei ATCC 23344 Site: position = -312 score = 4.73355 sequence = CGCACTAAAGCGGTGCA Site: position = -283 score = 4.947 sequence = AGCACCAAATTAGTGTT Gene: BMA1743: Glutamine synthetase type I (EC 6.3.1.2)	* Burkholderia sp. 383 Site: position = -242 score = 4.20337 sequence = TGCACCAGCGCGGTGCC Gene: Bcep18194_A5458: Glutamine synthetase type I (EC 6.3.1.2)	* Burkholderia cepacia AMMD Site: position = -242 score = 5.14942 sequence = TGCACCATTTCAGTGCG Gene: Bamb_2186: Glutamine synthetase type I (EC 6.3.1.2)	* Burkholderia vietnamiensis G4 Site: position = -282 score = 4.83297 sequence = TGCACCGAATCGGCGCT Gene: Bcep1808_2228: Glutamine synthetase type I (EC 6.3.1.2)	* Burkholderia glumae BGR1 Site: position = -275 score = 4.79019 sequence = CGCATTGATTTGGTGCG Site: position = -315 score = 4.59026 sequence = ATCACCAAAATGGTGCG Gene: bglu_1g25000: Glutamine synthetase type I (EC 6.3.1.2)	* Burkholderia xenovorans LB400 Site: position = -266 score = 4.86085 sequence = TGCACAAATCTGGTGCG Gene: Bxe_A1522: Glutamine synthetase type I (EC 6.3.1.2)	* Burkholderia phymatum STM815 Site: position = -273 score = 4.39007 sequence = TGCCCTGTGATGGTGCA Gene: Bphy_1481: Glutamine synthetase type I (EC 6.3.1.2)	Glutamine synthetase type I (EC 6.3.1.2)
ISBma2	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344 Gene: BMA1742: Transposase, IS4	Burkholderia sp. 383	Burkholderia cepacia AMMD	Burkholderia vietnamiensis G4	Burkholderia glumae BGR1	Burkholderia xenovorans LB400	Burkholderia phymatum STM815	Transposase, IS4
ntrB	Burkholderia pseudomallei K96243 Gene: BPSL2317: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Burkholderia mallei ATCC 23344 Gene: BMA1741: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Burkholderia sp. 383 Gene: Bcep18194_A5457: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Burkholderia cepacia AMMD Gene: Bamb_2185: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Burkholderia vietnamiensis G4 Gene: Bcep1808_2227: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Burkholderia glumae BGR1 Gene: bglu_1g24990: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Burkholderia xenovorans LB400 Gene: Bxe_A1523: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Burkholderia phymatum STM815 Gene: Bphy_1480: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Nitrogen regulation protein NR(II) (EC 2.7.3.-)
ntrC	Burkholderia pseudomallei K96243 Gene: BPSL2316: Nitrogen regulation protein NR(I), Fis family	Burkholderia mallei ATCC 23344 Gene: BMA1740: Nitrogen regulation protein NR(I), Fis family	Burkholderia sp. 383 Gene: Bcep18194_A5456: Nitrogen regulation protein NR(I), Fis family	Burkholderia cepacia AMMD Gene: Bamb_2184: Nitrogen regulation protein NR(I), Fis family	Burkholderia vietnamiensis G4 Gene: Bcep1808_2226: Nitrogen regulation protein NR(I), Fis family	Burkholderia glumae BGR1 Gene: bglu_1g24980: Nitrogen regulation protein NR(I), Fis family	Burkholderia xenovorans LB400 Gene: Bxe_A1524: Nitrogen regulation protein NR(I), Fis family	Burkholderia phymatum STM815 Gene: Bphy_1479: Nitrogen regulation protein NR(I), Fis family	Nitrogen regulation protein NR(I), Fis family

CRON 2.
narK	* Burkholderia pseudomallei K96243 Site: position = -294 score = 4.03128 sequence = CGCACGCACACAGTGCT Site: position = -273 score = 5.23909 sequence = CGCACCAGATCAGTGCT Gene: BPSS1244: Nitrate/nitrite antiporter	* Burkholderia mallei ATCC 23344 Site: position = -273 score = 5.23909 sequence = CGCACCAGATCAGTGCT Site: position = -294 score = 4.03128 sequence = CGCACGCACACAGTGCT Gene: BMAA1087: Nitrate/nitrite antiporter	* Burkholderia sp. 383 Site: position = -305 score = 4.48357 sequence = CGCACGGGGACAGTGCT Site: position = -284 score = 4.06085 sequence = CGCACCACATCTGTGCC Gene: Bcep18194_B1343: Nitrate/nitrite antiporter	* Burkholderia cepacia AMMD Site: position = -288 score = 4.06085 sequence = CGCACCACATCTGTGCC Site: position = -309 score = 4.01772 sequence = CGCACGGCGACAGTGCT Gene: Bamb_3937: Nitrate/nitrite antiporter	* Burkholderia vietnamiensis G4 Site: position = -303 score = 4.04395 sequence = CGCACGGCGATAGTGCT Site: position = -282 score = 4.06085 sequence = CGCACCACATCTGTGCC Gene: Bcep1808_5046: Nitrate/nitrite antiporter	* Burkholderia glumae BGR1 Site: position = -296 score = 4.10749 sequence = CGCACGCGCTTAGTGCT Gene: bglu_2g10010: Nitrate/nitrite antiporter	Burkholderia xenovorans LB400	* Burkholderia phymatum STM815 Site: position = -272 score = 4.61265 sequence = TGCACCAGCCCAGTGCC Gene: Bphy_5658: Nitrate/nitrite antiporter	Nitrate/nitrite antiporter
nasD	Burkholderia pseudomallei K96243 Gene: BPSS1243: Nitrite reductase, large subunit (EC 1.7.1.4)	Burkholderia mallei ATCC 23344 Gene: BMAA1086: Nitrite reductase, large subunit (EC 1.7.1.4)	Burkholderia sp. 383 Gene: Bcep18194_B1344: Nitrite reductase, large subunit (EC 1.7.1.4)	Burkholderia cepacia AMMD Gene: Bamb_3936: Nitrite reductase, large subunit (EC 1.7.1.4)	Burkholderia vietnamiensis G4 Gene: Bcep1808_5045: Nitrite reductase, large subunit (EC 1.7.1.4)	Burkholderia glumae BGR1 Gene: bglu_2g10020: Nitrite reductase, large subunit (EC 1.7.1.4)	* Burkholderia xenovorans LB400 Site: position = -284 score = 4.01332 sequence = CGCACCATGCGTGTGCT Gene: Bxe_A2214: Nitrite reductase, large subunit (EC 1.7.1.4)	Burkholderia phymatum STM815 Gene: Bphy_5659: Nitrite reductase, large subunit (EC 1.7.1.4)	Nitrite reductase, large subunit (EC 1.7.1.4)
nasE	Burkholderia pseudomallei K96243 Gene: BPSS1242: Nitrite reductase, small subunit (EC 1.7.1.4)	Burkholderia mallei ATCC 23344 Gene: BMAA1085: Nitrite reductase, small subunit (EC 1.7.1.4)	Burkholderia sp. 383 Gene: Bcep18194_B1345: Nitrite reductase, small subunit (EC 1.7.1.4)	Burkholderia cepacia AMMD Gene: Bamb_3935: Nitrite reductase, small subunit (EC 1.7.1.4)	Burkholderia vietnamiensis G4 Gene: Bcep1808_5044: Nitrite reductase, small subunit (EC 1.7.1.4)	Burkholderia glumae BGR1 Gene: bglu_2g10030: Nitrite reductase, small subunit (EC 1.7.1.4)	Burkholderia xenovorans LB400 Gene: Bxe_A2213: Nitrite reductase, small subunit (EC 1.7.1.4)	Burkholderia phymatum STM815 Gene: Bphy_5660: Nitrite reductase, small subunit (EC 1.7.1.4)	Nitrite reductase, small subunit (EC 1.7.1.4)
nasBA	Burkholderia pseudomallei K96243 Gene: BPSS1241: Assimilatory nitrate reductase, large and small subunits protein fusion (EC:1.7.99.4)	Burkholderia mallei ATCC 23344 Gene: BMAA1084: Assimilatory nitrate reductase, large and small subunits protein fusion (EC:1.7.99.4)	Burkholderia sp. 383 Gene: Bcep18194_B1346: Assimilatory nitrate reductase, large and small subunits protein fusion (EC:1.7.99.4)	Burkholderia cepacia AMMD Gene: Bamb_3934: Assimilatory nitrate reductase, large and small subunits protein fusion (EC:1.7.99.4)	Burkholderia vietnamiensis G4 Gene: Bcep1808_5043: Assimilatory nitrate reductase, large and small subunits protein fusion (EC:1.7.99.4)	Burkholderia glumae BGR1 Gene: bglu_2g10040: Assimilatory nitrate reductase, large and small subunits protein fusion (EC:1.7.99.4)	Burkholderia xenovorans LB400 Gene: Bxe_A2212: Assimilatory nitrate reductase, large and small subunits protein fusion (EC:1.7.99.4)	Burkholderia phymatum STM815 Gene: Bphy_5661: Assimilatory nitrate reductase, large and small subunits protein fusion (EC:1.7.99.4)	Assimilatory nitrate reductase, large and small subunits protein fusion (EC:1.7.99.4)

CRON 3.
amtB	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	* Burkholderia sp. 383 Site: position = -274 score = 4.58351 sequence = CGCGCCGGAACGGTGCG Gene: Bcep18194_A4310: Ammonia permease	* Burkholderia cepacia AMMD Site: position = -255 score = 4.63886 sequence = CGCGCCAGACCGGTGCA Gene: Bamb_1085: Ammonia permease	* Burkholderia vietnamiensis G4 Site: position = -253 score = 4.63886 sequence = CGCACCAGACCGGCGCA Gene: Bcep1808_1116: Ammonia permease	Burkholderia glumae BGR1 Gene: bglu_1g10270: Ammonia permease	Burkholderia xenovorans LB400 Gene: Bxe_A2869: Ammonia permease	Burkholderia phymatum STM815 Gene: Bphy_1761: Ammonia permease	Ammonia permease

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog NtrC - Burkholderia

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --