Regulog IscR - Burkholderia

Properties
Regulator type:	Transcription factor
Regulator family:	Rrf2
Regulation mode:	activator (repressor)
Biological process:	Iron-sulfur cluster biogenesis
Effector:	Iron-sulfur cluster redox state
Phylum:	Proteobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 16 sites [see more]

Member of regulog collections

By taxonomy - Burkholderia
By trascription factor - IscR
By TF family - Rrf2
By effector - Iron-sulfur cluster redox state
By pathway - Iron-sulfur cluster biogenesis

Statistics of regulated genes
Genome	Genes	Operons
Burkholderia pseudomallei K96243	8	1
Burkholderia mallei ATCC 23344	8	1
Burkholderia sp. 383	8	1
Burkholderia cepacia AMMD	8	1
Burkholderia vietnamiensis G4	8	1
Burkholderia glumae BGR1	8	1
Burkholderia xenovorans LB400	8	1
Burkholderia phymatum STM815	8	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
iscR	* Burkholderia pseudomallei K96243 Site: position = -69 score = 7.46253 sequence = ATACTTGACTAAATTGGTCAAATAT Site: position = -42 score = 7.79991 sequence = ATACTTGACCAAAATCGTCAAGATT Gene: BPSL2290: Iron-sulfur cluster regulator IscR	* Burkholderia mallei ATCC 23344 Site: position = -69 score = 7.46253 sequence = ATACTTGACTAAATTGGTCAAATAT Site: position = -42 score = 7.70824 sequence = ATACTTGACAAAAATCGTCAAGATT Gene: BMA1709: Iron-sulfur cluster regulator IscR	* Burkholderia sp. 383 Site: position = -69 score = 7.80515 sequence = ATACTTGACTAAAATCGTCAAATAT Site: position = -42 score = 7.79991 sequence = ATACTTGACCAAAATCGTCAAGATT Gene: Bcep18194_A5433: Iron-sulfur cluster regulator IscR	* Burkholderia cepacia AMMD Site: position = -42 score = 7.79991 sequence = ATACTTGACCAAAATCGTCAAGATT Site: position = -69 score = 7.80515 sequence = ATACTTGACTAAAATCGTCAAATAT Gene: Bamb_2164: Iron-sulfur cluster regulator IscR	* Burkholderia vietnamiensis G4 Site: position = -42 score = 7.79991 sequence = ATACTTGACCAAAATCGTCAAGATT Site: position = -69 score = 7.51728 sequence = ATACTTGACTAAAAACGTCAAATAT Gene: Bcep1808_2206: Iron-sulfur cluster regulator IscR	* Burkholderia glumae BGR1 Site: position = -68 score = 6.87077 sequence = ATACTTGACTAAAAATGTCAGATAT Site: position = -41 score = 7.79991 sequence = ATACTTGACCAAAATCGTCAAGATT Gene: bglu_1g24710: Iron-sulfur cluster regulator IscR	* Burkholderia xenovorans LB400 Site: position = -68 score = 6.95083 sequence = ATACTTGACTAAATCGGTCATGTAT Site: position = -41 score = 7.2371 sequence = ATACTTGACAAAACTTGTCGAGAAT Gene: Bxe_A1552: Iron-sulfur cluster regulator IscR	* Burkholderia phymatum STM815 Site: position = -42 score = 7.32877 sequence = ATACTTGACCAAACTTGTCGAGAAT Site: position = -69 score = 7.12214 sequence = ATACTTGACTAAATCCGTCATGTAT Gene: Bphy_1459: Iron-sulfur cluster regulator IscR	Iron-sulfur cluster regulator IscR
iscS	Burkholderia pseudomallei K96243 Gene: BPSL2289: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Burkholderia mallei ATCC 23344 Gene: BMA1708: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Burkholderia sp. 383 Gene: Bcep18194_A5432: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Burkholderia cepacia AMMD Gene: Bamb_2163: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Burkholderia vietnamiensis G4 Gene: Bcep1808_2205: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Burkholderia glumae BGR1 Gene: bglu_1g24700: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Burkholderia xenovorans LB400 Gene: Bxe_A1553: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Burkholderia phymatum STM815 Gene: Bphy_1458: Cysteine desulfurase (EC 2.8.1.7), IscS subfamily	Cysteine desulfurase (EC 2.8.1.7), IscS subfamily
iscU	Burkholderia pseudomallei K96243 Gene: BPSL2288: Iron-sulfur cluster assembly scaffold protein IscU	Burkholderia mallei ATCC 23344 Gene: BMA1707: Iron-sulfur cluster assembly scaffold protein IscU	Burkholderia sp. 383 Gene: Bcep18194_A5431: Iron-sulfur cluster assembly scaffold protein IscU	Burkholderia cepacia AMMD Gene: Bamb_2162: Iron-sulfur cluster assembly scaffold protein IscU	Burkholderia vietnamiensis G4 Gene: Bcep1808_2204: Iron-sulfur cluster assembly scaffold protein IscU	Burkholderia glumae BGR1 Gene: bglu_1g24690: Iron-sulfur cluster assembly scaffold protein IscU	Burkholderia xenovorans LB400 Gene: Bxe_A1554: Iron-sulfur cluster assembly scaffold protein IscU	Burkholderia phymatum STM815 Gene: Bphy_1457: Iron-sulfur cluster assembly scaffold protein IscU	Iron-sulfur cluster assembly scaffold protein IscU
iscA	Burkholderia pseudomallei K96243 Gene: BPSL2287: Iron binding protein IscA for iron-sulfur cluster assembly	Burkholderia mallei ATCC 23344 Gene: BMA1706: Iron binding protein IscA for iron-sulfur cluster assembly	Burkholderia sp. 383 Gene: Bcep18194_A5430: Iron binding protein IscA for iron-sulfur cluster assembly	Burkholderia cepacia AMMD Gene: Bamb_2161: Iron binding protein IscA for iron-sulfur cluster assembly	Burkholderia vietnamiensis G4 Gene: Bcep1808_2203: Iron binding protein IscA for iron-sulfur cluster assembly	Burkholderia glumae BGR1 Gene: bglu_1g24680: Iron binding protein IscA for iron-sulfur cluster assembly	Burkholderia xenovorans LB400 Gene: Bxe_A1555: Iron binding protein IscA for iron-sulfur cluster assembly	Burkholderia phymatum STM815 Gene: Bphy_1456: Iron binding protein IscA for iron-sulfur cluster assembly	Iron binding protein IscA for iron-sulfur cluster assembly
hscB	Burkholderia pseudomallei K96243 Gene: BPSL2286: Chaperone protein HscB	Burkholderia mallei ATCC 23344 Gene: BMA1705: Chaperone protein HscB	Burkholderia sp. 383 Gene: Bcep18194_A5429: Chaperone protein HscB	Burkholderia cepacia AMMD Gene: Bamb_2160: Chaperone protein HscB	Burkholderia vietnamiensis G4 Gene: Bcep1808_2202: Chaperone protein HscB	Burkholderia glumae BGR1 Gene: bglu_1g24670: Chaperone protein HscB	Burkholderia xenovorans LB400 Gene: Bxe_A1556: Chaperone protein HscB	Burkholderia phymatum STM815 Gene: Bphy_1455: Chaperone protein HscB	Chaperone protein HscB
hscA	Burkholderia pseudomallei K96243 Gene: BPSL2285: Chaperone protein HscA	Burkholderia mallei ATCC 23344 Gene: BMA1704: Chaperone protein HscA	Burkholderia sp. 383 Gene: Bcep18194_A5428: Chaperone protein HscA	Burkholderia cepacia AMMD Gene: Bamb_2159: Chaperone protein HscA	Burkholderia vietnamiensis G4 Gene: Bcep1808_2201: Chaperone protein HscA	Burkholderia glumae BGR1 Gene: bglu_1g24660: Chaperone protein HscA	Burkholderia xenovorans LB400 Gene: Bxe_A1557: Chaperone protein HscA	Burkholderia phymatum STM815 Gene: Bphy_1454: Chaperone protein HscA	Chaperone protein HscA
fdx	Burkholderia pseudomallei K96243 Gene: BPSL2284: Ferredoxin, 2Fe-2S type, ISC system	Burkholderia mallei ATCC 23344 Gene: BMA1703: Ferredoxin, 2Fe-2S type, ISC system	Burkholderia sp. 383 Gene: Bcep18194_A5427: Ferredoxin, 2Fe-2S type, ISC system	Burkholderia cepacia AMMD Gene: Bamb_2158: Ferredoxin, 2Fe-2S type, ISC system	Burkholderia vietnamiensis G4 Gene: Bcep1808_2200: Ferredoxin, 2Fe-2S type, ISC system	Burkholderia glumae BGR1 Gene: bglu_1g24650: Ferredoxin, 2Fe-2S type, ISC system	Burkholderia xenovorans LB400 Gene: Bxe_A1558: Ferredoxin, 2Fe-2S type, ISC system	Burkholderia phymatum STM815 Gene: Bphy_1453: Ferredoxin, 2Fe-2S type, ISC system	Ferredoxin, 2Fe-2S type, ISC system
yfhJ	Burkholderia pseudomallei K96243 Gene: BPSL2283: putative Fe-S cluster assembly protein	Burkholderia mallei ATCC 23344 Gene: BMA1702: putative Fe-S cluster assembly protein	Burkholderia sp. 383 Gene: Bcep18194_A5426: putative Fe-S cluster assembly protein	Burkholderia cepacia AMMD Gene: Bamb_2157: putative Fe-S cluster assembly protein	Burkholderia vietnamiensis G4 Gene: Bcep1808_2199: putative Fe-S cluster assembly protein	Burkholderia glumae BGR1 Gene: bglu_1g24640: putative Fe-S cluster assembly protein	Burkholderia xenovorans LB400 Gene: Bxe_A1559: putative Fe-S cluster assembly protein	Burkholderia phymatum STM815 Gene: Bphy_1452: putative Fe-S cluster assembly protein	putative Fe-S cluster assembly protein

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog IscR - Burkholderia

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --