Regulog Cobalamin - Enterobacteriales
| Regulator type: | RNA regulatory element |
| Name: | Cobalamin |
| RFAM: | RF00174 |
| Regulation mode: | |
| Biological process: | Cobalamin biosynthesis |
| Effector: | Adenosylcobalamin |
| Phylum: | Proteobacteria |
Member of regulog collections
- By taxonomy - Enterobacteriales
- By RNA motif - Cobalamin
- By effector - Adenosylcobalamin
- By pathway - Cobalamin biosynthesis
| Genome | Genes | Operons |
|---|---|---|
| Escherichia coli str. K-12 substr. MG1655 | 2 | 1 |
| Salmonella typhimurium LT2 | 22 | 2 |
| Citrobacter koseri ATCC BAA-895 | 10 | 3 |
| Klebsiella pneumoniae subsp. pneumoniae MGH 78578 | 21 | 2 |
| Enterobacter sp. 638 | 2 | 1 |
| Erwinia amylovora ATCC 49946 | ||
| Yersinia pestis KIM | 2 | 1 |
| Serratia proteamaculans 568 | 2 | 1 |
| Erwinia carotovora subsp. atroseptica SCRI1043 | 2 | 1 |
| Edwardsiella tarda EIB202 | 19 | 2 |
| Proteus mirabilis HI4320 | 2 | 1 |
| Photorhabdus luminescens subsp. laumondii TTO1 | 15 | 1 |
| Genes | Function | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CRON 1. | |||||||||||||
| btuB |
*
Escherichia coli str. K-12 substr. MG1655 Site: position = -254 score = 86.04 sequence = TGTAGCATCCACTTG... Gene: b3966: Outer membrane vitamin B12 receptor BtuB |
*
Salmonella typhimurium LT2 Site: position = -258 score = 80.97 sequence = GGTAGCATCCGTGGG... Gene: STM4130: Outer membrane vitamin B12 receptor BtuB |
*
Citrobacter koseri ATCC BAA-895 Site: position = -256 score = 87.58 sequence = AATGTAGCATCCGTG... Gene: CKO_03025: Outer membrane vitamin B12 receptor BtuB |
*
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -251 score = 84.16 sequence = TGTAGCATTCGCCTA... Gene: KPN_04255: Outer membrane vitamin B12 receptor BtuB |
*
Enterobacter sp. 638 Site: position = -243 score = 87.97 sequence = ATTGTAGCATTCTGT... Gene: Ent638_4020: Outer membrane vitamin B12 receptor BtuB |
|
*
Yersinia pestis KIM Site: position = -330 score = 83.72 sequence = TCGTAGCATTGTGGT... Gene: y0325: Outer membrane vitamin B12 receptor BtuB |
*
Serratia proteamaculans 568 Site: position = -282 score = 92.88 sequence = GATCGTAGCATTGTC... Gene: Spro_4770: Outer membrane vitamin B12 receptor BtuB |
*
Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -368 score = 72.22 sequence = GATTGTAGGATGAGC... Gene: ECA4238: Outer membrane vitamin B12 receptor BtuB |
Gene: ETAE_3467: Outer membrane vitamin B12 receptor BtuB |
*
Proteus mirabilis HI4320 Site: position = -271 score = 96.87 sequence = TCGTAGCATAGCGAT... Gene: PMI3246: Outer membrane vitamin B12 receptor BtuB |
Gene: plu4735: Outer membrane vitamin B12 receptor BtuB |
Outer membrane vitamin B12 receptor BtuB |
| murI |
Gene: b3967: Glutamate racemase (EC 5.1.1.3) |
Gene: STM4131: Glutamate racemase (EC 5.1.1.3) |
Gene: CKO_03024: Glutamate racemase (EC 5.1.1.3) |
Gene: KPN_04256: Glutamate racemase (EC 5.1.1.3) |
Gene: Ent638_4019: Glutamate racemase (EC 5.1.1.3) |
|
Gene: y0326: Glutamate racemase (EC 5.1.1.3) |
Gene: Spro_4769: Glutamate racemase (EC 5.1.1.3) |
Gene: ECA4237: Glutamate racemase (EC 5.1.1.3) |
Gene: ETAE_3466: Glutamate racemase (EC 5.1.1.3) |
Gene: PMI3247: Glutamate racemase (EC 5.1.1.3) |
Gene: plu4734: Glutamate racemase (EC 5.1.1.3) |
Glutamate racemase (EC 5.1.1.3) |
| CRON 2. | |||||||||||||
| cbiA |
|
*
Salmonella typhimurium LT2 Site: position = -273 score = 100.98 sequence = GCCATAACGTAAACC... Gene: STM2035: Cobyrinic acid A,C-diamide synthase |
*
Citrobacter koseri ATCC BAA-895 Site: position = -272 score = 98.19 sequence = CATAACATCAGCCGA... Gene: CKO_00802: Cobyrinic acid A,C-diamide synthase |
*
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -194 score = 91.09 sequence = TCGGCGAAACAAACC... Gene: KPN_03200: Cobyrinic acid A,C-diamide synthase |
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*
Edwardsiella tarda EIB202 Site: position = -273 score = 93.69 sequence = ACCATGTAATAAGCC... Gene: ETAE_2004: Cobyrinic acid A,C-diamide synthase |
|
*
Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -289 score = 92.92 sequence = CGGGTATAAACCGCC... Gene: plu2999: Cobyrinic acid A,C-diamide synthase |
Cobyrinic acid A,C-diamide synthase |
| cbiB |
|
Gene: STM2034: Adenosylcobinamide-phosphate synthase |
Gene: CKO_00804: Adenosylcobinamide-phosphate synthase |
Gene: KPN_03199: Adenosylcobinamide-phosphate synthase |
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Gene: ETAE_2003: Adenosylcobinamide-phosphate synthase |
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Gene: plu2998: Adenosylcobinamide-phosphate synthase |
Adenosylcobinamide-phosphate synthase |
| cbiC |
|
Gene: STM2033: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) |
Gene: CKO_00805: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) |
Gene: KPN_03198: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) |
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Gene: ETAE_2002: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) |
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Gene: plu2997: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) |
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) |
| cbiD |
|
Gene: STM2032: Cobalt-precorrin-6 synthase, anaerobic |
Gene: CKO_00806: Cobalt-precorrin-6 synthase, anaerobic |
Gene: KPN_03197: Cobalt-precorrin-6 synthase, anaerobic |
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Gene: ETAE_2001: Cobalt-precorrin-6 synthase, anaerobic |
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Gene: plu2996: Cobalt-precorrin-6 synthase, anaerobic |
Cobalt-precorrin-6 synthase, anaerobic |
| cbiE |
|
Gene: STM2031: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) |
Gene: CKO_00807: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) |
Gene: KPN_03196: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) |
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Gene: ETAE_2000: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) |
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Gene: plu2995: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) |
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) |
| cbiT |
|
Gene: STM2030: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) |
Gene: CKO_00808: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) |
Gene: KPN_03195: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) |
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Gene: ETAE_1999: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) |
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Gene: plu2994: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) |
Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) |
| cbiF |
|
Gene: STM2029: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) |
Gene: CKO_00809: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) |
Gene: KPN_03194: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) |
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Gene: ETAE_1998: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) |
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Gene: plu2993: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) |
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) |
| cbiG |
|
Gene: STM2028: Cobalamin biosynthesis protein CbiG |
Gene: CKO_00810: Cobalamin biosynthesis protein CbiG |
Gene: KPN_03193: Cobalamin biosynthesis protein CbiG |
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Gene: ETAE_1997: Cobalamin biosynthesis protein CbiG |
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Gene: plu2992: Cobalamin biosynthesis protein CbiG |
Cobalamin biosynthesis protein CbiG |
| cbiH |
|
Gene: STM2027: Cobalt-precorrin-3b C17-methyltransferase |
Gene: CKO_00811: Cobalt-precorrin-3b C17-methyltransferase |
Gene: KPN_03192: Cobalt-precorrin-3b C17-methyltransferase |
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Gene: ETAE_1996: Cobalt-precorrin-3b C17-methyltransferase |
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Gene: plu2991: Cobalt-precorrin-3b C17-methyltransferase |
Cobalt-precorrin-3b C17-methyltransferase |
| cbiJ |
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Gene: STM2026: Cobalt-precorrin-6x reductase (EC 1.3.1.54) |
Gene: CKO_00812: Cobalt-precorrin-6x reductase (EC 1.3.1.54) |
Gene: KPN_03191: Cobalt-precorrin-6x reductase (EC 1.3.1.54) |
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Gene: ETAE_1995: Cobalt-precorrin-6x reductase (EC 1.3.1.54) |
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Gene: plu2990: Cobalt-precorrin-6x reductase (EC 1.3.1.54) |
Cobalt-precorrin-6x reductase (EC 1.3.1.54) |
| cbiK |
|
Gene: STM2025: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) |
Gene: CKO_00813: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) |
Gene: KPN_03190: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) |
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Gene: ETAE_1994: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) |
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Gene: plu2989: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) |
Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) |
| cbiL |
|
Gene: STM2024: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) |
Gene: CKO_00814: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) |
Gene: KPN_03189: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) |
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Gene: ETAE_1993: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) |
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Gene: plu2988: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) |
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) |
| cbiM |
|
Gene: STM2023: Substrate-specific component CbiM of cobalt ECF transporter |
Gene: CKO_00815: Substrate-specific component CbiM of cobalt ECF transporter |
Gene: KPN_03188: Substrate-specific component CbiM of cobalt ECF transporter |
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Gene: ETAE_1992: Substrate-specific component CbiM of cobalt ECF transporter |
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Substrate-specific component CbiM of cobalt ECF transporter |
| cbiN |
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Gene: STM2022: Additional substrate-specific component CbiN of cobalt ECF transporter |
Gene: CKO_00816: Additional substrate-specific component CbiN of cobalt ECF transporter |
Gene: KPN_03187: Additional substrate-specific component CbiN of cobalt ECF transporter |
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Gene: ETAE_1991: Additional substrate-specific component CbiN of cobalt ECF transporter |
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Additional substrate-specific component CbiN of cobalt ECF transporter |
| cbiQ |
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Gene: STM2021: Transmembrane component CbiQ of energizing module of cobalt ECF transporter |
Gene: CKO_00817: Transmembrane component CbiQ of energizing module of cobalt ECF transporter |
Gene: KPN_03186: Transmembrane component CbiQ of energizing module of cobalt ECF transporter |
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Gene: ETAE_1990: Transmembrane component CbiQ of energizing module of cobalt ECF transporter |
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Transmembrane component CbiQ of energizing module of cobalt ECF transporter |
| cbiO |
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Gene: STM2020: ATPase component CbiO of energizing module of cobalt ECF transporter |
Gene: CKO_00818: ATPase component CbiO of energizing module of cobalt ECF transporter |
Gene: KPN_03185: ATPase component CbiO of energizing module of cobalt ECF transporter |
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ATPase component CbiO of energizing module of cobalt ECF transporter |
| cbiP |
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Gene: STM2019: Cobyric acid synthase |
Gene: CKO_00819: Cobyric acid synthase |
Gene: KPN_03184: Cobyric acid synthase |
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*2
Edwardsiella tarda EIB202 Site: position = -369 score = 93.46 sequence = GCACCCGCAGGTGCA... Gene: ETAE_1848: Cobyric acid synthase Gene: ETAE_1989: ATPase component CbiO of energizing module of cobalt ECF transporter / Cobyric acid synthase |
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Gene: plu2987: Cobyric acid synthase |
Cobyric acid synthase |
| cobU |
Gene: b1993: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) |
Gene: STM2018: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) |
Gene: CKO_00820: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) |
Gene: KPN_03183: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) |
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Gene: ETAE_1988: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) |
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Gene: plu2986: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) |
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) |
| cobS |
Gene: b1992: Cobalamin synthase |
Gene: STM2017: Cobalamin synthase |
Gene: CKO_00821: Cobalamin synthase |
Gene: KPN_02464: Cobalamin synthase |
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Gene: ETAE_1546: Cobalamin synthase |
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Gene: plu2985: Cobalamin synthase |
Cobalamin synthase |
| cobT |
Gene: b1991: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
Gene: STM2016: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
Gene: CKO_00822: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
2
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_03182: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) Gene: KPN_02463: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
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Gene: ETAE_1847: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
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Gene: plu2980: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
| CRON 3. | |||||||||||||
| btuF |
|
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*
Citrobacter koseri ATCC BAA-895 Site: position = -408 score = 83.67 sequence = CGATACAGTCGCCAG... Gene: CKO_01267: Vitamin B12 ABC transporter, B12-binding component BtuF |
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Vitamin B12 ABC transporter, B12-binding component BtuF |
| btuC |
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Gene: CKO_01266: Vitamin B12 ABC transporter, permease component BtuC |
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Vitamin B12 ABC transporter, permease component BtuC |
| btuD |
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Gene: CKO_01265: Vitamin B12 ABC transporter, ATPase component BtuD |
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Vitamin B12 ABC transporter, ATPase component BtuD |
| petE |
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Gene: CKO_01264: Pseudoazurin precursor |
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Pseudoazurin precursor |
| petA |
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Gene: CKO_01263: Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) |
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Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) |
| petB |
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Gene: CKO_01262: Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) |
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Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) |
| petC |
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Gene: CKO_01261: ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit |
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ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |