Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing cobU gene

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Phylum: Proteobacteria
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Edwardsiella tarda EIB202
Position: -273
Score: 93.69
Sequence: ACCATGTAATAAGCC...
Locus tag: ETAE_2004
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: ETAE_2003
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: ETAE_2002
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: ETAE_2001
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: ETAE_2000
Name: cbiE
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Locus tag: ETAE_1999
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: ETAE_1998
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: ETAE_1997
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: ETAE_1996
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: ETAE_1995
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: ETAE_1994
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
Locus tag: ETAE_1993
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: ETAE_1992
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: ETAE_1991
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: ETAE_1990
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: ETAE_1989
Name: cbiOP
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter / Cobyric acid synthase
Locus tag: ETAE_1988
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
cbiA-cbiB-cbiC-cbiD-cbiE-cbiT-cbiF-cbiG-cbiH-cbiJ-cbiK-cbiL-cbiM-cbiN-cbiQ-cbiOP-cobU -273 93.7 ACCATGTAATAAGCC... ETAE_2004
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Position: -194
Score: 91.09
Sequence: TCGGCGAAACAAACC...
Locus tag: KPN_03200
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: KPN_03199
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: KPN_03198
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: KPN_03197
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: KPN_03196
Name: cbiE
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Locus tag: KPN_03195
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: KPN_03194
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: KPN_03193
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: KPN_03192
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: KPN_03191
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: KPN_03190
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
Locus tag: KPN_03189
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: KPN_03188
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: KPN_03187
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: KPN_03186
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: KPN_03185
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: KPN_03184
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: KPN_03183
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: KPN_03182
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
cbiA-cbiB-cbiC-cbiD-cbiE-cbiT-cbiF-cbiG-cbiH-cbiJ-cbiK-cbiL-cbiM-cbiN-cbiQ-cbiO-cbiP-cobU-cobT -194 91.1 TCGGCGAAACAAACC... KPN_03200
Photorhabdus luminescens subsp. laumondii TTO1
Position: -289
Score: 92.92
Sequence: CGGGTATAAACCGCC...
Locus tag: plu2999
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: plu2998
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: plu2997
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: plu2996
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: plu2995
Name: cbiE
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Locus tag: plu2994
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: plu2993
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: plu2992
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: plu2991
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: plu2990
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: plu2989
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
Locus tag: plu2988
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: plu2987
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: plu2986
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: plu2985
Name: cobS
Funciton: Cobalamin synthase
cbiA-cbiB-cbiC-cbiD-cbiE-cbiT-cbiF-cbiG-cbiH-cbiJ-cbiK-cbiL-cbiP-cobU-cobS -289 92.9 CGGGTATAAACCGCC... plu2999
Salmonella typhimurium LT2
Position: -273
Score: 100.98
Sequence: GCCATAACGTAAACC...
Locus tag: STM2035
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: STM2034
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: STM2033
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: STM2032
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: STM2031
Name: cbiE
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Locus tag: STM2030
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: STM2029
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: STM2028
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: STM2027
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: STM2026
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: STM2025
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
Locus tag: STM2024
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: STM2023
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: STM2022
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: STM2021
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: STM2020
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: STM2019
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: STM2018
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: STM2017
Name: cobS
Funciton: Cobalamin synthase
Locus tag: STM2016
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
cbiA-cbiB-cbiC-cbiD-cbiE-cbiT-cbiF-cbiG-cbiH-cbiJ-cbiK-cbiL-cbiM-cbiN-cbiQ-cbiO-cbiP-cobU-cobS-cobT -273 101 GCCATAACGTAAACC... STM2035