Regulog RocR - Bacillales

Properties
Regulator type:	Transcription factor
Regulator family:	Fis
Regulation mode:	activator
Biological process:	Arginine degradation; Ornithine degradation
Effector:	Ornithine; L-citrulline
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 26 sites [see more]

Member of regulog collections

By taxonomy - Bacillales
By TF family - Fis
By effector - Ornithine
By effector - L-citrulline
By pathway - Arginine degradation
By pathway - Ornithine degradation

Statistics of regulated genes
Genome	Genes	Operons
Bacillus subtilis subsp. subtilis str. 168	7	3
Bacillus amyloliquefaciens FZB42	7	3
Bacillus pumilus SAFR-032	3	2
Bacillus licheniformis DSM 13	4	2
Anoxybacillus flavithermus WK1
Geobacillus kaustophilus HTA426	5	2
Bacillus cereus ATCC 14579	1	1
Bacillus halodurans C-125	5	2
Bacillus clausii KSM-K16	2	2
Oceanobacillus iheyensis HTE831
Paenibacillus sp. JDR-2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes												Function

CRON 1.
rocC	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU37760: Arginine/ornithine permease	Bacillus amyloliquefaciens FZB42 Gene: RBAM_034960: Arginine/ornithine permease	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	* Geobacillus kaustophilus HTA426 Site: position = -93 score = 8.05777 sequence = TGAAAAAT-(1)-ATTTTGCA Site: position = -168 score = 7.69112 sequence = TGAAAAAA-(1)-TTTTTGCT Gene: GK0186: Arginine/ornithine permease	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Arginine/ornithine permease
rocA	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -213 score = 8.57841 sequence = CGCAAAAT-(1)-ATTTTGCA Site: position = -169 score = 7.97041 sequence = CGCAAAAT-(1)-AATTTGCG Gene: BSU37780: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)	* Bacillus amyloliquefaciens FZB42 Site: position = -199 score = 7.57413 sequence = CGCAAAGA-(1)-ATTTTGCA Site: position = -165 score = 7.8404 sequence = CGCAAAAT-(1)-TCTTTGCG Gene: RBAM_034980: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)	Bacillus pumilus SAFR-032 Gene: BPUM_0301: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)	Bacillus licheniformis DSM 13 Gene: BLi00374: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)	Anoxybacillus flavithermus WK1 Gene: Aflv_0249: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)	* Geobacillus kaustophilus HTA426 Site: position = -37 score = 7.68317 sequence = CGAAAAAT-(1)-TTTTTGCC Gene: GK0187: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)	Bacillus cereus ATCC 14579 Gene: BC0344: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)	Bacillus halodurans C-125 Gene: BH3940: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)	Bacillus clausii KSM-K16 Gene: ABC0965: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)	Oceanobacillus iheyensis HTE831 Gene: OB1349: Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)	Paenibacillus sp. JDR-2	Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)
rocD	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -175 score = 7.89341 sequence = TGCAAAAG-(1)-ATTTTGCA Gene: BSU40340: Ornithine aminotransferase (EC 2.6.1.13)	* Bacillus amyloliquefaciens FZB42 Site: position = -177 score = 8.71467 sequence = CGCAAAAA-(1)-ATTTTGCG Gene: RBAM_037250: Ornithine aminotransferase (EC 2.6.1.13)	* Bacillus pumilus SAFR-032 Site: position = -137 score = 7.20123 sequence = TGCAAAGA-(1)-ATTTTGCT Gene: BPUM_3060: Ornithine aminotransferase (EC 2.6.1.13)	* Bacillus licheniformis DSM 13 Site: position = -142 score = 8.71467 sequence = CGCAAAAT-(0)-TTTTTGCG Gene: BLi00422: Ornithine aminotransferase (EC 2.6.1.13)	Anoxybacillus flavithermus WK1 Gene: Aflv_2206: Ornithine aminotransferase (EC 2.6.1.13)	Geobacillus kaustophilus HTA426 Gene: GK0188: Ornithine aminotransferase (EC 2.6.1.13)	Bacillus cereus ATCC 14579 Gene: BC1149: Ornithine aminotransferase (EC 2.6.1.13)	* Bacillus halodurans C-125 Site: position = -172 score = 7.96304 sequence = AGAAAAAT-(1)-ATTTTTCG Site: position = -215 score = 7.31976 sequence = TGCAAATT-(1)-TTTTTTCG Gene: BH3943: Ornithine aminotransferase (EC 2.6.1.13)	* Bacillus clausii KSM-K16 Site: position = -173 score = 8.4603 sequence = CGCAAAAA-(1)-ATTTTTCG Site: position = -140 score = 7.69112 sequence = TGCAAAAA-(1)-TTTTTTCT Gene: ABC0017: Ornithine aminotransferase (EC 2.6.1.13)	Oceanobacillus iheyensis HTE831 Gene: OB2287: Ornithine aminotransferase (EC 2.6.1.13)	Paenibacillus sp. JDR-2 Gene: Pjdr2_3902: Ornithine aminotransferase (EC 2.6.1.13)	Ornithine aminotransferase (EC 2.6.1.13)
rocG	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU37790: NAD-specific glutamate dehydrogenase (EC 1.4.1.2)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_034990: NAD-specific glutamate dehydrogenase (EC 1.4.1.2)	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426 Gene: GK0189: NAD-specific glutamate dehydrogenase (EC 1.4.1.2)	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH3942: NAD-specific glutamate dehydrogenase (EC 1.4.1.2)	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	NAD-specific glutamate dehydrogenase (EC 1.4.1.2)
BH3941	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125 Gene: BH3941: Hypothetical protein	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Hypothetical protein
rocE	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU40330: Arginine/ornithine/gamma-aminobutyrate permease	Bacillus amyloliquefaciens FZB42 Gene: RBAM_037240: Arginine/ornithine/gamma-aminobutyrate permease	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi00423: Arginine/ornithine/gamma-aminobutyrate permease	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579 Gene: BC0643: Arginine/ornithine/gamma-aminobutyrate permease	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Arginine/ornithine/gamma-aminobutyrate permease
rocF	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU40320: Arginase (EC 3.5.3.1)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_037230: Arginase (EC 3.5.3.1)	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13 Gene: BLi00424: Arginase (EC 3.5.3.1)	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579 Gene: BC0185: Arginase (EC 3.5.3.1)	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Arginase (EC 3.5.3.1)
rocB	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU37770: Putative N-deacylase involved in arginine and ornithine utilization	Bacillus amyloliquefaciens FZB42 Gene: RBAM_034970: Putative N-deacylase involved in arginine and ornithine utilization	Bacillus pumilus SAFR-032	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Putative N-deacylase involved in arginine and ornithine utilization
rocC	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032 Gene: BPUM_3059: Arginine/ornithine permease	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Arginine/ornithine permease

CRON 2.
rocR	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -82 score = 7.89341 sequence = TGCAAAAT-(1)-CTTTTGCA Gene: BSU40350: Transcriptional activator of arginine utilization, Fis family	* Bacillus amyloliquefaciens FZB42 Site: position = -59 score = 8.71467 sequence = CGCAAAAT-(1)-TTTTTGCG Gene: RBAM_037260: Transcriptional activator of arginine utilization, Fis family	* Bacillus pumilus SAFR-032 Site: position = -89 score = 7.20123 sequence = AGCAAAAT-(1)-TCTTTGCA Gene: BPUM_3061: Transcriptional activator of arginine utilization, Fis family	* Bacillus licheniformis DSM 13 Site: position = -22 score = 8.71467 sequence = CGCAAAAA-(0)-ATTTTGCG Gene: BLi00421: Transcriptional activator of arginine utilization, Fis family	Anoxybacillus flavithermus WK1	* Geobacillus kaustophilus HTA426 Site: position = -159 score = 8.05777 sequence = TGCAAAAT-(1)-ATTTTTCA Site: position = -84 score = 7.69112 sequence = AGCAAAAA-(1)-TTTTTTCA Gene: GK0185: Transcriptional activator of arginine utilization, Fis family	* Bacillus cereus ATCC 14579 Site: position = -87 score = 8.21177 sequence = AGCAAAAA-(1)-TTTTTGCG Gene: BC0473: Transcriptional activator of arginine utilization, Fis family	* Bacillus halodurans C-125 Site: position = -116 score = 7.96304 sequence = CGAAAAAT-(1)-ATTTTTCT Site: position = -73 score = 7.31976 sequence = CGAAAAAA-(1)-AATTTGCA Gene: BH3944: Transcriptional activator of arginine utilization, Fis family	* Bacillus clausii KSM-K16 Site: position = -95 score = 7.69112 sequence = AGAAAAAA-(1)-TTTTTGCA Site: position = -62 score = 8.4603 sequence = CGAAAAAT-(1)-TTTTTGCG Gene: ABC0016: Transcriptional activator of arginine utilization, Fis family	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Transcriptional activator of arginine utilization, Fis family

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog RocR - Bacillales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --