Regulog MprA - Enterobacteriales

Properties
Regulator type:	Transcription factor
Regulator family:	MarR
Regulation mode:	repressor
Biological process:	Multidrug resistance
Effector:	2,4-Dinitrophenol; Carbonyl cyanide m-chlorophenylhydrazone
Phylum:	Proteobacteria/gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 25 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By TF family - MarR
By effector - 2,4-Dinitrophenol
By effector - Carbonyl cyanide m-chlorophenylhydrazone
By pathway - Multidrug resistance

Statistics of regulated genes
Genome	Genes	Operons
Escherichia coli str. K-12 substr. MG1655	5	2
Salmonella typhimurium LT2	5	2
Citrobacter koseri ATCC BAA-895	5	2
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	5	2
Enterobacter sp. 638	5	2
Erwinia amylovora ATCC 49946	5	2
Yersinia pestis KIM	3	2
Serratia proteamaculans 568	6	2
Erwinia carotovora subsp. atroseptica SCRI1043	5	2
Edwardsiella tarda EIB202	5	2
Proteus mirabilis HI4320	2	1
Photorhabdus luminescens subsp. laumondii TTO1	5	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes													Function

CRON 1.
mprA	* Escherichia coli str. K-12 substr. MG1655 Site: position = -51 score = 6.91961 sequence = ATTTGTCACTGTCGTTACTATA Gene: b2684: Transcriptional repressor mprA (EmrR protein)	* Salmonella typhimurium LT2 Site: position = -51 score = 6.91961 sequence = ATTTGTCACTGTCGTTACTATA Gene: STM2813: Transcriptional repressor mprA (EmrR protein)	* Citrobacter koseri ATCC BAA-895 Site: position = -51 score = 6.91961 sequence = ATTTGTCACTGTCGTTACTATA Gene: CKO_04033: Transcriptional repressor mprA (EmrR protein)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -150 score = 6.18798 sequence = ATTTGTCACAATAGTTATTATA Gene: KPN_03013: Transcriptional repressor mprA (EmrR protein)	* Enterobacter sp. 638 Site: position = -51 score = 6.91961 sequence = ATTTGTCACTGTCGTTACTATA Gene: Ent638_3162: Transcriptional repressor mprA (EmrR protein)	* Erwinia amylovora ATCC 49946 Site: position = -51 score = 5.22143 sequence = ATTAATCACCATCATTATTATA Gene: EAM_2603: Transcriptional repressor mprA (EmrR protein)	* Yersinia pestis KIM Site: position = -26 score = 6.14797 sequence = ATTAGTAACTATCGTTACTGTA Gene: y0923: Transcriptional repressor mprA (EmrR protein)	* Serratia proteamaculans 568 Site: position = -50 score = 6.06398 sequence = ATTAATCACTATCGTTACTATC Gene: Spro_3741: Transcriptional repressor mprA (EmrR protein)	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -53 score = 5.37255 sequence = TTTAGTAACATTAGTTACTATG Gene: ECA3511: Transcriptional repressor mprA (EmrR protein)	* Edwardsiella tarda EIB202 Site: position = -51 score = 5.11508 sequence = ACTGATAACCAAAGTTACTATA Gene: ETAE_2765: Transcriptional repressor mprA (EmrR protein)	Proteus mirabilis HI4320 Gene: PMI0407: Transcriptional repressor mprA (EmrR protein)	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -51 score = 4.08136 sequence = TTTGATAACAAAAGTTATCTTA Gene: plu1277: Transcriptional repressor mprA (EmrR protein)	Transcriptional repressor mprA (EmrR protein)
Spro_3742	Escherichia coli str. K-12 substr. MG1655	Salmonella typhimurium LT2	Citrobacter koseri ATCC BAA-895	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568 Gene: Spro_3742: RND efflux system, outer membrane lipoprotein, NodT family	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	RND efflux system, outer membrane lipoprotein, NodT family
emrA	Escherichia coli str. K-12 substr. MG1655 Gene: b2685: multidrug resistance protein A	Salmonella typhimurium LT2 Gene: STM2814: multidrug resistance protein A	Citrobacter koseri ATCC BAA-895 Gene: CKO_04034: multidrug resistance protein A	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_03014: multidrug resistance protein A	Enterobacter sp. 638 Gene: Ent638_3163: multidrug resistance protein A	Erwinia amylovora ATCC 49946 Gene: EAM_2604: multidrug resistance protein A	Yersinia pestis KIM Gene: y0922: multidrug resistance protein A	Serratia proteamaculans 568 Gene: Spro_3743: multidrug resistance protein A	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA3512: multidrug resistance protein A	Edwardsiella tarda EIB202 Gene: ETAE_2766: multidrug resistance protein A	Proteus mirabilis HI4320 Gene: PMI0403: multidrug resistance protein A	Photorhabdus luminescens subsp. laumondii TTO1 Gene: plu1276: multidrug resistance protein A	multidrug resistance protein A
emrB	Escherichia coli str. K-12 substr. MG1655 Gene: b2686: multidrug resistance protein B	Salmonella typhimurium LT2 Gene: STM2815: multidrug resistance protein B	Citrobacter koseri ATCC BAA-895 Gene: CKO_04035: multidrug resistance protein B	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_03015: multidrug resistance protein B	Enterobacter sp. 638 Gene: Ent638_3164: multidrug resistance protein B	Erwinia amylovora ATCC 49946 Gene: EAM_2605: multidrug resistance protein B	Yersinia pestis KIM Gene: y0921: multidrug resistance protein B	Serratia proteamaculans 568 Gene: Spro_3744: multidrug resistance protein B	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA3513: multidrug resistance protein B	Edwardsiella tarda EIB202 Gene: ETAE_2767: multidrug resistance protein B	Proteus mirabilis HI4320 Gene: PMI0402: multidrug resistance protein B	Photorhabdus luminescens subsp. laumondii TTO1 Gene: plu1275: multidrug resistance protein B	multidrug resistance protein B

CRON 2.
acrA	* Escherichia coli str. K-12 substr. MG1655 Site: position = -106 score = 6.43495 sequence = ATTTGTGAATGTATGTACCATA Gene: b0463: acriflavin resistance protein A	* Salmonella typhimurium LT2 Site: position = -106 score = 5.87554 sequence = ATTTATGGATGTATGTACCATA Gene: STM0476: acriflavin resistance protein A	* Citrobacter koseri ATCC BAA-895 Site: position = -106 score = 6.07744 sequence = ATTTGTGGATGTATGTACCATA Gene: CKO_02688: acriflavin resistance protein A	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -107 score = 6.43495 sequence = ATTTGTGAATGTATGTACCATA Gene: KPN_00444: acriflavin resistance protein A	* Enterobacter sp. 638 Site: position = -107 score = 5.687 sequence = ATTTATGAATGTATGTAACATA Gene: Ent638_0943: acriflavin resistance protein A	* Erwinia amylovora ATCC 49946 Site: position = -98 score = 6.2662 sequence = ATTTGCGAATGTATGTACTATA Gene: EAM_1017: acriflavin resistance protein A	* Yersinia pestis KIM Site: position = -109 score = 5.55169 sequence = ATTCACGAATGTATGTACCATA Gene: y1050: acriflavin resistance protein A	* Serratia proteamaculans 568 Site: position = -107 score = 5.39608 sequence = ATTCGCGTATGTATGTACCATA Gene: Spro_1127: acriflavin resistance protein A	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -107 score = 4.47272 sequence = ATTCAAGTATGTATGTAACATA Gene: ECA1170: acriflavin resistance protein A	* Edwardsiella tarda EIB202 Site: position = -106 score = 5.92233 sequence = ATTGATGAATGTATGTACCATA Gene: ETAE_1011: acriflavin resistance protein A	* Proteus mirabilis HI4320 Site: position = -117 score = 3.84203 sequence = GATTTTGACTGAAGTTAATTTA Site: position = -90 score = 5.49624 sequence = ATTCATGTATGTTTGTACTATA Site: position = -58 score = 3.74866 sequence = ATTCATCAACTTAATTATTTTT Gene: PMI0132: acriflavin resistance protein A	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -94 score = 4.75496 sequence = ATTCACGTATGTTTGTATTATA Gene: plu3851: acriflavin resistance protein A	acriflavin resistance protein A
acrB	Escherichia coli str. K-12 substr. MG1655 Gene: b0462: acriflavin resistance protein B	Salmonella typhimurium LT2 Gene: STM0475: acriflavin resistance protein B	Citrobacter koseri ATCC BAA-895 Gene: CKO_02689: acriflavin resistance protein B	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_00443: acriflavin resistance protein B	Enterobacter sp. 638 Gene: Ent638_0942: acriflavin resistance protein B	Erwinia amylovora ATCC 49946 Gene: EAM_1016: acriflavin resistance protein B	Yersinia pestis KIM Gene: y1049: acriflavin resistance protein B	Serratia proteamaculans 568 Gene: Spro_1126: acriflavin resistance protein B	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA1169: acriflavin resistance protein B	Edwardsiella tarda EIB202 Gene: ETAE_1010: acriflavin resistance protein B	Proteus mirabilis HI4320 Gene: PMI0131: acriflavin resistance protein B	Photorhabdus luminescens subsp. laumondii TTO1 Gene: plu3852: acriflavin resistance protein B	acriflavin resistance protein B

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog MprA - Enterobacteriales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --