Regulog SdaR - Enterobacteriales

Properties
Regulator type:	Transcription factor
Regulator family:	SdaR
Regulation mode:	activator
Biological process:	Glucarate utilization; Galactarate utilization
Effector:	Glycerate
Phylum:	Proteobacteria/gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 31 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By trascription factor - SdaR
By TF family - SdaR
By effector - Glycerate
By pathway - Glucarate utilization
By pathway - Galactarate utilization

Statistics of regulated genes
Genome	Genes	Operons
Escherichia coli str. K-12 substr. MG1655	9	4
Salmonella typhimurium LT2	9	4
Citrobacter koseri ATCC BAA-895	9	4
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	10	4
Enterobacter sp. 638	10	4
Erwinia amylovora ATCC 49946
Yersinia pestis KIM
Serratia proteamaculans 568
Erwinia carotovora subsp. atroseptica SCRI1043	8	4
Edwardsiella tarda EIB202
Proteus mirabilis HI4320
Photorhabdus luminescens subsp. laumondii TTO1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes													Function

CRON 1.
garD	* Escherichia coli str. K-12 substr. MG1655 Site: position = -250 score = 4.50599 sequence = CATTGTGCAAATGCTAATTT Site: position = -208 score = 5.98822 sequence = TTTTGAGCATATGCACATAA Gene: b3128: D-galactarate dehydratase (EC 4.2.1.42)	* Salmonella typhimurium LT2 Site: position = -276 score = 4.77058 sequence = CATTGTGCAAACGCTCATTA Site: position = -233 score = 5.12915 sequence = TTTTGAGCATACGCCCATGA Gene: STM3250: D-galactarate dehydratase (EC 4.2.1.42)	* Citrobacter koseri ATCC BAA-895 Site: position = -223 score = 5.5751 sequence = TTTTGAGCATTTGCACAACG Gene: CKO_04527: D-galactarate dehydratase (EC 4.2.1.42)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -206 score = 4.69404 sequence = AATTGTGCTTATGCCATAAG Gene: KPN_03540: D-galactarate dehydratase (EC 4.2.1.42)	* Enterobacter sp. 638 Site: position = -224 score = 5.37345 sequence = ATTTGAGCATATGCACAACC Gene: Ent638_3570: D-galactarate dehydratase (EC 4.2.1.42)	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -140 score = 4.15729 sequence = CTTAGGTCAATTGCATAATG Site: position = -316 score = 4.55689 sequence = GTTGGTGCACTTGCCCTATA Gene: ECA3578: D-galactarate dehydratase (EC 4.2.1.42)	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	D-galactarate dehydratase (EC 4.2.1.42)

CRON 2.
gudX	Escherichia coli str. K-12 substr. MG1655 Gene: b2788: Glucarate dehydratase related protein (EC 4.2.1.-)	Salmonella typhimurium LT2 Gene: STM2961: Glucarate dehydratase related protein (EC 4.2.1.-)	Citrobacter koseri ATCC BAA-895 Gene: CKO_04142: Glucarate dehydratase related protein (EC 4.2.1.-)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_03131: Glucarate dehydratase related protein (EC 4.2.1.-)	Enterobacter sp. 638 Gene: Ent638_3241: Glucarate dehydratase related protein (EC 4.2.1.-)	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -358 score = 4.10233 sequence = TGCTGGGCTATTGCCCAATG Gene: ECA3576: Glucarate dehydratase related protein (EC 4.2.1.-)	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Glucarate dehydratase related protein (EC 4.2.1.-)
gudD	Escherichia coli str. K-12 substr. MG1655 Gene: b2787: Glucarate dehydratase (EC 4.2.1.40)	Salmonella typhimurium LT2 Gene: STM2960: Glucarate dehydratase (EC 4.2.1.40)	Citrobacter koseri ATCC BAA-895 Gene: CKO_04141: Glucarate dehydratase (EC 4.2.1.40)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_03130: Glucarate dehydratase (EC 4.2.1.40)	Enterobacter sp. 638 Gene: Ent638_3240: Glucarate dehydratase (EC 4.2.1.40)	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA3575: Glucarate dehydratase (EC 4.2.1.40)	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Glucarate dehydratase (EC 4.2.1.40)
garL	Escherichia coli str. K-12 substr. MG1655 Gene: b3126: 2-dehydro-3-deoxyglucarate aldolase (EC 4.1.2.20)	* Salmonella typhimurium LT2 Site: position = -316 score = 5.12915 sequence = TCATGGGCGTATGCTCAAAA Site: position = -273 score = 4.77058 sequence = TAATGAGCGTTTGCACAATG Gene: STM3249: 2-dehydro-3-deoxyglucarate aldolase (EC 4.1.2.20)	* Citrobacter koseri ATCC BAA-895 Site: position = -203 score = 5.5751 sequence = CGTTGTGCAAATGCTCAAAA Gene: CKO_04523: 2-dehydro-3-deoxyglucarate aldolase (EC 4.1.2.20)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_03538: 2-dehydro-3-deoxyglucarate aldolase (EC 4.1.2.20)	Enterobacter sp. 638 Gene: Ent638_3568: 2-dehydro-3-deoxyglucarate aldolase (EC 4.1.2.20)	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA3574: 2-dehydro-3-deoxyglucarate aldolase (EC 4.1.2.20)	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	2-dehydro-3-deoxyglucarate aldolase (EC 4.1.2.20)
garR	Escherichia coli str. K-12 substr. MG1655 Gene: b3125: 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60)	Salmonella typhimurium LT2 Gene: STM3248: 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60)	Citrobacter koseri ATCC BAA-895 Gene: CKO_04522: 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_03537: 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60)	Enterobacter sp. 638 Gene: Ent638_3567: 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60)	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA3573: 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60)	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60)
garK	Escherichia coli str. K-12 substr. MG1655 Gene: b3124: Glycerate kinase (EC 2.7.1.31)	2 Salmonella typhimurium LT2 Gene: STM3247: Glycerate kinase (EC 2.7.1.31) Gene: STM2959: Glycerate kinase (EC 2.7.1.31)	2 Citrobacter koseri ATCC BAA-895 Gene: CKO_04140: Glycerate kinase (EC 2.7.1.31) Gene: CKO_04521: Glycerate kinase (EC 2.7.1.31)	2 Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_03129: Glycerate kinase (EC 2.7.1.31) Gene: KPN_03536: Glycerate kinase (EC 2.7.1.31)	2 Enterobacter sp. 638 Gene: Ent638_3239: Glycerate kinase (EC 2.7.1.31) Gene: Ent638_3566: Glycerate kinase (EC 2.7.1.31)	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA3572: Glycerate kinase (EC 2.7.1.31)	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Glycerate kinase (EC 2.7.1.31)
garP	* Escherichia coli str. K-12 substr. MG1655 Site: position = -144 score = 4.50599 sequence = AAATTAGCATTTGCACAATG Site: position = -186 score = 5.98822 sequence = TTATGTGCATATGCTCAAAA Gene: b3127: D-galactarate permease, MFS family	Salmonella typhimurium LT2	Citrobacter koseri ATCC BAA-895	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -206 score = 4.69404 sequence = CTTATGGCATAAGCACAATT Gene: KPN_03539: D-galactarate permease, MFS family	* Enterobacter sp. 638 Site: position = -208 score = 5.37345 sequence = GGTTGTGCATATGCTCAAAT Gene: Ent638_3569: D-galactarate permease, MFS family	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	D-galactarate permease, MFS family
gudP	* Escherichia coli str. K-12 substr. MG1655 Site: position = -385 score = 4.7362 sequence = TTTCAGGCAAATGCCAGTAA Gene: b2789: D-glucarate permease, MFS family	* Salmonella typhimurium LT2 Site: position = -376 score = 5.52925 sequence = CTTTGTGCATATGCCCGCAA Gene: STM2962: D-glucarate permease, MFS family	* Citrobacter koseri ATCC BAA-895 Site: position = -388 score = 4.94857 sequence = CATCAGGCATTTGCCCTAAA Gene: CKO_04143: D-glucarate permease, MFS family	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -376 score = 4.38968 sequence = CTTTAGGCAAACGCCACAAT Site: position = -221 score = 4.5698 sequence = TTTCAGGCATTCGCCACAAA Gene: KPN_03132: D-glucarate permease, MFS family	* Enterobacter sp. 638 Site: position = -240 score = 4.89438 sequence = CGTTGTGCTTATGCCTCAAA Gene: Ent638_3242: D-glucarate permease, MFS family	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -440 score = 4.15729 sequence = CATTATGCAATTGACCTAAG Site: position = -264 score = 4.55689 sequence = TATAGGGCAAGTGCACCAAC Gene: ECA3577: D-glucarate permease, MFS family	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	D-glucarate permease, MFS family

CRON 3.
sdaR	* Escherichia coli str. K-12 substr. MG1655 Site: position = -69 score = 5.3349 sequence = CTTTAGGCATTTGCACAATG Gene: b0162: Glycerate-responsive transcriptional regulator for hexarate utilization, SdaR family	* Salmonella typhimurium LT2 Site: position = -71 score = 5.7879 sequence = TTTTGTGCATTTGCACAATG Gene: STM0210: Glycerate-responsive transcriptional regulator for hexarate utilization, SdaR family	* Citrobacter koseri ATCC BAA-895 Site: position = -17 score = 5.10846 sequence = GTTTGTGCAGATGCACAATG Gene: CKO_03205: Glycerate-responsive transcriptional regulator for hexarate utilization, SdaR family	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -17 score = 5.40889 sequence = CTTAGTGCAAATGCACAATG Gene: KPN_00177: Glycerate-responsive transcriptional regulator for hexarate utilization, SdaR family	* Enterobacter sp. 638 Site: position = -71 score = 5.30531 sequence = CTTTGTGCATTCGCACAATG Gene: Ent638_0702: Glycerate-responsive transcriptional regulator for hexarate utilization, SdaR family	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -80 score = 4.29729 sequence = CTTTGTTAATTTGCACAATG Gene: ECA3300: Glycerate-responsive transcriptional regulator for hexarate utilization, SdaR family	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Glycerate-responsive transcriptional regulator for hexarate utilization, SdaR family

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog SdaR - Enterobacteriales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --