Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagated regulons of Salmonella enterica subsp. enterica serovar Typhi str. M223

Type Regulator Effector Pathway Genes Sites
TF AcrR Rhodamine 6G; Ethidium bromide; Proflavin Multidrug resistance 1 1
TF AllR Allantoin Allantoin utilization 2 2
TF AraC Arabinose Arabinose utilization 1 2
TF ArgR Arginine Arginine biosynthesis; Arginine degradation 10 21
TF BirA Biotin Biotin biosynthesis 1 1
TF Crp Cyclic 3',5'-AMP Carbon catabolism 228 545
TF CueR Copper ion, (Cu+) Copper resistance 1 1
TF DeoR Deoxyribonucleoside utilization 2 2
TF ExuR Galacturonate Galacturonate utilization 1 2
TF FabR Unsaturated acyl-ACP; Unsaturated acyl-CoA Fatty acid biosynthesis 2 2
TF FadR Palmitoyl-CoA; Oleoyl-CoA Fatty acid degradation 7 10
TF Fnr Oxygen Energy metabolism; Anaerobic metabolism 86 150
TF FruR Fructose-1-phosphate; Fructose-1,6-diphosphate Central carbohydrate metabolism 20 26
TF FucR L-fuculose-1-phosphate Fucose utilization 2 2
TF GalR/GalS Galactose Galactose utilization 4 5
TF GcvA Glycine Glycine metabolism 1 1
TF GlpR Glycerol 3-phosphate Glycerol utilization 4 5
TF GntR Gluconate Gluconate utilization 3 5
TF HexR 2-keto-3-deoxy-6-phosphogluconate Central carbohydrate metabolism 4 4
TF HutC cis-Urocanic acid Histidine utilization 2 3
TF IclR Pyruvate; Glyoxylate Glyoxylate bypass 1 1
TF IlvY 2-Acetolactate Branched-chain amino acid biosynthesis 2 4
TF IscR Iron-sulfur cluster redox state Iron-sulfur cluster biogenesis 2 3
TF KdgR 2-keto-3-deoxygluconate Pectin and polygalacturonate utlization 10 13
TF LeuO Guanosine 3',5'-bis(diphosphate) 3 7
TF LexA DNA damage SOS response 19 23
TF LldR L-lactate Lactate utilization 1 1
TF LysR LL-2,6-Diaminopimelate Lysine biosynthesis 2 2
TF MarR Salicylate; Tetracycline; Chloramphenicol Antibiotic resistance 1 2
TF MetR Homocysteine Methionine biosynthesis 5 8
TF MntR Manganese ion, (Mn2+) Manganese homeostasis 3 3
TF ModE Molybdate Molybdopterin biosynthesis; Molybdenum homeostasis 4 5
TF MprA 2,4-Dinitrophenol; Carbonyl cyanide m-chlorophenylhydrazone Multidrug resistance 2 2
TF NadR NAD NAD biosynthesis 2 2
TF NagC N-acetylglucosamine-6-phosphate N-acetylglucosamine utilization 6 8
TF NanR N-acetylneuraminic acid Sialic acid utilization 1 1
TF NarP Nitrate; Nitrite Nitrate and nitrite respiration 22 28
TF NhaR Potassium ion Osmotic stress response 1 1
TF NikR Nickel ion, (Ni2+) Nickel homeostasis 1 1
TF NorR Nitric oxide Nitrosative stress response 2 3
TF NrdR Deoxyribonucleotides Ribonucleotide reductases 3 4
TF NsrR Nitric oxide Nitrosative stress response 10 16
TF NtrC Phosphorylated NtrB, signal histidine kinase Nitrogen assimilation 6 13
TF PdhR Pyruvate Pyruvate metabolism 4 4
TF PhnR 2-aminoethylphosphonate Phosphonate utilization; 2-aminoethylphosphonate utilization 3 3
TF PurR Hypoxanthine; Guanine Purine metabolism 23 30
TF QorR Energy metabolism 2 2
TF RbsR Ribose Ribose utilization 1 1
TF RcnR Nickel ion, (Ni2+); Cobalt ion, (Co2+) Cobalt resistance; Nickel resistance 1 1
TF RhaR Rhamnose Rhamnose utilization 2 2
TF RhaS Rhamnose Rhamnose utilization 3 3
TF SdaR Glycerate Glucarate utilization; Galactarate utilization 2 4
TF SiaR Glucosamine-6-phosphate Sialic acid utilization 1 1
TF SoxR Paraquat Superoxide stress response 2 2
TF TreR Trehalose-6-phosphate Trehalose utilization 1 1
TF TrpR Tryptophan Tryptophan biosynthesis 5 5
TF TyrR Tyrosine; Phenylalanine Aromatic amino acid metabolism 8 14
TF UlaR Ascorbate-6-phosphate Ascorbate utilization 1 2
TF UxuR Glucuronate Glucuronate utilization 2 5
TF XapR Deoxyinosine; Xanthosine Xanthosine utilization 1 1
TF YiaJ Ascorbate-6-phosphate L-lyxose utilization 1 1
TF Zur Zinc ion, (Zn2+) Zinc homeostasis 3 3
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