Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagated regulons of Streptococcus pyogenes MGAS9429

Type Regulator Effector Pathway Genes Sites
TF AdcR Zinc ion, (Zn2+) Zinc homeostasis 7 8
TF AgaR2 N-acetylgalactosamine N-acetylgalactosamine utilization 1 1
TF ArgR Arginine Arginine biosynthesis; Arginine degradation 6 12
TF BirA Biotin Biotin biosynthesis 2 2
TF CcpA Fructose-1,6-bisphosphate; HPr, phosphocarrier protein Global catabolite repression 82 118
TF CelR CelB, cellobiose-specific PTS component EIIB; HPr, phosphocarrier protein Cellobiose utilization 2 2
TF CmbR O-acetyl-L-serine Cysteine metabolism 5 6
TF CodY Guanosine triphosphate; Branched-chain amino acids Amino acid metabolism 9 11
TF CopR Copper ion, (Cu2+) Copper homeostasis 1 2
TF CtsR Heat shock Heat shock response 3 3
TF FabT Long-chain acyl-ACP Fatty acid biosynthesis 3 4
TF FruR Fructose-6-phosphate Fructose utilization 1 3
TF GlnR Phosphorylated NtrB, signal histidine kinase Nitrogen assimilation 1 1
TF HrcA Heat shock Heat shock response 2 3
TF LacR D-galactose-6-phosphate Lactose utilization; Galactose utilization 3 10
TF MalR Maltose Maltose utilization; Maltodextrin utilization 5 5
TF MntR Manganese ion, (Mn2+) Manganese homeostasis 3 5
TF MtaR Homocysteine Methionine metabolism 1 2
TF NagR N-acetylglucosamine-6-phosphate N-acetylglucosamine utilization 2 3
TF NanR N-acetylneuraminic acid Sialic acid utilization 1 1
TF NiaR Niacin NAD biosynthesis 2 2
TF NrdR Deoxyribonucleotides Deoxyribonucleotide biosynthesis 2 4
TF PerR Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide Iron homeostasis; Manganese homeostasis; Oxidative stress response 6 14
TF PflR Formate metabolism 1 1
TF PipR Phage infection protein 2 3
TF PurR 5-phosphoribosyl 1-pyrophosphate Purine metabolism 5 7
TF RbsR2 Ribose Ribose utilization 1 1
TF RegR Hyaluronate oligosaccharide phosphate Hyaluronate utilization 3 7
TF Rex NADH Energy metabolism 13 21
TF SAG1910 unknown 1 1
TF ScrR Sucrose-6-phosphate Sucrose utilization 2 2
TF SczA Zinc ion, (Zn2+) Zinc resistance 2 2
TF SgaR HPr, phosphocarrier protein; SgaB, ascorbate-specific PTS system EIIB component Ascorbate utilization 3 3
TF SgaR2 SgaB2, ascorbate-specific PTS system, EIIB component; HPr, phosphocarrier protein Ascorbate utilization 1 1
TF SPy1285 Transport 1 1
TF TreR Trehalose-6-phosphate Trehalose utilization 2 2
TF YjdR Multidrug resistance 1 1
TF YwzG Transport 1 3
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