Propagation of PurR regulog to Streptococcus pyogenes MGAS9429
| Source regulog: | PurR - Streptococcaceae |
| Regulator type: | Transcription factor |
| Regulator family: | PurR |
| Regulation mode: | repressor |
| Biological process: | Purine metabolism |
| Effector: | 5-phosphoribosyl 1-pyrophosphate |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Streptococcus pyogenes MGAS9429 |
| Orthologous TF(s) | MGAS9429_Spy0230 |
| Regulated genes | 5 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -78
Score: 4.7 Sequence: AAAAACGAACCTT
Position: 14
Score: 4 Sequence: AAAGGCGAATAAT
Locus tag: MGAS9429_Spy0022
|
||||
| MGAS9429_Spy0022 | -78 | 4.7 | AAAAACGAACCTT | |
| 14 | 4 | AAAGGCGAATAAT | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: purC | ||||
| Ortholog function: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1622 | -132 | 4.8 | ATTTCCGAACATT |
| -115 | 5.1 | AAAACCGAACAAT | ||
| Lactococcus lactis subsp. lactis Il1403 | L177350 | -132 | 4.8 | ATTTCCGAACATT |
| -115 | 5.1 | AAAACCGAACAAT | ||
| Streptococcus agalactiae 2603V/R | SAG0024 | -108 | 4.9 | AAATACGAACGTT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0043 | -106 | 5.2 | AAAAACGAACATT |
| -13 | 4.2 | AAAGACGAATATT | ||
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0023 | -110 | 5.2 | AAAAACGAACATT |
| -16 | 4.3 | AAAGGCGAACAAA | ||
| Streptococcus gallolyticus UCN34 | GALLO_0025 | -109 | 4.3 | AATTTCGAACGTT |
| -16 | 4.3 | AAAGGCGAACAAA | ||
| Streptococcus gordonii str. Challis substr. CH1 | SGO_0034 | -16 | 4.8 | AAAGGCGAACATT |
| Streptococcus mitis B6 | smi_0066 | 155 | 4.3 | AAAGGCGAACTTT |
| Streptococcus mutans UA159 | SMU.29 | -109 | 4.8 | AAATGCGAACGAT |
| -16 | 4.7 | AAAGGCGAACAAT | ||
| Streptococcus pneumoniae TIGR4 | SP_0044 | -16 | 4.3 | AAAGGCGAACTTT |
| Streptococcus pyogenes M1 GAS | SPy0024 | -78 | 4.7 | AAAAACGAACCTT |
| Streptococcus sanguinis SK36 | SSA_0028 | -16 | 4.1 | AAAGGCGAATATT |
| Streptococcus suis 05ZYH33 | SSU05_0026 | -16 | 4.8 | AAAGGCGAACATT |
| Streptococcus thermophilus CNRZ1066 | str0030 | -109 | 4.9 | AAATCCGAACGTT |
| -16 | 4.6 | AAAGGCGAACGAT | ||
| Streptococcus uberis 0140J | SUB0025 | -108 | 5.2 | AAAAACGAACATT |
| -15 | 4.7 | AAAGGCGAACAAT | ||
|
Position: -184
Score: 4.7 Sequence: AAAACCGAACTTT
Locus tag: MGAS9429_Spy0974
|
||||
| MGAS9429_Spy0974 | -184 | 4.7 | AAAACCGAACTTT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: guaC | ||||
| Ortholog function: GMP reductase (EC 1.7.1.7) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1256 | -232 | 4.7 | ATTTCCGAACGTT |
| Lactococcus lactis subsp. lactis Il1403 | L158186 | -227 | 3.9 | ATTTCCGAATGAT |
| Streptococcus agalactiae 2603V/R | SAG1087 | -149 | 5.2 | AAAAACGAACATT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_0894 | -205 | 5.2 | AAAACCGAACATT |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_1036 | -209 | 5 | AAAAACGAACGTT |
| Streptococcus gallolyticus UCN34 | GALLO_1025 | -260 | 5.2 | AAAAACGAACATT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1159 | -146 | 4.7 | ATTTCCGAACGTT |
| Streptococcus mitis B6 | smi_1212 | -141 | 4.9 | AAATCCGAACGAT |
| Streptococcus pneumoniae TIGR4 | SP_1249 | -141 | 4.6 | AAACCCGAACGAT |
| Streptococcus pyogenes M1 GAS | SPy1135 | -205 | 4.7 | AAAACCGAACTTT |
| Streptococcus suis 05ZYH33 | SSU05_0815 | -87 | 4.3 | AATTCTGAACATT |
| Streptococcus uberis 0140J | SUB0865 | -187 | 4.6 | AAATCCGAACAAA |
|
Position: -93
Score: 5.1 Sequence: AAAAACGAACAAT
Locus tag: MGAS9429_Spy1030
|
||||
| MGAS9429_Spy1030 | -93 | 5.1 | AAAAACGAACAAT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: fhs | ||||
| Ortholog function: Formate--tetrahydrofolate ligase (EC 6.3.4.3) | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1007 | -134 | 4.8 | ATTTCCGAACAAT |
| Lactococcus lactis subsp. lactis Il1403 | L159505 | -131 | 4.8 | ATTTCCGAACAAT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_1033 | -93 | 5.2 | AAAAACGAACATT |
| Streptococcus equi subsp. zooepidemicus MGCS10565 | Sez_0945 | -94 | 4.9 | AAAAGCGAACGTT |
| Streptococcus gallolyticus UCN34 | GALLO_1115 | -100 | 4.8 | AAACACGAACATT |
| Streptococcus gordonii str. Challis substr. CH1 | SGO_1210 | -95 | 4.8 | AAACACGAACAAT |
| Streptococcus mitis B6 | smi_1192 | -90 | 4.2 | TTTTACGAACGTT |
| Streptococcus mutans UA159 | SMU.1073 | -90 | 5.1 | AAATCCGAACATT |
| Streptococcus pneumoniae TIGR4 | SP_1229 | -172 | 4.6 | AAAAACGAAGATT |
| -89 | 4.7 | ATTTACGAACGTT | ||
| Streptococcus pyogenes M1 GAS | SPy1213 | -93 | 5.1 | AAAAACGAACAAT |
| Streptococcus sanguinis SK36 | SSA_1200 | -93 | 4.1 | TTTCCCGAACATT |
| Streptococcus suis 05ZYH33 | SSU05_0690 | -97 | 4.1 | AATTCCGTACGTT |
| Streptococcus thermophilus CNRZ1066 | str0791 | -94 | 5.2 | AAAACCGAACATT |
|
Position: -102
Score: 4.6 Sequence: TAATACGAACAAT
Locus tag: MGAS9429_Spy1479
|
||||
| MGAS9429_Spy1479 | -102 | 4.6 | TAATACGAACAAT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: pbuO | ||||
| Ortholog function: Guanine/hypoxanthine permease | ||||
| Lactococcus lactis subsp. cremoris SK11 | LACR_1894 | -184 | 4.7 | ATTACCGAACGAT |
| Lactococcus lactis subsp. lactis Il1403 | L171588 | -184 | 4.9 | ATTACCGAACAAT |
| Streptococcus dysgalactiae subsp. equisimilis GGS_124 | SDEG_1804 | -143 | 4.3 | AAATAAGAACAAT |
| -100 | 5 | AAATACGAACAAT | ||
| Streptococcus gallolyticus UCN34 | GALLO_0354 | -96 | 4.3 | AAAAGTGAACAAT |
| Streptococcus pyogenes M1 GAS | SPy1736 | -102 | 5 | AATACCGAACAAT |
| Streptococcus uberis 0140J | SUB1480 | -166 | 4.9 | AAAAGCGAACGTT |