Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of SczA regulog to Streptococcus pyogenes MGAS9429

Reference regulog properties
Source regulog: SczA - Streptococcaceae
Regulator type: Transcription factor
Regulator family: TetR
Regulation mode: repressor
Biological process: Zinc resistance
Effector: Zinc ion, (Zn2+)
Phylum: Firmicutes
Propagated regulon:
Target genome Streptococcus pyogenes MGAS9429
Orthologous TF(s) MGAS9429_Spy0709
Regulated genes 2
Built upon 18 sites [see more]
Predicted regulatory interactions in Streptococcus pyogenes MGAS9429
Locus tag Position Score Sequence
Position: -115
Score: 5.7
Sequence: TGTTCACTATTGAACA
Locus tag: MGAS9429_Spy0708
MGAS9429_Spy0708 -115 5.7 TGTTCACTATTGAACA
Supported by regulated orthologs from reference regulons
Ortholog gene name: czcD
Ortholog function: Cobalt-zinc-cadmium resistance protein CzcD
Streptococcus agalactiae 2603V/R SAG0430 -111 6.1 TGTTCAGTATTGAACA
Streptococcus pyogenes M1 GAS SPy0845 -115 5.7 TGTTCACTATTGAACA
Position: -27
Score: 5.7
Sequence: TGTTCAATAGTGAACA
Locus tag: MGAS9429_Spy0709
MGAS9429_Spy0709 -27 5.7 TGTTCAATAGTGAACA
Supported by regulated orthologs from reference regulons
Ortholog gene name: sczA
Ortholog function: Zinc stress response transcriptional regulator SczA, TetR family
Streptococcus agalactiae 2603V/R SAG0431 -36 6.1 TGTTCAATACTGAACA
Streptococcus gordonii str. Challis substr. CH1 SGO_0929 76 5.7 TGTACAGTTCTGAACA
Streptococcus mitis B6 smi_0517 -35 5.8 TATTCAGTTCTGAACA
Streptococcus pneumoniae TIGR4 SP_1858 -35 5.8 TATTCAGTTCTGAACA
Streptococcus pyogenes M1 GAS SPy0846 -36 5.7 TGTTCAATAGTGAACA
Streptococcus thermophilus CNRZ1066 str0931 -35 5.3 TGTACGTTACTGAACA