Regulon of UxaR in Thermotoga naphthophila RKU-10

Properties
Regulator type:	Transcription factor
TF locus tag:	Tnap_0221
Regulator family:	GntR/Others
Regulation mode:	repressor
Biological process:	Galacturonate utilization; Pectin utilization
Effector:
Regulog:	UxaR - Thermotogales
Statistics of regulated genes:
- Genes	16
- Operons	3
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 18 sites [see more]

Member of regulog collections

By taxonomy - Thermotogales
By TF family - GntR/Others
By pathway - Galacturonate utilization
By pathway - Pectin utilization

Regulated operons
	Locus Tag	Name	Function
Position: -35 Score: 6.3 Sequence: TGAAATATCACACATCT Locus tag: Tnap_0214 Name: uxaX Funciton: Predicted sugar ABC transporter, substrate binding protein Locus tag: Tnap_0215 Name: uxaY Funciton: Predicted sugar ABC transporter, permease protein Locus tag: Tnap_0216 Name: uxaZ Funciton: Predicted sugar ABC transporter, ATP-binding protein
	Tnap_0214	uxaX	Predicted sugar ABC transporter, substrate binding protein
	Tnap_0215	uxaY	Predicted sugar ABC transporter, permease protein
	Tnap_0216	uxaZ	Predicted sugar ABC transporter, ATP-binding protein
Position: -29 Score: 6.2 Sequence: TTAAACATCACATATCA Locus tag: Tnap_0696 Name: kdgA Funciton: 2-dehydro-3-deoxyphosphogluconate aldolase Locus tag: Tnap_0697 Name: kdgK Funciton: 2-keto-3-deoxygluconate kinase (EC 2.7.1.45) Locus tag: Tnap_0698 Name: uxuB Funciton: D-mannonate oxidoreductase (EC 1.1.1.57) Locus tag: Tnap_0699 Name: uxuA Funciton: Mannonate dehydratase (EC 4.2.1.8)
	Tnap_0696	kdgA	2-dehydro-3-deoxyphosphogluconate aldolase
	Tnap_0697	kdgK	2-keto-3-deoxygluconate kinase (EC 2.7.1.45)
	Tnap_0698	uxuB	D-mannonate oxidoreductase (EC 1.1.1.57)
	Tnap_0699	uxuA	Mannonate dehydratase (EC 4.2.1.8)
Position: -88 Score: 6.4 Sequence: TAAAACATCACATATCT Locus tag: Tnap_0217 Name: uxaP Funciton: Predicted galacturonate TRAP transporter, substrate binding subunit Locus tag: Tnap_0218 Name: uxaQ Funciton: Predicted galacturonate TRAP transporter, small permease subunit Locus tag: Tnap_0219 Name: uxaM Funciton: Predicted galacturonate TRAP transporter, large permease subunit Locus tag: Tnap_0220 Name: gnd Funciton: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44) Locus tag: Tnap_0221 Name: uxaR Funciton: Regulator of pectin and galacturonate utilization, GntR family Locus tag: Tnap_0222 Name: uxaE Funciton: D-tagaturonate epimerase Locus tag: Tnap_0223 Name: uxuB2 Funciton: D-mannonate dehydrogenase (EC 1.1.1.57), NADPH-dependent Locus tag: Tnap_0224 Name: gntE Funciton: novel D-mannonate-D-gluconate epimerase Locus tag: Tnap_0225 Name: gntK Funciton: Gluconokinase (EC 2.7.1.12)
	Tnap_0217	uxaP	Predicted galacturonate TRAP transporter, substrate binding subunit
	Tnap_0218	uxaQ	Predicted galacturonate TRAP transporter, small permease subunit
	Tnap_0219	uxaM	Predicted galacturonate TRAP transporter, large permease subunit
	Tnap_0220	gnd	6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)
	Tnap_0221	uxaR	Regulator of pectin and galacturonate utilization, GntR family
	Tnap_0222	uxaE	D-tagaturonate epimerase
	Tnap_0223	uxuB2	D-mannonate dehydrogenase (EC 1.1.1.57), NADPH-dependent
	Tnap_0224	gntE	novel D-mannonate-D-gluconate epimerase
	Tnap_0225	gntK	Gluconokinase (EC 2.7.1.12)

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