Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of UxaR in Thermotoga maritima MSB8

Properties
Regulator type: Transcription factor
TF locus tag: TM0439
Regulator family: GntR/Others
Regulation mode: repressor
Biological process: Galacturonate utilization; Pectin utilization
Effector:
Regulog: UxaR - Thermotogales
Statistics of regulated genes:
- Genes 16
- Operons 4
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 18 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -29
Score: 6.4
Sequence: TGAAACATCAGATATCT
Locus tag: TM0433
Name: pelA
Funciton: Pectate lyase precursor (EC 4.2.2.2)
pelA
Pectate lyase precursor (EC 4.2.2.2)

Position: -50
Score: 5.4
Sequence: TGAAGTATCAGACATCA
Locus tag: TM0432
Name: aguE
Funciton: Alpha-1,4-digalacturonate ABC transporter, substrate binding protein
Locus tag: TM0431
Name: aguF
Funciton: Alpha-1,4-digalacturonate ABC transporter, permease protein 1
Locus tag: TM0430
Name: aguG
Funciton: Alpha-1,4-digalacturonate ABC transporter, permease protein 2
aguE
Alpha-1,4-digalacturonate ABC transporter, substrate binding protein
aguF
Alpha-1,4-digalacturonate ABC transporter, permease protein 1
aguG
Alpha-1,4-digalacturonate ABC transporter, permease protein 2

Position: -23
Score: 6
Sequence: TTAAATATCACATATCA
Locus tag: TM0066
Name: kdgA
Funciton: 2-dehydro-3-deoxyphosphogluconate aldolase
Locus tag: TM0067
Name: kdgK
Funciton: 2-keto-3-deoxygluconate kinase (EC 2.7.1.45)
Locus tag: TM0068
Name: uxuB
Funciton: D-mannonate oxidoreductase (EC 1.1.1.57)
Locus tag: TM0069
Name: uxuA
Funciton: Mannonate dehydratase (EC 4.2.1.8)
kdgA
2-dehydro-3-deoxyphosphogluconate aldolase
kdgK
2-keto-3-deoxygluconate kinase (EC 2.7.1.45)
uxuB
D-mannonate oxidoreductase (EC 1.1.1.57)
uxuA
Mannonate dehydratase (EC 4.2.1.8)

Position: -25
Score: 6.4
Sequence: TGAAACATCAAACATCT
Locus tag: TM0436
Name: aldH
Funciton: alcohol dehydrogenase, zinc-containing
Locus tag: TM0437
Name: pelB
Funciton: Polygalacturonase (EC 3.2.1.15)
Locus tag: TM0438
Name: gnd
Funciton: 6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)
Locus tag: TM0439
Name: uxaR
Funciton: Regulator of pectin and galacturonate utilization, GntR family
Locus tag: TM0440
Name: uxaE
Funciton: D-tagaturonate epimerase
Locus tag: TM0441
Name: uxuB2
Funciton: D-mannonate dehydrogenase (EC 1.1.1.57), NADPH-dependent
Locus tag: TM0442
Name: gntE
Funciton: novel D-mannonate-D-gluconate epimerase
Locus tag: TM0443
Name: gntK
Funciton: Gluconokinase (EC 2.7.1.12)
aldH
alcohol dehydrogenase, zinc-containing
pelB
Polygalacturonase (EC 3.2.1.15)
gnd
6-phosphogluconate dehydrogenase, decarboxylating (EC 1.1.1.44)
uxaR
Regulator of pectin and galacturonate utilization, GntR family
uxaE
D-tagaturonate epimerase
uxuB2
D-mannonate dehydrogenase (EC 1.1.1.57), NADPH-dependent
gntE
novel D-mannonate-D-gluconate epimerase
gntK
Gluconokinase (EC 2.7.1.12)
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