Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of TyrR in Shewanella pealeana ATCC 700345

Properties
Regulator type: Transcription factor
TF locus tag: Spea_1450
Regulator family: TyrR
Regulation mode: activator
Biological process: Amino acid utilization
Effector: Tyrosine; Phenylalanine
Regulog: TyrR - Shewanellaceae
Statistics of regulated genes:
- Genes 34
- Operons 16
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 312 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -157
Score: 4.9
Sequence: GTGGAAAGCAAAATTGCCAG
Locus tag: Spea_2543
Name: ldh
Funciton: Leucine dehydrogenase (EC 1.4.1.9)
ldh
Leucine dehydrogenase (EC 1.4.1.9)

Position: -90
Score: 5.2
Sequence: GTGTAAAGTAATAATTACAC
Locus tag: Spea_0804
Name: brnQ
Funciton: Branched-chain amino acid transport system carrier protein
brnQ
Branched-chain amino acid transport system carrier protein

Position: -290
Score: 4.2
Sequence: CCGGAAATTTTTAGTTCCAC
Locus tag: Spea_2071
Name: aroA
Funciton: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)
aroA
5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)

Position: -197
Score: 4.8
Sequence: GTGTATCTATAAGTTTACAC
Locus tag: Spea_1451
Name: hmgC
Funciton: Fumarylacetoacetase (EC 3.7.1.2)
Locus tag: Spea_1452
Name: hmgB
Funciton: Maleylacetoacetate isomerase (EC 5.2.1.2)
hmgC
Fumarylacetoacetase (EC 3.7.1.2)
hmgB
Maleylacetoacetate isomerase (EC 5.2.1.2)

Position: -141
Score: 4.5
Sequence: GTGGAAACTTTGGCTGACAA
Locus tag: Spea_3091
Name: pepD
Funciton: Aminoacyl-histidine dipeptidase (Peptidase D) (EC 3.4.13.3)
pepD
Aminoacyl-histidine dipeptidase (Peptidase D) (EC 3.4.13.3)

Position: -111
Score: 4.4
Sequence: GTGGCAAGCGCAATTGACAT
Locus tag: Spea_2796
Name: liuR
Funciton: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
Locus tag: Spea_2797
Name: liuA
Funciton: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
Locus tag: Spea_2798
Name: liuB
Funciton: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
Locus tag: Spea_2799
Name: liuC
Funciton: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
Locus tag: Spea_2800
Name: liuD
Funciton: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
Locus tag: Spea_2802
Name: liuE
Funciton: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
Locus tag: Spea_2803
Name: liuF
Funciton: Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5)
Locus tag: Spea_2804
Name: liuG
Funciton: Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5)
liuR
Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
liuA
Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
liuB
Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
liuC
Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
liuD
Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
liuE
Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
liuF
Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5)
liuG
Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5)

Position: -158
Score: 4.6
Sequence: CTGTAAACAAGTCTTGCCAC
Locus tag: Spea_1450
Name: tyrR
Funciton: Transcriptional regulator of aromatic amino acid biosynthesis
tyrR
Transcriptional regulator of aromatic amino acid biosynthesis

Position: -111
Score: 4.5
Sequence: TTGTCAGCCAAAGTTTCCAC
Locus tag: Spea_3090
Name: SO1117
Funciton: peptidase M17, leucyl aminopeptidase
SO1117
peptidase M17, leucyl aminopeptidase

Position: -106
Score: 3.9
Sequence: AAGTAAAGCAAGCTTGACTT
Position: -62
Score: 4.2
Sequence: AAGTCAAGCGTGCTTTACAT
Locus tag: Spea_0139
Name: Sfri_3409
Funciton: hypothetical protein
Locus tag: Spea_0138
Name: Sfri_3410
Funciton: transcriptional regulator, XRE family protein
Sfri_3409
hypothetical protein
Sfri_3410
transcriptional regulator, XRE family protein

Position: -215
Score: 4
Sequence: ACGTAACAATCACTTTACAA
Locus tag: Spea_2664
Name: mdeA
Funciton: Methionine gamma-lyase (EC 4.4.1.11)
mdeA
Methionine gamma-lyase (EC 4.4.1.11)

Position: -237
Score: 3.8
Sequence: TGGGAAACCTTTTCTTACAC
Locus tag: Spea_3177
Name: pep3
Funciton: peptidase, M13 family
pep3
peptidase, M13 family

Position: -231
Score: 4.5
Sequence: GTGTAAATTCTATGTGACAA
Locus tag: Spea_2783
Name: ivdA
Funciton: 3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16)
Locus tag: Spea_2782
Name: ivdB
Funciton: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
Locus tag: Spea_2781
Name: ivdC
Funciton: Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
Locus tag: Spea_2780
Name: ivdD
Funciton: Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) / Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17)
Locus tag: Spea_2779
Name: ivdE
Funciton: 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
Locus tag: Spea_2778
Name: ivdF
Funciton: 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
Locus tag: Spea_2777
Name: ivdG
Funciton: 3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)
ivdA
3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16)
ivdB
Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
ivdC
Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
ivdD
Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) / Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17)
ivdE
3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
ivdF
3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
ivdG
3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)

Position: -239
Score: 4.3
Sequence: GTGTCAATTTCTATATACGC
Position: -173
Score: 4.8
Sequence: GTGTAACATTAGCATTACAC
Locus tag: Spea_1448
Name: phhA
Funciton: Phenylalanine-4-hydroxylase (EC 1.14.16.1)
Locus tag: Spea_1449
Name: phhB
Funciton: Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96)
phhA
Phenylalanine-4-hydroxylase (EC 1.14.16.1)
phhB
Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96)

Position: -415
Score: 3.9
Sequence: GTGGCAATAATTGTTAACGA
Locus tag: Spea_1290
Name: aceB
Funciton: Malate synthase (EC 2.3.3.9)
aceB
Malate synthase (EC 2.3.3.9)

Position: -161
Score: 4.8
Sequence: ATGTAAACCAATATATACAT
Locus tag: Spea_2246
Name: bkdA1
Funciton: Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)
Locus tag: Spea_2245
Name: bkdA2
Funciton: Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)
Locus tag: Spea_2244
Name: bkdB
Funciton: Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
bkdA1
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)
bkdA2
Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)
bkdB
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)

Position: -138
Score: 4.2
Sequence: GTGGAACTAAAAATTTCCGG
Locus tag: Spea_2070
Name: tyrB
Funciton: Tyrosine aminotransferase (EC 2.6.1.42)
tyrB
Tyrosine aminotransferase (EC 2.6.1.42)
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