Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of TyrR in Shewanella loihica PV-4

Properties
Regulator type: Transcription factor
TF locus tag: Shew_1437
Regulator family: TyrR
Regulation mode: activator
Biological process: Amino acid utilization
Effector: Tyrosine; Phenylalanine
Regulog: TyrR - Shewanellaceae
Statistics of regulated genes:
- Genes 27
- Operons 15
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 312 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -157
Score: 5.1
Sequence: GTGGAAAGCAAAATTGCCAC
Locus tag: Shew_1555
Name: ldh
Funciton: Leucine dehydrogenase (EC 1.4.1.9)
ldh
Leucine dehydrogenase (EC 1.4.1.9)

Position: -268
Score: 4
Sequence: TTGGCAAATTTTCATGCCAG
Locus tag: Shew_1952
Name: aroA
Funciton: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)
aroA
5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)

Position: -123
Score: 4.6
Sequence: GTGGCAACTTAGTATGACAC
Locus tag: Shew_2852
Name: pepD
Funciton: Aminoacyl-histidine dipeptidase (Peptidase D) (EC 3.4.13.3)
pepD
Aminoacyl-histidine dipeptidase (Peptidase D) (EC 3.4.13.3)

Position: -162
Score: 4.7
Sequence: GTGTAAACAACTCTTGCCAC
Locus tag: Shew_1437
Name: tyrR
Funciton: Transcriptional regulator of aromatic amino acid biosynthesis
tyrR
Transcriptional regulator of aromatic amino acid biosynthesis

Position: -102
Score: 4.6
Sequence: GTGTAATAAGAAGTTTACAC
Locus tag: Shew_0769
Name: brnQ
Funciton: Branched-chain amino acid transport system carrier protein
brnQ
Branched-chain amino acid transport system carrier protein

Position: -320
Score: 4.6
Sequence: GTGTCATACTAAGTTGCCAC
Locus tag: Shew_2851
Name: SO1117
Funciton: peptidase M17, leucyl aminopeptidase
SO1117
peptidase M17, leucyl aminopeptidase

Position: -169
Score: 4.5
Sequence: CTGTCATGAATTGTTTACAA
Locus tag: Shew_1438
Name: hmgC
Funciton: Fumarylacetoacetase (EC 3.7.1.2)
Locus tag: Shew_1439
Name: hmgB
Funciton: Maleylacetoacetate isomerase (EC 5.2.1.2)
hmgC
Fumarylacetoacetase (EC 3.7.1.2)
hmgB
Maleylacetoacetate isomerase (EC 5.2.1.2)

Position: -90
Score: 4.4
Sequence: ATGTAAAGCATGCTTGACCT
Position: -45
Score: 4.1
Sequence: ATGTAAAGGGTGTTTGACAT
Locus tag: Shew_3626
Name: Sfri_3409
Funciton: hypothetical protein
Locus tag: Shew_3627
Name: Sfri_3410
Funciton: transcriptional regulator, XRE family protein
Sfri_3409
hypothetical protein
Sfri_3410
transcriptional regulator, XRE family protein

Position: -134
Score: 4.1
Sequence: CTGTAACGATATCTTGTCAC
Locus tag: Shew_3635
Name: ipdC
Funciton: Indole-3-pyruvate decarboxylase (EC 4.1.1.74)
ipdC
Indole-3-pyruvate decarboxylase (EC 4.1.1.74)

Position: -180
Score: 4.1
Sequence: GAGGAAATCTTTACTTACAT
Locus tag: Shew_2973
Name: pep3
Funciton: peptidase, M13 family
pep3
peptidase, M13 family

Position: -168
Score: 4.4
Sequence: CTGTAAATTCAGCCTGACAA
Locus tag: Shew_1667
Name: ivdA
Funciton: 3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16)
Locus tag: Shew_1668
Name: ivdB
Funciton: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
Locus tag: Shew_1669
Name: ivdC
Funciton: Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
Locus tag: Shew_1670
Name: ivdD
Funciton: Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) / Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17)
Locus tag: Shew_1671
Name: ivdE
Funciton: 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
Locus tag: Shew_1672
Name: ivdF
Funciton: 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
Locus tag: Shew_1673
Name: ivdG
Funciton: 3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)
ivdA
3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16)
ivdB
Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
ivdC
Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
ivdD
Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) / Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17)
ivdE
3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
ivdF
3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
ivdG
3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)

Position: -87
Score: 4.7
Sequence: ATGTAAATTTGAGGTTACAT
Locus tag: Shew_1435
Name: phhA
Funciton: Phenylalanine-4-hydroxylase (EC 1.14.16.1)
Locus tag: Shew_1436
Name: phhB
Funciton: Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96)
phhA
Phenylalanine-4-hydroxylase (EC 1.14.16.1)
phhB
Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96)

Position: -393
Score: 3.4
Sequence: CTGTATCGACAAAATTACTA
Locus tag: Shew_1275
Name: aceB
Funciton: Malate synthase (EC 2.3.3.9)
Locus tag: Shew_1276
Name: aceA
Funciton: Isocitrate lyase (EC 4.1.3.1)
aceB
Malate synthase (EC 2.3.3.9)
aceA
Isocitrate lyase (EC 4.1.3.1)

Position: -175
Score: 4.7
Sequence: TTGTAAAGCTAGCGATACAT
Locus tag: Shew_1925
Name: bkdA1
Funciton: Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)
Locus tag: Shew_1926
Name: bkdA2
Funciton: Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)
Locus tag: Shew_1927
Name: bkdB
Funciton: Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
bkdA1
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)
bkdA2
Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)
bkdB
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)

Position: -141
Score: 4
Sequence: CTGGCATGAAAATTTGCCAA
Locus tag: Shew_1951
Name: tyrB
Funciton: Tyrosine aminotransferase (EC 2.6.1.42)
tyrB
Tyrosine aminotransferase (EC 2.6.1.42)
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