Regulon of TyrR in Shewanella sp MR-7

Properties
Regulator type:	Transcription factor
TF locus tag:	Shewmr7_2672
Regulator family:	TyrR
Regulation mode:	activator
Biological process:	Amino acid utilization
Effector:	Tyrosine; Phenylalanine
Regulog:	TyrR - Shewanellaceae
Statistics of regulated genes:
- Genes	37
- Operons	18
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 312 sites [see more]

Member of regulog collections

By taxonomy - Shewanellaceae
By trascription factor - TyrR
By TF family - TyrR
By effector - Tyrosine
By effector - Phenylalanine
By pathway - Amino acid utilization

Regulated operons
	Locus Tag	Name	Function
Position: -180 Score: 4.5 Sequence: GTGTAAATAAAAAGTGGCAT Locus tag: Shewmr7_3725 Name: tdo Funciton: tryptophan 2,3-dioxygenase Locus tag: Shewmr7_3724 Name: kyn Funciton: kynureninase (tryptophan degradation)
	Shewmr7_3725	tdo	tryptophan 2,3-dioxygenase
	Shewmr7_3724	kyn	kynureninase (tryptophan degradation)
Position: -218 Score: 4 Sequence: GTGGCAATTAATTTTACCAG Position: -152 Score: 4.6 Sequence: GTGTAAGCTAAATTTTACAG Locus tag: Shewmr7_2040 Name: emrD Funciton: multidrug resistance protein D
	Shewmr7_2040	emrD	multidrug resistance protein D
Position: -172 Score: 4.2 Sequence: ATGGTAATTTTTAGTTACAA Locus tag: Shewmr7_0787 Name: pep3 Funciton: peptidase, M13 family
	Shewmr7_0787	pep3	peptidase, M13 family
Position: -298 Score: 3.9 Sequence: CTGGCAAAAAAGCCTGCCAA Position: -101 Score: 4.5 Sequence: TTGTAATCTTAACTTGACGC Locus tag: Shewmr7_2056 Name: aroA Funciton: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)
	Shewmr7_2056	aroA	5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)
Position: -319 Score: 3.8 Sequence: ATGTAACAGTATCGTTCCAC Position: -235 Score: 4.4 Sequence: ACGTAATGATTAGTTTACAA Locus tag: Shewmr7_2671 Name: hmgC Funciton: Fumarylacetoacetase (EC 3.7.1.2) Locus tag: Shewmr7_2670 Name: hmgB Funciton: Maleylacetoacetate isomerase (EC 5.2.1.2)
	Shewmr7_2671	hmgC	Fumarylacetoacetase (EC 3.7.1.2)
	Shewmr7_2670	hmgB	Maleylacetoacetate isomerase (EC 5.2.1.2)
Position: -106 Score: 5.1 Sequence: GTGTAAACATAGATTTGCAC Locus tag: Shewmr7_3229 Name: brnQ Funciton: Branched-chain amino acid transport system carrier protein
	Shewmr7_3229	brnQ	Branched-chain amino acid transport system carrier protein
Position: -105 Score: 4.6 Sequence: GTGGCAACAAGAATTGACAA Locus tag: Shewmr7_2393 Name: liuR Funciton: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family Locus tag: Shewmr7_2394 Name: liuA Funciton: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10) Locus tag: Shewmr7_2395 Name: liuB Funciton: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4) Locus tag: Shewmr7_2396 Name: liuC Funciton: Methylglutaconyl-CoA hydratase (EC 4.2.1.18) Locus tag: Shewmr7_2397 Name: liuD Funciton: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4) Locus tag: Shewmr7_2398 Name: liuE Funciton: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) Locus tag: Shewmr7_2399 Name: liuF Funciton: Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5) Locus tag: Shewmr7_2400 Name: liuG Funciton: Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5)
	Shewmr7_2393	liuR	Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
	Shewmr7_2394	liuA	Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
	Shewmr7_2395	liuB	Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
	Shewmr7_2396	liuC	Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
	Shewmr7_2397	liuD	Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
	Shewmr7_2398	liuE	Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
	Shewmr7_2399	liuF	Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5)
	Shewmr7_2400	liuG	Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5)
Position: -197 Score: 4.6 Sequence: TTGTCAATTGAGCGTTACAT Locus tag: Shewmr7_0850 Name: putA Funciton: Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)
	Shewmr7_0850	putA	Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)
Position: -205 Score: 4.7 Sequence: CTGTAAACTAGACTTGCCAC Locus tag: Shewmr7_2672 Name: tyrR Funciton: Transcriptional regulator of aromatic amino acid biosynthesis
	Shewmr7_2672	tyrR	Transcriptional regulator of aromatic amino acid biosynthesis
Position: -372 Score: 3.8 Sequence: CTGTACATTTAAATTTTCAG Locus tag: Shewmr7_2845 Name: aceB Funciton: Malate synthase (EC 2.3.3.9) Locus tag: Shewmr7_2844 Name: aceA Funciton: Isocitrate lyase (EC 4.1.3.1)
	Shewmr7_2845	aceB	Malate synthase (EC 2.3.3.9)
	Shewmr7_2844	aceA	Isocitrate lyase (EC 4.1.3.1)
Position: -189 Score: 4.6 Sequence: TTGTCATTCTTTGTTTACAG Locus tag: Shewmr7_2637 Name: aprE2 Funciton: Cold-active alkaline serine protease (EC 3.4.21.62)
	Shewmr7_2637	aprE2	Cold-active alkaline serine protease (EC 3.4.21.62)
Position: -154 Score: 5.2 Sequence: GTGGAAAGCTAGATTGCCAC Locus tag: Shewmr7_1673 Name: ldh Funciton: Leucine dehydrogenase (EC 1.4.1.9)
	Shewmr7_1673	ldh	Leucine dehydrogenase (EC 1.4.1.9)
Position: -357 Score: 3.9 Sequence: TTTGAAATTAATCATTCCAA Locus tag: Shewmr7_1455 Name: aprE Funciton: Alkaline serine protease
	Shewmr7_1455	aprE	Alkaline serine protease
Position: -208 Score: 3.9 Sequence: ATGTAACAACTTAGTTACAG Locus tag: Shewmr7_2545 Name: mdeA Funciton: Methionine gamma-lyase (EC 4.4.1.11)
	Shewmr7_2545	mdeA	Methionine gamma-lyase (EC 4.4.1.11)
Position: -122 Score: 4.4 Sequence: TTGTAATATTTGCTTTACGT Locus tag: Shewmr7_2674 Name: phhA Funciton: Phenylalanine-4-hydroxylase (EC 1.14.16.1) Locus tag: Shewmr7_2673 Name: phhB Funciton: Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96)
	Shewmr7_2674	phhA	Phenylalanine-4-hydroxylase (EC 1.14.16.1)
	Shewmr7_2673	phhB	Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96)
Position: -159 Score: 4.4 Sequence: CTGTAAATCCTGACTGACAA Locus tag: Shewmr7_2664 Name: ivdA Funciton: 3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16) Locus tag: Shewmr7_2663 Name: ivdB Funciton: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) Locus tag: Shewmr7_2662 Name: ivdC Funciton: Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12) Locus tag: Shewmr7_2661 Name: ivdD Funciton: Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) / Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17) Locus tag: Shewmr7_2660 Name: ivdE Funciton: 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4) Locus tag: Shewmr7_2659 Name: ivdF Funciton: 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) Locus tag: Shewmr7_2658 Name: ivdG Funciton: 3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)
	Shewmr7_2664	ivdA	3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16)
	Shewmr7_2663	ivdB	Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
	Shewmr7_2662	ivdC	Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
	Shewmr7_2661	ivdD	Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) / Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17)
	Shewmr7_2660	ivdE	3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
	Shewmr7_2659	ivdF	3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
	Shewmr7_2658	ivdG	3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)
Position: -160 Score: 4.8 Sequence: TTGTAAAGCATTATATACAT Locus tag: Shewmr7_1947 Name: bkdA1 Funciton: Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4) Locus tag: Shewmr7_1948 Name: bkdA2 Funciton: Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4) Locus tag: Shewmr7_1949 Name: bkdB Funciton: Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
	Shewmr7_1947	bkdA1	Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)
	Shewmr7_1948	bkdA2	Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)
	Shewmr7_1949	bkdB	Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
Position: -155 Score: 3.9 Sequence: TTGGCAGGCTTTTTTGCCAG Locus tag: Shewmr7_2057 Name: tyrB Funciton: Tyrosine aminotransferase (EC 2.6.1.42)
	Shewmr7_2057	tyrB	Tyrosine aminotransferase (EC 2.6.1.42)

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of TyrR in Shewanella sp MR-7

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --