Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of TyrR in Shewanella oneidensis MR-1

Properties
Regulator type: Transcription factor
TF locus tag: SO_1669
Regulator family: TyrR
Regulation mode: activator
Biological process: Amino acid utilization
Effector: Tyrosine; Phenylalanine
Regulog: TyrR - Shewanellaceae
Statistics of regulated genes:
- Genes 36
- Operons 17
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 312 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -212
Score: 4.8
Sequence: TTGTCAATCAAGCGTTACAT
Locus tag: SO_3774
Name: putA
Funciton: Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)
putA
Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase) / Delta-1-pyrroline-5-carboxylate dehydrogenase (EC 1.5.1.12)

Position: -152
Score: 4.5
Sequence: ATGTAAGCTTAATTTTACAG
Locus tag: SO_2389
Name: emrD
Funciton: multidrug resistance protein D
emrD
multidrug resistance protein D

Position: -105
Score: 4.6
Sequence: GTGGCAACAAGAATTGACAA
Locus tag: SO_1898
Name: liuR
Funciton: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
Locus tag: SO_1897
Name: liuA
Funciton: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
Locus tag: SO_1896
Name: liuB
Funciton: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
Locus tag: SO_1895
Name: liuC
Funciton: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
Locus tag: SO_1894
Name: liuD
Funciton: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
Locus tag: SO_1893
Name: liuE
Funciton: Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
Locus tag: SO_1892
Name: liuF
Funciton: Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5)
Locus tag: SO_1891
Name: liuG
Funciton: Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5)
liuR
Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
liuA
Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
liuB
Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
liuC
Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
liuD
Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
liuE
Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4)
liuF
Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A (EC 2.8.3.5)
liuG
Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B (EC 2.8.3.5)

Position: -190
Score: 4.7
Sequence: CTGTAAACTAGGCTTGCCAC
Locus tag: SO_1669
Name: tyrR
Funciton: Transcriptional regulator of aromatic amino acid biosynthesis
tyrR
Transcriptional regulator of aromatic amino acid biosynthesis

Position: -121
Score: 5
Sequence: GTGTAAACATAGGTTTGCAC
Locus tag: SO_0949
Name: brnQ
Funciton: Branched-chain amino acid transport system carrier protein
brnQ
Branched-chain amino acid transport system carrier protein

Position: -101
Score: 3.8
Sequence: TAGTAACGTAAACTTGACGT
Position: -80
Score: 3.6
Sequence: ATGTAGTGTGAAGTTGCCAT
Locus tag: SO_2404
Name: aroA
Funciton: 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)
aroA
5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)

Position: -147
Score: 4.3
Sequence: GTGTAAATCCTAATTGAGAA
Locus tag: SO_4699
Name: prlC
Funciton: Oligopeptidase A (EC 3.4.24.70)
prlC
Oligopeptidase A (EC 3.4.24.70)

Position: -323
Score: 3.8
Sequence: ATGTAACAGTATCGTTCCAC
Position: -239
Score: 4.3
Sequence: ACGTAATGATTAGTTTACAG
Locus tag: SO_1670
Name: hmgC
Funciton: Fumarylacetoacetase (EC 3.7.1.2)
Locus tag: SO_1671
Name: hmgB
Funciton: Maleylacetoacetate isomerase (EC 5.2.1.2)
hmgC
Fumarylacetoacetase (EC 3.7.1.2)
hmgB
Maleylacetoacetate isomerase (EC 5.2.1.2)

Position: -175
Score: 4.5
Sequence: GTGTAAATAAAAAGTGGCAT
Locus tag: SO_4414
Name: tdo
Funciton: tryptophan 2,3-dioxygenase
Locus tag: SO_4413
Name: kyn
Funciton: kynureninase (tryptophan degradation)
tdo
tryptophan 2,3-dioxygenase
kyn
kynureninase (tryptophan degradation)

Position: -197
Score: 3.9
Sequence: ATGTAACAACTTAGTTACAG
Locus tag: SO_1812
Name: mdeA
Funciton: Methionine gamma-lyase (EC 4.4.1.11)
mdeA
Methionine gamma-lyase (EC 4.4.1.11)

Position: -173
Score: 4.2
Sequence: ATGGTAATTTTTAGTTACAA
Locus tag: SO_3844
Name: pep3
Funciton: peptidase, M13 family
pep3
peptidase, M13 family

Position: -159
Score: 4.4
Sequence: CTGTAAATCCTGACTGACAA
Locus tag: SO_1677
Name: ivdA
Funciton: 3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16)
Locus tag: SO_1678
Name: ivdB
Funciton: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
Locus tag: SO_1679
Name: ivdC
Funciton: Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
Locus tag: SO_1680
Name: ivdD
Funciton: Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) / Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17)
Locus tag: SO_1681
Name: ivdE
Funciton: 3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
Locus tag: SO_1682
Name: ivdF
Funciton: 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
Locus tag: SO_1683
Name: ivdG
Funciton: 3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)
ivdA
3-ketoacyl-CoA thiolase [isoleucine degradation] (EC 2.3.1.16)
ivdB
Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)
ivdC
Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12)
ivdD
Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) / Enoyl-CoA hydratase [isoleucine degradation] (EC 4.2.1.17)
ivdE
3-hydroxyisobutyryl-CoA hydrolase (EC 3.1.2.4)
ivdF
3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31)
ivdG
3-hydroxyacyl-CoA dehydrogenase [isoleucine degradation] (EC 1.1.1.35)

Position: -122
Score: 4.4
Sequence: TTGTAATATTTGCTTTACGT
Locus tag: SO_1666
Name: phhA
Funciton: Phenylalanine-4-hydroxylase (EC 1.14.16.1)
Locus tag: SO_1667
Name: phhB
Funciton: Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96)
phhA
Phenylalanine-4-hydroxylase (EC 1.14.16.1)
phhB
Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96)

Position: -372
Score: 3.7
Sequence: GTGTAATCATTGTTTTTCGA
Locus tag: SO_1483
Name: aceB
Funciton: Malate synthase (EC 2.3.3.9)
Locus tag: SO_1484
Name: aceA
Funciton: Isocitrate lyase (EC 4.1.3.1)
aceB
Malate synthase (EC 2.3.3.9)
aceA
Isocitrate lyase (EC 4.1.3.1)

Position: -160
Score: 4.9
Sequence: TTGTAAAGCAATATATACAT
Locus tag: SO_2339
Name: bkdA1
Funciton: Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)
Locus tag: SO_2340
Name: bkdA2
Funciton: Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)
Locus tag: SO_2341
Name: bkdB
Funciton: Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
bkdA1
Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)
bkdA2
Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)
bkdB
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)

Position: -154
Score: 5.2
Sequence: GTGGAAAGCTAGATTGCCAC
Locus tag: SO_2638
Name: ldh
Funciton: Leucine dehydrogenase (EC 1.4.1.9)
ldh
Leucine dehydrogenase (EC 1.4.1.9)

Position: -155
Score: 3.5
Sequence: TCGGCAGGCTTTTTTGCCAG
Locus tag: SO2406
Name: tyrB
Funciton: Tyrosine aminotransferase (EC 2.6.1.42)
tyrB
Tyrosine aminotransferase (EC 2.6.1.42)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD