Regulon of Rex in Streptomyces avermitilis MA-4680

Properties
Regulator type:	Transcription factor
TF locus tag:	SAV_4738
Regulator family:	Rex
Regulation mode:	repressor
Biological process:	Energy metabolism
Effector:	NADH
Regulog:	Rex - Streptomycetaceae
Statistics of regulated genes:
- Genes	39
- Operons	9
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 36 sites [see more]

Member of regulog collections

By taxonomy - Streptomycetaceae
By trascription factor - Rex
By TF family - Rex
By effector - NADH
By pathway - Energy metabolism

Regulated operons
	Locus Tag	Name	Function
Position: -60 Score: 5.5 Sequence: TCGTGAAAGCGTTCACAT Locus tag: SAV_3016 Name: whiE Funciton: WhiB-family transcriptional regulator involved in differentiation and sporulation
	SAV_3016	whiE	WhiB-family transcriptional regulator involved in differentiation and sporulation
Position: -94 Score: 6 Sequence: TTGTGCACGCGTTCACAA Locus tag: SAV_4738 Name: rex Funciton: Redox-sensitive transcriptional regulator Rex Locus tag: SAV_4739 Name: hemA Funciton: Glutamyl-tRNA reductase (EC 1.2.1.70) Locus tag: SAV_4740 Name: hemC Funciton: Porphobilinogen deaminase (EC 2.5.1.61) Locus tag: SAV_4741 Name: hemD Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
	SAV_4738	rex	Redox-sensitive transcriptional regulator Rex
	SAV_4739	hemA	Glutamyl-tRNA reductase (EC 1.2.1.70)
	SAV_4740	hemC	Porphobilinogen deaminase (EC 2.5.1.61)
	SAV_4741	hemD	Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
Position: -212 Score: 5 Sequence: TCGTGAATTGATTCACGA Locus tag: SAV_4616 Name: hppA Funciton: Pyrophosphate-energized proton pump (EC 3.6.1.1)
	SAV_4616	hppA	Pyrophosphate-energized proton pump (EC 3.6.1.1)
Position: -136 Score: 5.2 Sequence: TTGTGAAGGGGCGCACGA Locus tag: SAV_3529 Name: ndh Funciton: NADH dehydrogenase (EC 1.6.99.3)
	SAV_3529	ndh	NADH dehydrogenase (EC 1.6.99.3)
Position: -154 Score: 5.1 Sequence: TTGTGATACGGTTCACGA Locus tag: SAV_2888 Name: atpI Funciton: ATP synthase protein I Locus tag: SAV_2887 Name: atpB Funciton: ATP synthase A chain (EC 3.6.3.14) Locus tag: SAV_2886 Name: atpE Funciton: ATP synthase C chain (EC 3.6.3.14) Locus tag: SAV_2885 Name: atpF Funciton: ATP synthase B chain (EC 3.6.3.14) Locus tag: SAV_2884 Name: atpH Funciton: ATP synthase delta chain (EC 3.6.3.14) Locus tag: SAV_2883 Name: atpA Funciton: ATP synthase alpha chain (EC 3.6.3.14) Locus tag: SAV_2882 Name: atpG Funciton: ATP synthase gamma chain (EC 3.6.3.14) Locus tag: SAV_2881 Name: atpD Funciton: ATP synthase beta chain (EC 3.6.3.14) Locus tag: SAV_2880 Name: atpC Funciton: ATP synthase epsilon chain (EC 3.6.3.14)
	SAV_2888	atpI	ATP synthase protein I
	SAV_2887	atpB	ATP synthase A chain (EC 3.6.3.14)
	SAV_2886	atpE	ATP synthase C chain (EC 3.6.3.14)
	SAV_2885	atpF	ATP synthase B chain (EC 3.6.3.14)
	SAV_2884	atpH	ATP synthase delta chain (EC 3.6.3.14)
	SAV_2883	atpA	ATP synthase alpha chain (EC 3.6.3.14)
	SAV_2882	atpG	ATP synthase gamma chain (EC 3.6.3.14)
	SAV_2881	atpD	ATP synthase beta chain (EC 3.6.3.14)
	SAV_2880	atpC	ATP synthase epsilon chain (EC 3.6.3.14)
Position: -164 Score: 5.4 Sequence: TTGTGACCTGCTTCACAT Locus tag: SAV_4837 Name: nuoA Funciton: NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3) Locus tag: SAV_4838 Name: nuoB Funciton: NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3) Locus tag: SAV_4839 Name: nuoC Funciton: NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3) Locus tag: SAV_4840 Name: nuoD Funciton: NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3) Locus tag: SAV_4841 Name: nuoE Funciton: NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3) Locus tag: SAV_4842 Name: nuoF Funciton: NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3) Locus tag: SAV_4843 Name: nuoG Funciton: NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3) Locus tag: SAV_4844 Name: nuoH Funciton: NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3) Locus tag: SAV_4845 Name: nuoI Funciton: NADH-ubiquinone oxidoreductase chain I (EC 1.6.5.3) Locus tag: SAV_4846 Name: nuoJ Funciton: NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3) Locus tag: SAV_4847 Name: nuoK Funciton: NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3) Locus tag: SAV_4848 Name: nuoL Funciton: NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) Locus tag: SAV_4849 Name: nuoM Funciton: NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3) Locus tag: SAV_4850 Name: nuoN Funciton: NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)
	SAV_4837	nuoA	NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3)
	SAV_4838	nuoB	NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3)
	SAV_4839	nuoC	NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)
	SAV_4840	nuoD	NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)
	SAV_4841	nuoE	NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)
	SAV_4842	nuoF	NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3)
	SAV_4843	nuoG	NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)
	SAV_4844	nuoH	NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3)
	SAV_4845	nuoI	NADH-ubiquinone oxidoreductase chain I (EC 1.6.5.3)
	SAV_4846	nuoJ	NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)
	SAV_4847	nuoK	NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)
	SAV_4848	nuoL	NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)
	SAV_4849	nuoM	NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3)
	SAV_4850	nuoN	NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)
Position: -16 Score: 3.9 Sequence: ATGCGAAACTTTTCACAT Locus tag: SAV_4798 Name: resA Funciton: Thiol:disulfide oxidoreductase related to ResA Locus tag: SAV_4799 Name: ccdA Funciton: Cytochrome c-type biogenesis protein CcdA (DsbD analog) Locus tag: SAV_4800 Name: resB Funciton: Ccs1/ResB-related putative cytochrome C-type biogenesis protein Locus tag: SAV_4801 Name: resC Funciton: Cytochrome c-type biogenesis protein CcsA/ResC
	SAV_4798	resA	Thiol:disulfide oxidoreductase related to ResA
	SAV_4799	ccdA	Cytochrome c-type biogenesis protein CcdA (DsbD analog)
	SAV_4800	resB	Ccs1/ResB-related putative cytochrome C-type biogenesis protein
	SAV_4801	resC	Cytochrome c-type biogenesis protein CcsA/ResC
Position: -36 Score: 4.8 Sequence: TTGTGCACCGTCGCACAA Locus tag: SAV_3538 Name: SCO3101 Funciton: Putative lipoprotein Locus tag: SAV_3537 Name: mazG Funciton: Triphosphate pyrophosphohydrolase MazG
	SAV_3538	SCO3101	Putative lipoprotein
	SAV_3537	mazG	Triphosphate pyrophosphohydrolase MazG
Position: -98 Score: 6 Sequence: ATGTGAACGCGTTCACAA Locus tag: SAV_4260 Name: cydA Funciton: Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-) Locus tag: SAV_4259 Name: cydB Funciton: Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-) Locus tag: SAV_4258 Name: cydCD Funciton: ABC transporter permease CydC / ATP-binding protein CydD
	SAV_4260	cydA	Cytochrome d ubiquinol oxidase subunit I (EC 1.10.3.-)
	SAV_4259	cydB	Cytochrome d ubiquinol oxidase subunit II (EC 1.10.3.-)
	SAV_4258	cydCD	ABC transporter permease CydC / ATP-binding protein CydD

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of Rex in Streptomyces avermitilis MA-4680

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --