Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of CmbR in Streptococcus mutans UA159

Properties
Regulator type: Transcription factor
TF locus tag: SMU.852
Regulator family: LysR
Regulation mode: repressor (activator)
Biological process: Cysteine metabolism
Effector: O-acetyl-L-serine
Regulog: CmbR - Streptococcaceae
Statistics of regulated genes:
- Genes 14
- Operons 6
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 104 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -175
Score: 5.3
Sequence: GCTATAAATTTTATTTATGAC
Position: -110
Score: 5
Sequence: GCCATAAGAAAAAGTTATCAC
Locus tag: SMU.930c
Name: homR
Funciton: Homocysteine biosynthesis transcriptional regulato HomR, LysR family
homR
Homocysteine biosynthesis transcriptional regulato HomR, LysR family

Position: -168
Score: 5
Sequence: GTGATAACTTTTTCTTATGGC
Position: -103
Score: 5.3
Sequence: GTCATAAATAAAATTTATAGC
Locus tag: SMU.932
Name: tcyD
Funciton: Predicted uroporphyrinogen-III decarboxylase
Locus tag: SMU.933
Name: tcyE
Funciton: Predicted cysteine ABC transporter, substrate-binding protein
Locus tag: SMU.934
Name: tcyF
Funciton: Predicted cysteine ABC transporter, permease protein 1
Locus tag: SMU.935
Name: tcyG
Funciton: Predicted cysteine ABC transporter, permease protein 2
Locus tag: SMU.936
Name: tcyH
Funciton: Predicted cysteine ABC transporter, ATP-binding protein
tcyD
Predicted uroporphyrinogen-III decarboxylase
tcyE
Predicted cysteine ABC transporter, substrate-binding protein
tcyF
Predicted cysteine ABC transporter, permease protein 1
tcyG
Predicted cysteine ABC transporter, permease protein 2
tcyH
Predicted cysteine ABC transporter, ATP-binding protein

Position: -188
Score: 4.6
Sequence: GTTATAGATGAAAACTATAAC
Locus tag: SMU.873
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Locus tag: SMU.874
Name: metH
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) / Homolog of homocysteine-binding domain
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
metH
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) / Homolog of homocysteine-binding domain

Position: -110
Score: 4.3
Sequence: CTTATAGTTTCTTTTTATAGC
Locus tag: SMU.1675
Name: metB
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: SMU.1674
Name: metC
Funciton: L-cysteine desulfhydrase
metB
Cystathionine gamma-synthase (EC 2.5.1.48)
metC
L-cysteine desulfhydrase

Position: -102
Score: 5.8
Sequence: GTGATAGAAAAATATTATCAC
Position: -80
Score: 5
Sequence: GTGATAGGAAAAAACTATTAT
Locus tag: SMU.459
Name: tcyA
Funciton: Cystine ABC transporter, substrate-binding protein
Locus tag: SMU.460
Name: tcyB
Funciton: Cystine ABC transporter, permease protein
Locus tag: SMU.461
Name: tcyC
Funciton: Cystine ABC transporter, ATP-binding protein
tcyA
Cystine ABC transporter, substrate-binding protein
tcyB
Cystine ABC transporter, permease protein
tcyC
Cystine ABC transporter, ATP-binding protein

Position: -98
Score: 6
Sequence: GTGATAGAATTTTCTTATCAC
Position: -76
Score: 4.6
Sequence: GTGATAGAAATTATATAATAG
Locus tag: SMU.1942c
Name: gshT
Funciton: Predicted glutathione ABC transporter, substrate-binding protein
gshT
Predicted glutathione ABC transporter, substrate-binding protein
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