Regulon of RegR in Streptococcus pyogenes M1 GAS

Properties
Regulator type:	Transcription factor
TF locus tag:	SPy0627
Regulator family:	LacI
Regulation mode:	repressor
Biological process:	Hyaluronate utilization
Effector:	Hyaluronate oligosaccharide phosphate
Regulog:	RegR - Streptococcaceae
Statistics of regulated genes:
- Genes	12
- Operons	3
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 27 sites [see more]

Member of regulog collections

By taxonomy - Streptococcaceae
By TF family - LacI
By effector - Hyaluronate oligosaccharide phosphate
By pathway - Hyaluronate utilization

Regulated operons
	Locus Tag	Name	Function
Position: -54 Score: 5.5 Sequence: TTAGTAAATCAATTTACTTT Locus tag: SPy1032 Name: hyl Funciton: Hyaluronate lyase precursor (EC 4.2.2.1)
	SPy1032	hyl	Hyaluronate lyase precursor (EC 4.2.2.1)
Position: -281 Score: 5.1 Sequence: AAAGTAAACTAGTTTTGTCA Position: -33 Score: 4.6 Sequence: TGAGTAAACCGGTAAACCGA Locus tag: SPy0634 Name: hylD Funciton: PTS system, hyaluronate-oligosaccharide-specific IIA component (EC 2.7.1.69) Locus tag: SPy0632 Name: ugl Funciton: Unsaturated glucuronyl hydrolase (EC 3.2.1.-) Locus tag: SPy0631 Name: hylE Funciton: PTS system, hyaluronate-oligosaccharide-specific IIB component (EC 2.7.1.69) Locus tag: SPy0630 Name: hylF Funciton: PTS system, hyaluronate-oligosaccharide-specific IIC component (EC 2.7.1.69) Locus tag: SPy0629 Name: hylG Funciton: PTS system, hyaluronate-oligosaccharide-specific IID component (EC 2.7.1.69) Locus tag: SPy0628 Name: ohl Funciton: Oligohyaluronate lyase (EC 4.2.2.-) Locus tag: SPy0627 Name: regR Funciton: Transcriptional regulator of hyaluronate and KDG utilization, LacI family
	SPy0634	hylD	PTS system, hyaluronate-oligosaccharide-specific IIA component (EC 2.7.1.69)
	SPy0632	ugl	Unsaturated glucuronyl hydrolase (EC 3.2.1.-)
	SPy0631	hylE	PTS system, hyaluronate-oligosaccharide-specific IIB component (EC 2.7.1.69)
	SPy0630	hylF	PTS system, hyaluronate-oligosaccharide-specific IIC component (EC 2.7.1.69)
	SPy0629	hylG	PTS system, hyaluronate-oligosaccharide-specific IID component (EC 2.7.1.69)
	SPy0628	ohl	Oligohyaluronate lyase (EC 4.2.2.-)
	SPy0627	regR	Transcriptional regulator of hyaluronate and KDG utilization, LacI family
Position: -74 Score: 5.1 Sequence: TGACAAAACTAGTTTACTTT Position: -45 Score: 6.1 Sequence: TTGGTAAACAGGTTTACTTA Locus tag: SPy0636 Name: kduD Funciton: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127) Locus tag: SPy0637 Name: kduI Funciton: 5-keto-4-deoxyuronate isomerase (EC 5.3.1.17) Locus tag: SPy0638 Name: kdgK Funciton: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45) Locus tag: SPy0639 Name: kdgA Funciton: 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)
	SPy0636	kduD	2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase (EC 1.1.1.127)
	SPy0637	kduI	5-keto-4-deoxyuronate isomerase (EC 5.3.1.17)
	SPy0638	kdgK	2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)
	SPy0639	kdgA	2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD